Hmdb loader

HMDBP00160 (Methionine synthase) Metabolite Associations

Displaying all 19 metabolite protein links
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB0000607Cyanocobalamin68-19-9ThumbC63H89CoN14O14P1356.3731
1355.575230332
  1. Stover PJ: Vitamin B12 and older adults. Curr Opin Clin Nutr Metab Care. 2010 Jan;13(1):24-7. doi: 10.1097/MCO.0b013e328333d157. [PubMed:19904199 ]
  2. Allen LH: Causes of vitamin B12 and folate deficiency. Food Nutr Bull. 2008 Jun;29(2 Suppl):S20-34; discussion S35-7. [PubMed:18709879 ]
HMDB0000608Cobalt7440-48-4ThumbCo58.9332
58.933200194		Not Available
HMDB0000696Methionine63-68-3ThumbC5H11NO2S149.211
149.051049291
  1. Taurog RE, Matthews RG: Activation of methyltetrahydrofolate by cobalamin-independent methionine synthase. Biochemistry. 2006 Apr 25;45(16):5092-102. [PubMed:16618098 ]
  2. Hughes JA: In vivo hydrolysis of S-adenosyl-L-methionine in Escherichia coli increases export of 5-methylthioribose. Can J Microbiol. 2006 Jun;52(6):599-602. [PubMed:16788729 ]
  3. Reynolds E: Vitamin B12, folic acid, and the nervous system. Lancet Neurol. 2006 Nov;5(11):949-60. [PubMed:17052662 ]
  4. Banks EC, Doughty SW, Toms SM, Wheelhouse RT, Nicolaou A: Inhibition of cobalamin-dependent methionine synthase by substituted benzo-fused heterocycles. FEBS J. 2007 Jan;274(1):287-99. [PubMed:17222188 ]
  5. Yamada K, Kawata T, Wada M, Mori K, Tamai H, Tanaka N, Tadokoro T, Tobimatsu T, Toraya T, Maekawa A: Testicular injury to rats fed on soybean protein-based vitamin B12-deficient diet can be reduced by methionine supplementation. J Nutr Sci Vitaminol (Tokyo). 2007 Apr;53(2):95-101. [PubMed:17615995 ]
HMDB0000742Homocysteine6027-13-0ThumbC4H9NO2S135.185
135.035399227		Not Available
HMDB0000802Pterin2236-60-4ThumbC6H5N5O163.1368
163.049409807		Not Available
HMDB0001185S-Adenosylmethionine485-80-3ThumbC15H23N6O5S399.445
399.145063566		Not Available
HMDB0001248FAD146-14-5ThumbC27H33N9O15P2785.5497
785.157134455		Not Available
HMDB00013965-Methyltetrahydrofolic acid134-35-0ThumbC20H25N7O6459.4558
459.186631567		Not Available
HMDB0001846Tetrahydrofolic acid135-16-0ThumbC19H23N7O6445.4292
445.170981503		Not Available
HMDB0002174Cobalamin13408-78-1ThumbC62H88CoN13O14P1329.369
1328.563777		Not Available
HMDB0002274Methylcobalamin13422-55-4ThumbC63H91CoN13O14P1344.3823
1343.587806391		Not Available
HMDB0002308Hydroxocobalamin13422-51-0ThumbC62H89CoN13O15P1346.3551
1345.567070949
  1. Tkachuck RD, Weinstein PP, Mueller JF: Metabolic fate of cyanocobalamin taken up by Spirometra mansonoides spargana. J Parasitol. 1977 Aug;63(4):694-700. [PubMed:18565 ]
  2. Quadros EV, Jacobsen DW: The dynamics of cobalamin utilization in L-1210 mouse leukemia cells: a model of cellular cobalamin metabolism. Biochim Biophys Acta. 1995 Jun 9;1244(2-3):395-403. [PubMed:7599160 ]
  3. Kolhouse JF, Utley C, Stabler SP, Allen RH: Mechanism of conversion of human apo- to holomethionine synthase by various forms of cobalamin. J Biol Chem. 1991 Dec 5;266(34):23010-5. [PubMed:1744096 ]
  4. Ogier de Baulny H, Gerard M, Saudubray JM, Zittoun J: Remethylation defects: guidelines for clinical diagnosis and treatment. Eur J Pediatr. 1998 Apr;157 Suppl 2:S77-83. [PubMed:9587031 ]
  5. Rosenblatt DS, Thomas IT, Watkins D, Cooper BA, Erbe RW: Vitamin B12 responsive homocystinuria and megaloblastic anemia: heterogeneity in methylcobalamin deficiency. Am J Med Genet. 1987 Feb;26(2):377-83. [PubMed:3812589 ]
HMDB0003429Cob(I)alamin18534-66-2ThumbC62H89CoN13O14P1330.378
1329.572151		Not Available
HMDB0003966Selenomethionine3211-76-5ThumbC5H11NO2Se196.11
196.995500429		Not Available
HMDB0004119Selenohomocysteine29475-60-3ThumbC4H9NO2Se182.092
182.979851		Not Available
HMDB0006316Cob(II)alamin14463-33-3ThumbC62H89CoN13O14P1330.377
1329.571053		Not Available
HMDB00121775-Methyltetrahydropteroyltri-L-glutamic acid133321-34-3ThumbC30H39N9O12717.6838
717.271817757		Not Available
HMDB0012290Tetrahydropteroyltri-L-glutamic acid88903-89-3ThumbC29H37N9O12703.6572
703.256167693		Not Available
HMDB0015532Zinc7440-66-6ThumbZn65.409
63.929146578		Not Available
Displaying all 19 metabolite protein links