Hmdb loader

HMDBP01554 (Cytochrome P450 3A5) Metabolite Associations

Displaying metabolite protein links 26 - 50 of 162 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB000395519-Hydroxyandrost-4-ene-3,17-dione510-64-5ThumbC19H26O3302.4079
302.188194698		Not Available
HMDB00039567a-Hydroxytestosterone2141-17-5ThumbC19H28O3304.4238
304.203844762		Not Available
HMDB000395919-Oxotestosterone4075-13-2ThumbC19H26O3302.4079
302.188194698		Not Available
HMDB00040816-Hydroxymelatonin2208-41-5ThumbC13H16N2O3248.2777
248.116092388		Not Available
HMDB000424415(S)-HPETE70981-96-3ThumbC20H32O4336.4657
336.230059512		Not Available
HMDB000426414,15-Epoxy-5,8,11-eicosatrienoic acid81276-03-1ThumbC20H32O3320.4663
320.23514489		Not Available
HMDB000467311,12-Epoxyeicosatrienoic acid123931-40-8ThumbC20H32O3320.473
320.23514489		Not Available
HMDB000468016(R)-HETEThumbC20H32O3320.4663
320.23514489		Not Available
HMDB000468411,12,15-THETAThumbC20H34O5354.481
354.240624198		Not Available
HMDB000469311H-14,15-EETA219535-29-2ThumbC20H32O4336.4657
336.230059512		Not Available
HMDB000469411,14,15-THETAThumbC20H34O5354.481
354.240624198		Not Available
HMDB00047019,10-Epoxyoctadecenoic acidThumbC18H32O3296.4449
296.23514489		Not Available
HMDB000470212,13-EpOMEThumbC18H32O3296.4449
296.23514489		Not Available
HMDB0004995Codeine76-57-3ThumbC18H21NO3299.3642
299.152143543		Not Available
HMDB0005011Clopidogrel113665-84-2ThumbC16H16ClNO2S321.822
321.059027158		Not Available
HMDB0005036Fluticasone propionate80474-14-2ThumbC25H31F3O5S500.571
500.184429407
  1. Pearce RE, Leeder JS, Kearns GL: Biotransformation of fluticasone: in vitro characterization. Drug Metab Dispos. 2006 Jun;34(6):1035-40. Epub 2006 Mar 24. [PubMed:16565171 ]
  2. Murai T, Reilly CA, Ward RM, Yost GS: The inhaled glucocorticoid fluticasone propionate efficiently inactivates cytochrome P450 3A5, a predominant lung P450 enzyme. Chem Res Toxicol. 2010 Aug 16;23(8):1356-64. doi: 10.1021/tx100124k. [PubMed:20707410 ]
HMDB0005038Citalopram59729-33-8ThumbC20H21FN2O324.3919
324.163791509		Not Available
HMDB0005042Aripiprazole129722-12-9ThumbC23H27Cl2N3O2448.385
447.148032537		Not Available
HMDB000505015H-11,12-EETA877878-78-9ThumbC20H32O4336.4657
336.230059512		Not Available
HMDB000676819-Oxoandrost-4-ene-3,17-dioneThumbC19H24O3300.3921
300.172544634		Not Available
HMDB000676919-Hydroxytestosterone2126-37-6ThumbC19H28O3304.4238
304.203844762		Not Available
HMDB001113619(S)-HETE79551-85-2ThumbC20H32O3320.4663
320.23514489		Not Available
HMDB0012242Ketoconazole65277-42-1ThumbC26H28Cl2N4O4531.431
530.148760818		Not Available
HMDB0013846E-3179ThumbC22H21ClN6O420.895
420.146537031
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
HMDB00138583-Dechloroethylifosfamide36761-83-8ThumbC5H12ClN2O2P198.588
198.032491857
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [PubMed:19515014 ]
  2. Lokiec F: Ifosfamide: pharmacokinetic properties for central nervous system metastasis prevention. Ann Oncol. 2006 May;17 Suppl 4:iv33-6. [PubMed:16702183 ]
  3. Roy P, Yu LJ, Crespi CL, Waxman DJ: Development of a substrate-activity based approach to identify the major human liver P-450 catalysts of cyclophosphamide and ifosfamide activation based on cDNA-expressed activities and liver microsomal P-450 profiles. Drug Metab Dispos. 1999 Jun;27(6):655-66. [PubMed:10348794 ]
Displaying metabolite protein links 26 - 50 of 162 in total