Hmdb loader

HMDBP00724 (Cholesterol side-chain cleavage enzyme, mitochondrial) Metabolite Associations

Displaying metabolite protein links 1 - 25 of 28 in total
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB00000327-Dehydrocholesterol434-16-2ThumbC27H44O384.6377
384.33921603
  1. Guryev O, Carvalho RA, Usanov S, Gilep A, Estabrook RW: A pathway for the metabolism of vitamin D3: unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1). Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14754-9. Epub 2003 Dec 1. [PubMed:14657394 ]
HMDB0000067Cholesterol57-88-5ThumbC27H46O386.6535
386.354866094		Not Available
HMDB0000234Testosterone58-22-0ThumbC19H28O2288.4244
288.20893014
  1. Kostic TS, Stojkov NJ, Bjelic MM, Mihajlovic AI, Janjic MM, Andric SA: Pharmacological doses of testosterone upregulated androgen receptor and 3-Beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase and impaired leydig cells steroidogenesis in adult rats. Toxicol Sci. 2011 Jun;121(2):397-407. doi: 10.1093/toxsci/kfr063. Epub 2011 Apr 6. [PubMed:21427060 ]
HMDB0000253Pregnenolone145-13-1ThumbC21H32O2316.4776
316.240230268		Not Available
HMDB000036317a-Hydroxypregnenolone387-79-1ThumbC21H32O3332.477
332.23514489		Not Available
HMDB0000876Vitamin D367-97-0ThumbC27H44O384.6377
384.33921603
  1. Guryev O, Carvalho RA, Usanov S, Gilep A, Estabrook RW: A pathway for the metabolism of vitamin D3: unique hydroxylated metabolites formed during catalysis with cytochrome P450scc (CYP11A1). Proc Natl Acad Sci U S A. 2003 Dec 9;100(25):14754-9. Epub 2003 Dec 1. [PubMed:14657394 ]
  2. Tuckey RC, Janjetovic Z, Li W, Nguyen MN, Zmijewski MA, Zjawiony J, Slominski A: Metabolism of 1alpha-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1alpha,20-dihydroxyvitamin D3. J Steroid Biochem Mol Biol. 2008 Dec;112(4-5):213-9. doi: 10.1016/j.jsbmb.2008.10.005. Epub 2008 Oct 21. [PubMed:19000766 ]
  3. Tuckey RC, Nguyen MN, Slominski A: Kinetics of vitamin D3 metabolism by cytochrome P450scc (CYP11A1) in phospholipid vesicles and cyclodextrin. Int J Biochem Cell Biol. 2008;40(11):2619-26. doi: 10.1016/j.biocel.2008.05.006. Epub 2008 May 20. [PubMed:18573681 ]
HMDB00013184-Methylpentanal1119-16-0ThumbC6H12O100.1589
100.088815006		Not Available
HMDB0001377Oxygen7782-44-7ThumbO231.9988
31.989829244		Not Available
HMDB0001830Progesterone57-83-0ThumbC21H30O2314.4617
314.224580204		Not Available
HMDB0001917Digoxin20830-75-5ThumbC41H64O14780.9385
780.429606756		Not Available
HMDB0001922Clotrimazole23593-75-1ThumbC22H17ClN2344.837
344.108026261		Not Available
HMDB0001939Medroxyprogesterone520-85-4ThumbC22H32O3344.4877
344.23514489		Not Available
HMDB0002111Water7732-18-5ThumbH2O18.0153
18.010564686		Not Available
HMDB0003178Heme14875-96-8ThumbC34H32FeN4O4616.487
616.177297665		Not Available
HMDB000403522b-Hydroxycholesterol22348-64-7ThumbC27H46O2402.6529
402.349780716		Not Available
HMDB0005994Hexanal66-25-1ThumbC6H12O100.1589
100.088815006		Not Available
HMDB000628320alpha-Hydroxycholesterol516-72-3ThumbC27H46O2402.6529
402.349780716		Not Available
HMDB000676320a,22b-Dihydroxycholesterol15234-55-6ThumbC27H46O3418.6523
418.344695338		Not Available
HMDB000676417a,20a-DihydroxycholesterolThumbC27H46O3418.6523
418.344695338		Not Available
HMDB00140105-HydroxyomeprazoleThumbC17H19N3O4S361.415
361.109626801
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
HMDB0014501Aminoglutethimide125-84-8ThumbC13H16N2O2232.2783
232.121177766
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. Slominski A, Semak I, Wortsman J, Zjawiony J, Li W, Zbytek B, Tuckey RC: An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2. FEBS J. 2006 Jul;273(13):2891-901. [PubMed:16817851 ]
  3. Oka H, Emori Y, Hayashi Y, Nomoto K: Breakdown of Th cell immune responses and steroidogenic CYP11A1 expression in CD4+ T cells in a murine model implanted with B16 melanoma. Cell Immunol. 2000 Nov 25;206(1):7-15. [PubMed:11161433 ]
HMDB0014995Terbinafine91161-71-6ThumbC21H25N291.4299
291.198699805
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
HMDB0015020Clomifene911-45-5ThumbC26H28ClNO405.96
405.18594223
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
HMDB0015362Saquinavir127779-20-8ThumbC38H50N6O5670.8408
670.38426874
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
HMDB0015364Dexamethasone50-02-2ThumbC22H29FO5392.4611
392.199902243
  1. Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
Displaying metabolite protein links 1 - 25 of 28 in total