Hmdb loader

HMDBP01689 (NAD(P)H dehydrogenase [quinone] 1) Metabolite Associations

Displaying all 15 metabolite protein links
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB0000217NADP53-59-8ThumbC21H28N7O17P3743.405
743.075452041		Not Available
HMDB0000221NADPH53-57-6ThumbC21H30N7O17P3745.4209
745.091102105		Not Available
HMDB0000902NAD53-84-9ThumbC21H27N7O14P2663.4251
663.109121631		Not Available
HMDB0001248FAD146-14-5ThumbC27H33N9O15P2785.5497
785.157134455		Not Available
HMDB0001487NADH58-68-4ThumbC21H29N7O14P2665.441
665.124771695		Not Available
HMDB0001892Menadione58-27-5ThumbC11H8O2172.18
172.0524295
  1. Munday R, Smith BL, Munday CM: Effect of butylated hydroxyanisole on the toxicity of 2-hydroxy-1,4-naphthoquinone to rats. Chem Biol Interact. 1999 Feb 12;117(3):241-56. [PubMed:10190578 ]
  2. Chiou TJ, Wang YT, Tzeng WF: DT-diaphorase protects against menadione-induced oxidative stress. Toxicology. 1999 Nov 29;139(1-2):103-10. [PubMed:10614691 ]
  3. Munday R, Smith BL, Munday CM: Effect of inducers of DT-diaphorase on the toxicity of 2-methyl- and 2-hydroxy-1,4-naphthoquinone to rats. Chem Biol Interact. 1999 Dec 15;123(3):219-37. [PubMed:10654840 ]
  4. Ip SP, Yiu HY, Ko KM: Schisandrin B protects against menadione-induced hepatotoxicity by enhancing DT-diaphorase activity. Mol Cell Biochem. 2000 May;208(1-2):151-5. [PubMed:10939639 ]
  5. Kishi T, Takahashi T, Mizobuchi S, Mori K, Okamoto T: Effect of dicumarol, a Nad(P)h: quinone acceptor oxidoreductase 1 (DT-diaphorase) inhibitor on ubiquinone redox cycling in cultured rat hepatocytes. Free Radic Res. 2002 Apr;36(4):413-9. [PubMed:12069105 ]
HMDB0001893alpha-Tocopherol59-02-9ThumbC29H50O2430.7061
430.381080844
  1. Feng Z, Liu Z, Li X, Jia H, Sun L, Tian C, Jia L, Liu J: alpha-Tocopherol is an effective Phase II enzyme inducer: protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells. J Nutr Biochem. 2010 Dec;21(12):1222-31. doi: 10.1016/j.jnutbio.2009.10.010. Epub 2010 Feb 12. [PubMed:20153624 ]
HMDB0002434Hydroquinone123-31-9ThumbC6H6O2110.1106
110.036779436		Not Available
HMDB0003364Quinone106-51-4ThumbC6H4O2108.0948
108.021129372		Not Available
HMDB0003555Vitamin K184-80-0ThumbC31H46O2450.6957
450.349780716		Not Available
HMDB0004198Phylloquinol572-96-3ThumbC31H48O2452.7116
452.36543078		Not Available
HMDB0014411Dicumarol66-76-2ThumbC19H12O6336.295
336.063388116
  1. Chen S, Wu K, Zhang D, Sherman M, Knox R, Yang CS: Molecular characterization of binding of substrates and inhibitors to DT-diaphorase: combined approach involving site-directed mutagenesis, inhibitor-binding analysis, and computer modeling. Mol Pharmacol. 1999 Aug;56(2):272-8. [PubMed:10419545 ]
  2. Jaiswal AK: Characterization and partial purification of microsomal NAD(P)H:quinone oxidoreductases. Arch Biochem Biophys. 2000 Mar 1;375(1):62-8. [PubMed:10683249 ]
  3. Joseph P, Jaiswal AK: A unique cytosolic activity related but distinct from NQO1 catalyses metabolic activation of mitomycin C. Br J Cancer. 2000 Apr;82(7):1305-11. [PubMed:10755406 ]
  4. Floreani M, Napoli E, Palatini P: Protective action of cardiac DT-diaphorase against menadione toxicity in guinea pig isolated atria. Biochem Pharmacol. 2000 Aug 15;60(4):601-5. [PubMed:10874136 ]
  5. Arriagada C, Dagnino-Subiabre A, Caviedes P, Armero JM, Caviedes R, Segura-Aguilar J: Studies of aminochrome toxicity in a mouse derived neuronal cell line: is this toxicity mediated via glutamate transmission? Amino Acids. 2000;18(4):363-73. [PubMed:10949919 ]
  6. Preusch PC, Smalley DM: Vitamin K1 2,3-epoxide and quinone reduction: mechanism and inhibition. Free Radic Res Commun. 1990;8(4-6):401-15. [PubMed:2113031 ]
HMDB0030017Menatetrenone863-61-6ThumbC31H40O2444.659
444.302830528		Not Available
HMDB0059597Hydrogen IonThumbH1.0079
1.007825032		Not Available
HMDB0060487MenaquinolThumbC21H26O2310.4299
310.193280076		Not Available
Displaying all 15 metabolite protein links