Hmdb loader

HMDBP02040 (Canalicular multispecific organic anion transporter 2) Metabolite Associations

Displaying metabolite protein links 76 - 100 of 100 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB000243112b-Hydroxy-5b-cholanoic acid15173-23-6ThumbC24H40O3376.5726
376.297745146		Not Available
HMDB00024517b,12a-Dihydroxycholanoic acid84413-81-0ThumbC24H40O4392.572
392.292659768		Not Available
HMDB00024887a,12b-dihydroxy-5b-Cholan-24-oic acid84413-82-1ThumbC24H40O4392.572
392.292659768		Not Available
HMDB00024927a-Hydroxy-5b-cholanic acid28083-34-3ThumbC24H40O3376.5726
376.297745146		Not Available
HMDB0002497Glycochenodeoxycholate-3-sulfate67030-54-0ThumbC26H43NO8S529.687
529.270938047		Not Available
HMDB00025043-Sulfodeoxycholic acid67030-48-2ThumbC23H38O7S458.609
458.23382426		Not Available
HMDB0002522Chenodeoxycholic acid sulfate59132-31-9ThumbC24H40O7S472.635
472.249474324		Not Available
HMDB0002536Isodeoxycholic acid566-17-6ThumbC24H40O4392.572
392.292659768		Not Available
HMDB00025853beta,12beta-Dihydroxy-5beta-cholanoic acid84848-09-9ThumbC24H40O4392.572
392.292659768		Not Available
HMDB0002586Chenodeoxycholic acid 3-sulfate59132-32-0ThumbC24H40O7S472.635
472.249474324		Not Available
HMDB0002642Ursodeoxycholic acid 3-sulfate68780-73-4ThumbC24H40O7S472.635
472.249474324		Not Available
HMDB0006898Chenodeoxyglycocholic acidThumbC26H43NO5449.6233
449.314123491		Not Available
HMDB0013961O-Desmethylverapamil (D-702)ThumbC26H36N2O4440.575
440.26750765
  1. Zeng H, Chen ZS, Belinsky MG, Rea PA, Kruh GD: Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer Res. 2001 Oct 1;61(19):7225-32. [PubMed:11585759 ]
HMDB00140105-HydroxyomeprazoleThumbC17H19N3O4S361.415
361.109626801
  1. Hitzl M, Klein K, Zanger UM, Fritz P, Nussler AK, Neuhaus P, Fromm MF: Influence of omeprazole on multidrug resistance protein 3 expression in human liver. J Pharmacol Exp Ther. 2003 Feb;304(2):524-30. [PubMed:12538803 ]
HMDB0014656Cisplatin15663-27-1ThumbCl2H4N2Pt298.035
296.939928001
  1. Schrenk D, Baus PR, Ermel N, Klein C, Vorderstemann B, Kauffmann HM: Up-regulation of transporters of the MRP family by drugs and toxins. Toxicol Lett. 2001 Mar 31;120(1-3):51-7. [PubMed:11323161 ]
HMDB0014681Vincristine57-22-7ThumbC46H56N4O10824.9576
824.399644032
  1. Zeng H, Chen ZS, Belinsky MG, Rea PA, Kruh GD: Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer Res. 2001 Oct 1;61(19):7225-32. [PubMed:11585759 ]
HMDB0014703Methotrexate59-05-2ThumbC20H22N8O5454.4393
454.171315854
  1. Zeng H, Chen ZS, Belinsky MG, Rea PA, Kruh GD: Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer Res. 2001 Oct 1;61(19):7225-32. [PubMed:11585759 ]
  2. Akita H, Suzuki H, Hirohashi T, Takikawa H, Sugiyama Y: Transport activity of human MRP3 expressed in Sf9 cells: comparative studies with rat MRP3. Pharm Res. 2002 Jan;19(1):34-41. [PubMed:11837698 ]
  3. Oleschuk CJ, Deeley RG, Cole SP: Substitution of Trp1242 of TM17 alters substrate specificity of human multidrug resistance protein 3. Am J Physiol Gastrointest Liver Physiol. 2003 Feb;284(2):G280-9. Epub 2002 Oct 9. [PubMed:12388190 ]
  4. Hirohashi T, Suzuki H, Sugiyama Y: Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3). J Biol Chem. 1999 May 21;274(21):15181-5. [PubMed:10329726 ]
  5. Zeng H, Liu G, Rea PA, Kruh GD: Transport of amphipathic anions by human multidrug resistance protein 3. Cancer Res. 2000 Sep 1;60(17):4779-84. [PubMed:10987286 ]
  6. Paumi CM, Wright M, Townsend AJ, Morrow CS: Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells. Biochemistry. 2003 May 13;42(18):5429-37. [PubMed:12731885 ]
  7. Li T, Ito K, Horie T: Transport of fluorescein methotrexate by multidrug resistance-associated protein 3 in IEC-6 cells. Am J Physiol Gastrointest Liver Physiol. 2003 Sep;285(3):G602-10. [PubMed:12909565 ]
  8. Zehnpfennig B, Urbatsch IL, Galla HJ: Functional reconstitution of human ABCC3 into proteoliposomes reveals a transport mechanism with positive cooperativity. Biochemistry. 2009 May 26;48(20):4423-30. doi: 10.1021/bi9001908. [PubMed:19334674 ]
HMDB0014911Etoposide33419-42-0ThumbC29H32O13588.5566
588.18429111
  1. Zelcer N, Saeki T, Reid G, Beijnen JH, Borst P: Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3). J Biol Chem. 2001 Dec 7;276(49):46400-7. [PubMed:11581266 ]
  2. Zeng H, Chen ZS, Belinsky MG, Rea PA, Kruh GD: Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer Res. 2001 Oct 1;61(19):7225-32. [PubMed:11585759 ]
  3. Zehnpfennig B, Urbatsch IL, Galla HJ: Functional reconstitution of human ABCC3 into proteoliposomes reveals a transport mechanism with positive cooperativity. Biochemistry. 2009 May 26;48(20):4423-30. doi: 10.1021/bi9001908. [PubMed:19334674 ]
HMDB0015132Doxorubicin23214-92-8ThumbC27H29NO11543.5193
543.174060775
  1. Zeng H, Chen ZS, Belinsky MG, Rea PA, Kruh GD: Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer Res. 2001 Oct 1;61(19):7225-32. [PubMed:11585759 ]
HMDB0015146Metyrapone54-36-4ThumbC14H14N2O226.2738
226.11061308
  1. Teng S, Jekerle V, Piquette-Miller M: Induction of ABCC3 (MRP3) by pregnane X receptor activators. Drug Metab Dispos. 2003 Nov;31(11):1296-9. [PubMed:14570758 ]
HMDB0015151Glyburide10238-21-8ThumbC23H28ClN3O5S494.004
493.143819418
  1. Gedeon C, Behravan J, Koren G, Piquette-Miller M: Transport of glyburide by placental ABC transporters: implications in fetal drug exposure. Placenta. 2006 Nov-Dec;27(11-12):1096-102. Epub 2006 Feb 3. [PubMed:16460798 ]
HMDB0015166Probenecid57-66-9ThumbC13H19NO4S285.359
285.103478791
  1. Zelcer N, Saeki T, Reid G, Beijnen JH, Borst P: Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3). J Biol Chem. 2001 Dec 7;276(49):46400-7. [PubMed:11581266 ]
  2. Zeng H, Chen ZS, Belinsky MG, Rea PA, Kruh GD: Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport. Cancer Res. 2001 Oct 1;61(19):7225-32. [PubMed:11585759 ]
  3. Zamek-Gliszczynski MJ, Xiong H, Patel NJ, Turncliff RZ, Pollack GM, Brouwer KL: Pharmacokinetics of 5 (and 6)-carboxy-2',7'-dichlorofluorescein and its diacetate promoiety in the liver. J Pharmacol Exp Ther. 2003 Feb;304(2):801-9. [PubMed:12538836 ]
HMDB0015179Rifampin13292-46-1ThumbC43H58N4O12822.9402
822.40512334
  1. Teng S, Jekerle V, Piquette-Miller M: Induction of ABCC3 (MRP3) by pregnane X receptor activators. Drug Metab Dispos. 2003 Nov;31(11):1296-9. [PubMed:14570758 ]
HMDB0015247Nifedipine21829-25-4ThumbC17H18N2O6346.3346
346.116486318
  1. Teng S, Jekerle V, Piquette-Miller M: Induction of ABCC3 (MRP3) by pregnane X receptor activators. Drug Metab Dispos. 2003 Nov;31(11):1296-9. [PubMed:14570758 ]
HMDB0015269Sulfinpyrazone57-96-5ThumbC23H20N2O3S404.482
404.119463206
  1. Zelcer N, Saeki T, Reid G, Beijnen JH, Borst P: Characterization of drug transport by the human multidrug resistance protein 3 (ABCC3). J Biol Chem. 2001 Dec 7;276(49):46400-7. [PubMed:11581266 ]
Displaying metabolite protein links 76 - 100 of 100 in total