Hmdb loader

HMDBP00824 (Glutathione S-transferase A2) Metabolite Associations

Displaying metabolite protein links 1 - 25 of 47 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB0000125Glutathione70-18-8ThumbC10H17N3O6S307.323
307.083805981
  1. Guruvayoorappan C, Afira AH, Kuttan G: Antioxidant potential of Biophytum sensitivum extract in vitro and in vivo. J Basic Clin Physiol Pharmacol. 2006;17(4):255-67. [PubMed:17338281 ]
  2. Hayes JD, Flanagan JU, Jowsey IR: Glutathione transferases. Annu Rev Pharmacol Toxicol. 2005;45:51-88. [PubMed:15822171 ]
  3. Armstrong RN: Glutathione S-transferases: reaction mechanism, structure, and function. Chem Res Toxicol. 1991 Mar-Apr;4(2):131-40. [PubMed:1782341 ]
  4. Sharma P, Ahmad Shah Z, Kumar A, Islam F, Mishra KP: Role of combined administration of Tiron and glutathione against aluminum-induced oxidative stress in rat brain. J Trace Elem Med Biol. 2007;21(1):63-70. Epub 2007 Feb 6. [PubMed:17317527 ]
  5. Skamarauskas J, Carter W, Fowler M, Madjd A, Lister T, Mavroudis G, Ray DE: The selective neurotoxicity produced by 3-chloropropanediol in the rat is not a result of energy deprivation. Toxicology. 2007 Apr 11;232(3):268-76. Epub 2007 Jan 21. [PubMed:17321661 ]
  6. Ozkilic AC, Cengiz M, Ozaydin A, Cobanoglu A, Kanigur G: The role of N-acetylcysteine treatment on anti-oxidative status in patients with type II diabetes mellitus. J Basic Clin Physiol Pharmacol. 2006;17(4):245-54. [PubMed:17338280 ]
  7. Gupta S, Sarotra P, Aggarwal R, Dutta N, Agnihotri N: Role of oxidative stress in celecoxib-induced renal damage in wistar rats. Dig Dis Sci. 2007 Nov;52(11):3092-8. Epub 2007 Mar 31. [PubMed:17401685 ]
HMDB0001448Sulfate14808-79-8ThumbH2O4S98.078
97.967379242		Not Available
HMDB0001893alpha-Tocopherol59-02-9ThumbC29H50O2430.7061
430.381080844
  1. Feng Z, Liu Z, Li X, Jia H, Sun L, Tian C, Jia L, Liu J: alpha-Tocopherol is an effective Phase II enzyme inducer: protective effects on acrolein-induced oxidative stress and mitochondrial dysfunction in human retinal pigment epithelial cells. J Nutr Biochem. 2010 Dec;21(12):1222-31. doi: 10.1016/j.jnutbio.2009.10.010. Epub 2010 Feb 12. [PubMed:20153624 ]
HMDB0002111Water7732-18-5ThumbH2O18.0153
18.010564686		Not Available
HMDB0002306Hydrochloric acid7647-01-0ThumbClH36.461
35.976677739		Not Available
HMDB0002500Bromide7726-95-6ThumbBr79.904
78.918337647		Not Available
HMDB0006215Naphthalene epoxide17180-88-0ThumbC10H8O144.1699
144.057514878		Not Available
HMDB00065582,3-Epoxyaflatoxin B142583-46-0ThumbC17H12O7328.273
328.058302738		Not Available
HMDB0014746Chloroquine54-05-7ThumbC18H26ClN3319.872
319.181525554
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
HMDB0014774Clofibrate637-07-0ThumbC12H15ClO3242.699
242.070972053
  1. Foliot A, Touchard D, Mallet L: Inhibition of liver glutathione S-transferase activity in rats by hypolipidemic drugs related or unrelated to clofibrate. Biochem Pharmacol. 1986 May 15;35(10):1685-90. [PubMed:3707598 ]
  2. Foliot A, Touchard D, Celier C: Impairment of hepatic glutathione S-transferase activity as a cause of reduced biliary sulfobromophthalein excretion in clofibrate-treated rats. Biochem Pharmacol. 1984 Sep 15;33(18):2829-34. [PubMed:6477642 ]
HMDB0015039Ethacrynic acid58-54-8ThumbC13H12Cl2O4303.138
302.011264286
  1. Depeille P, Cuq P, Passagne I, Evrard A, Vian L: Combined effects of GSTP1 and MRP1 in melanoma drug resistance. Br J Cancer. 2005 Jul 25;93(2):216-23. [PubMed:15999103 ]
  2. Awasthi S, Srivastava SK, Ahmad F, Ahmad H, Ansari GA: Interactions of glutathione S-transferase-pi with ethacrynic acid and its glutathione conjugate. Biochim Biophys Acta. 1993 Jul 10;1164(2):173-8. [PubMed:8329448 ]
  3. Iersel ML, Ploemen JP, Struik I, van Amersfoort C, Keyzer AE, Schefferlie JG, van Bladeren PJ: Inhibition of glutathione S-transferase activity in human melanoma cells by alpha,beta-unsaturated carbonyl derivatives. Effects of acrolein, cinnamaldehyde, citral, crotonaldehyde, curcumin, ethacrynic acid, and trans-2-hexenal. Chem Biol Interact. 1996 Oct 21;102(2):117-32. [PubMed:8950226 ]
  4. van Iersel ML, Ploemen JP, Lo Bello M, Federici G, van Bladeren PJ: Interactions of alpha, beta-unsaturated aldehydes and ketones with human glutathione S-transferase P1-1. Chem Biol Interact. 1997 Dec 12;108(1-2):67-78. [PubMed:9463521 ]
  5. Morrow CS, Smitherman PK, Townsend AJ: Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin. Biochem Pharmacol. 1998 Oct 15;56(8):1013-21. [PubMed:9776312 ]
HMDB0015143Busulfan55-98-1ThumbC6H14O6S2246.302
246.02317956
  1. Vassord C, Lapoumeroulie C, Koumaravelou K, Srivastava A, Krishnamoorthy R: Endothelial cells do not express GSTA1: potential relevance to busulfan-mediated endothelial damage during haematopoietic stem cell transplantation. Eur J Haematol. 2008 Apr;80(4):299-302. doi: 10.1111/j.1600-0609.2008.01031.x. Epub 2008 Jan 14. [PubMed:18194479 ]
HMDB0029593Trichloroethylene79-01-6ThumbC2HCl3131.388
129.914383153		Not Available
HMDB0059597Hydrogen IonThumbH1.0079
1.007825032		Not Available
HMDB0060091Benzo[a]pyrene-4,5-oxideThumbC20H12O268.3087
268.088815006		Not Available
HMDB0060299(1R)-Glutathionyl-(2R)-hydroxy-1,2-dihydronaphthaleneThumbC20H25N3O7S451.493
451.141320859		Not Available
HMDB0060300(1R)-Hydroxy-(2R)-glutathionyl-1,2-dihydronaphthaleneThumbC20H25N3O7S451.493
451.141320859		Not Available
HMDB0060301(1S,2R)-Naphthalene 1,2-oxideThumbC10H8O144.1699
144.057514878		Not Available
HMDB0060302(1S)-Hydroxy-(2S)-glutathionyl-1,2-dihydronaphthaleneThumbC20H25N3O7S451.493
451.141320859		Not Available
HMDB00603261-Nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthaleneThumbC20H24N4O9S496.491
496.126399076		Not Available
HMDB00603271-Nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthaleneThumbC20H24N4O9S496.491
496.126399076		Not Available
HMDB00603291-Nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthaleneThumbC20H24N4O9S496.491
496.126399076		Not Available
HMDB00603301-Nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthaleneThumbC20H24N4O9S496.491
496.126399076		Not Available
HMDB00603311-Nitronaphthalene-5,6-oxideThumbC10H7NO3189.1675
189.042593095		Not Available
HMDB00603321-Nitronaphthalene-7,8-oxideThumbC10H7NO3189.1675
189.042593095		Not Available
Displaying metabolite protein links 1 - 25 of 47 in total