Hmdb loader

HMDB0001388 (alpha-Linolenic acid) Protein Associations

Displaying metabolite protein links 1 - 25 of 30 in total
HMDBP ID Name UniProt ID Gene Name Locus Type References
HMDBP00058Calcium-dependent phospholipase A2P39877 PLA2G51p36-p34UnknownNot Available
HMDBP00059Group IIF secretory phospholipase A2Q9BZM2 PLA2G2F1p35UnknownNot Available
HMDBP00060Cytosolic phospholipase A2P47712 PLA2G4A1q25UnknownNot Available
HMDBP00061Phospholipase A2P04054 PLA2G1B12q23-q24.1UnknownNot Available
HMDBP00062Group XIIB secretory phospholipase A2-like proteinQ9BX93 PLA2G12BUnknownNot Available
HMDBP00063Group 10 secretory phospholipase A2O15496 PLA2G1016p13.1-p12UnknownNot Available
HMDBP00065Group IIE secretory phospholipase A2Q9NZK7 PLA2G2E1p36.13UnknownNot Available
HMDBP00067Group XIIA secretory phospholipase A2Q9BZM1 PLA2G12A4q25UnknownNot Available
HMDBP0006885/88 kDa calcium-independent phospholipase A2O60733 PLA2G622q13.1UnknownNot Available
HMDBP00072Phospholipase A2, membrane associatedP14555 PLA2G2A1p35UnknownNot Available
HMDBP00073Group IID secretory phospholipase A2Q9UNK4 PLA2G2D1p36.12UnknownNot Available
HMDBP00529Cytosolic phospholipase A2 gammaQ9UP65 PLA2G4C19q13.3UnknownNot Available
HMDBP00532Group 3 secretory phospholipase A2Q9NZ20 PLA2G322q12.2UnknownNot Available
HMDBP00549Bile acid-CoA:amino acid N-acyltransferaseQ14032 BAAT9q22.3EnzymeNot Available
HMDBP01046Cytosolic acyl coenzyme A thioester hydrolaseO00154 ACOT71p36EnzymeNot Available
HMDBP01047Acyl-coenzyme A thioesterase 2, mitochondrialP49753 ACOT214q24.3EnzymeNot Available
HMDBP01048Acyl-coenzyme A thioesterase 4Q8N9L9 ACOT414q24.3EnzymeNot Available
HMDBP01049Acyl-coenzyme A thioesterase 8O14734 ACOT820q13.12EnzymeNot Available
HMDBP02234Transient receptor potential cation channel subfamily V member 1Q8NER1 TRPV117p13.2Unknown
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
HMDBP02649Fatty acid desaturase 1O60427 FADS111q12.2-q13.1Unknown
  1. Xiang M, Rahman MA, Ai H, Li X, Harbige LS: Diet and gene expression: delta-5 and delta-6 desaturases in healthy Chinese and European subjects. Ann Nutr Metab. 2006;50(6):492-8. Epub 2006 Sep 19. [PubMed:16988497 ]
  2. Descomps B, Rodriguez A: [Essential fatty acids and prematurity: a triple experimental approach]. C R Seances Soc Biol Fil. 1995;189(5):781-96. [PubMed:8673626 ]
  3. Hoffman DR, DeMar JC, Heird WC, Birch DG, Anderson RE: Impaired synthesis of DHA in patients with X-linked retinitis pigmentosa. J Lipid Res. 2001 Sep;42(9):1395-401. [PubMed:11518758 ]
  4. Maniongui C, Blond JP, Ulmann L, Durand G, Poisson JP, Bezard J: Age-related changes in delta 6 and delta 5 desaturase activities in rat liver microsomes. Lipids. 1993 Apr;28(4):291-7. [PubMed:8487621 ]
  5. Mohan IK, Das UN: Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus. Prostaglandins Leukot Essent Fatty Acids. 2000 Jan;62(1):35-46. [PubMed:10765977 ]
HMDBP03051Sodium/calcium exchanger 1P32418 SLC8A12p23-p22Unknown
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
  3. Ander BP, Hurtado C, Raposo CS, Maddaford TG, Deniset JF, Hryshko LV, Pierce GN, Lukas A: Differential sensitivities of the NCX1.1 and NCX1.3 isoforms of the Na+-Ca2+ exchanger to alpha-linolenic acid. Cardiovasc Res. 2007 Jan 15;73(2):395-403. Epub 2006 Sep 23. [PubMed:17059813 ]
HMDBP03232Fatty acid desaturase 2O95864 FADS211q12.2Unknown
  1. Ge L, Gordon JS, Hsuan C, Stenn K, Prouty SM: Identification of the delta-6 desaturase of human sebaceous glands: expression and enzyme activity. J Invest Dermatol. 2003 May;120(5):707-14. [PubMed:12713571 ]
  2. Xiang M, Rahman MA, Ai H, Li X, Harbige LS: Diet and gene expression: delta-5 and delta-6 desaturases in healthy Chinese and European subjects. Ann Nutr Metab. 2006;50(6):492-8. Epub 2006 Sep 19. [PubMed:16988497 ]
  3. Portolesi R, Powell BC, Gibson RA: Competition between 24:5n-3 and ALA for Delta 6 desaturase may limit the accumulation of DHA in HepG2 cell membranes. J Lipid Res. 2007 Jul;48(7):1592-8. Epub 2007 Apr 4. [PubMed:17409318 ]
  4. Baylin A, Ruiz-Narvaez E, Kraft P, Campos H: alpha-Linolenic acid, Delta6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction. Am J Clin Nutr. 2007 Feb;85(2):554-60. [PubMed:17284757 ]
  5. Li MC, Bu YP, Wang GK, Hu GW, Xing LJ: [Heteologous expression of Mortierella isabellina delta6 -fatty acid desaturase gene in soybean]. Yi Chuan Xue Bao. 2004 Aug;31(8):858-63. [PubMed:15481543 ]
  6. Tan L, Meesapyodsuk D, Qiu X: Molecular analysis of 6 desaturase and 6 elongase from Conidiobolus obscurus in the biosynthesis of eicosatetraenoic acid, a omega3 fatty acid with nutraceutical potentials. Appl Microbiol Biotechnol. 2011 Apr;90(2):591-601. doi: 10.1007/s00253-010-3060-y. Epub 2011 Jan 6. [PubMed:21210105 ]
HMDBP04479Elongation of very long chain fatty acids protein 4Q9GZR5 ELOVL46q14Enzyme
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
HMDBP07301Phospholipase B1, membrane-associatedQ6P1J6 PLB12p23.2UnknownNot Available
HMDBP07863Cytosolic phospholipase A2 deltaQ86XP0 PLA2G4D15q15.1UnknownNot Available
Displaying metabolite protein links 1 - 25 of 30 in total