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Identification Taxonomy Ontology Physical properties Spectra Biological properties Concentrations Links References enzymes (16) Show 16 proteins XML

Record Information

Version

5.0

Status

Detected but not Quantified

Creation Date

2005-11-16 15:48:42 UTC

Update Date

2021-09-14 15:18:55 UTC

HMDB ID

HMDB0001078

Secondary Accession Numbers

HMDB01078

Metabolite Identification

Common Name

Mannose 6-phosphate

Description

Mannose 6-phosphate, also known as alpha-D-mannose-6-p or man-6-p, belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups. Mannose 6-phosphate exists in all eukaryotes, ranging from yeast to humans. Within humans, mannose 6-phosphate participates in a number of enzymatic reactions. In particular, mannose 6-phosphate can be converted into fructose 6-phosphate through its interaction with the enzyme mannose-6-phosphate isomerase. In addition, mannose 6-phosphate can be biosynthesized from D-mannose through the action of the enzyme hexokinase-1. Mannose 6-phosphate is a potent competitive inhibitor of pinocytosis of human platelet beta-glucuronidase and it is a necessary component of the recognition marker on the enzyme for pinocytosis by human fibroblasts as well (PMID 908752 ). In humans, mannose 6-phosphate is involved in fructose intolerance, hereditary.

Structure

MOL 3D MOL SDF 3D SDF PDB 3D PDB SMILES InChI

HMDB0001078
     RDKit          3D
Mannose 6-phosphate
 29 29  0  0  0  0  0  0  0  0999 V2000
    4.0933    1.9361    2.0961 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5449    1.0710    0.9859 P   0  0  0  0  0  5  0  0  0  0  0  0
    4.0994    1.7226   -0.4713 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1152   -0.5125    1.1478 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8474    1.1203    0.9329 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3998   -0.1809    0.8659 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0060   -0.3473    0.4086 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.9363   -0.1578    1.4328 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2215   -0.3534    0.9760 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.0080    0.7849    1.0013 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3083   -0.9441   -0.3999 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.6619   -0.9349   -0.7723 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5494   -0.1679   -1.4390 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.3437    0.6926   -2.1700 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4176    0.5554   -0.7170 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.6103    0.8998   -1.5707 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2914    0.9613   -1.0706 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.0933   -0.4439    1.2699 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4965   -0.6166    1.8887 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0893   -0.7598    0.2249 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1252   -1.4146    0.0918 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6990   -1.0899    1.6707 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8016    0.7172    1.5736 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0212   -2.0137   -0.3553 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2043   -0.3960   -0.1467 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0774   -0.9085   -2.1323 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5312    0.2896   -3.0651 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8653    1.5016   -0.3281 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0972    0.1290   -1.9285 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0
  2  3  1  0
  2  4  1  0
  2  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
  9 11  1  0
 11 12  1  0
 11 13  1  0
 13 14  1  0
 13 15  1  0
 15 16  1  0
 15  7  1  0
  3 17  1  0
  4 18  1  0
  6 19  1  0
  6 20  1  0
  7 21  1  6
  9 22  1  1
 10 23  1  0
 11 24  1  1
 12 25  1  0
 13 26  1  6
 14 27  1  0
 15 28  1  1
 16 29  1  0
M  END


  Mrv1652309042000172D          

 16 16  0  0  1  0            999 V2000
   -1.9884    0.3079    0.0000 P   0  0  0  0  0  0  0  0  0  0  0  0
   -1.1595    0.3042    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.8171    0.3079    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9884    1.1329    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.9959   -0.5208    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.5247    0.8364    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1825    0.4258    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.1825   -0.3992    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.9010    0.8364    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    0.9010   -0.8174    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.5247   -0.8174    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.6233    0.4258    0.0000 C   0  0  2  0  0  0  0  0  0  0  0  0
    1.6233   -0.3992    0.0000 C   0  0  1  0  0  0  0  0  0  0  0  0
    0.9010   -1.6424    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3381    0.8364    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
    2.3381   -0.8174    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  1  0  0  0  0
  1  3  1  0  0  0  0
  1  4  1  0  0  0  0
  1  5  2  0  0  0  0
  2  6  1  0  0  0  0
  7  6  1  1  0  0  0
  7  8  1  0  0  0  0
  7  9  1  0  0  0  0
  8 10  1  0  0  0  0
  8 11  1  6  0  0  0
  9 12  1  0  0  0  0
 10 13  1  0  0  0  0
 10 14  1  1  0  0  0
 12 15  1  1  0  0  0
 13 16  1  1  0  0  0
 12 13  1  0  0  0  0
M  END
> <DATABASE_ID>
HMDB0001078

> <DATABASE_NAME>
hmdb

> <SMILES>
O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O

> <INCHI_IDENTIFIER>
InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5+,6-/m1/s1

> <INCHI_KEY>
NBSCHQHZLSJFNQ-RWOPYEJCSA-N

> <FORMULA>
C6H13O9P

> <MOLECULAR_WEIGHT>
260.1358

> <EXACT_MASS>
260.029718526

> <JCHEM_ACCEPTOR_COUNT>
8

> <JCHEM_ATOM_COUNT>
29

> <JCHEM_AVERAGE_POLARIZABILITY>
20.99390478641751

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
6

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
{[(2R,3S,4S,5S,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid

> <ALOGPS_LOGP>
-2.06

> <JCHEM_LOGP>
-3.056105249333333

> <ALOGPS_LOGS>
-0.92

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
1

> <JCHEM_PHYSIOLOGICAL_CHARGE>
-2

> <JCHEM_PKA>
6.248752256962443

> <JCHEM_PKA_STRONGEST_ACIDIC>
1.222936327751123

> <JCHEM_PKA_STRONGEST_BASIC>
-3.64935696086094

> <JCHEM_POLAR_SURFACE_AREA>
156.91

> <JCHEM_REFRACTIVITY>
46.796299999999995

> <JCHEM_ROTATABLE_BOND_COUNT>
3

> <JCHEM_RULE_OF_FIVE>
0

> <ALOGPS_SOLUBILITY>
3.14e+01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
mannose 6 phosphate

> <JCHEM_VEBER_RULE>
0

$$$$

HMDB0001078
     RDKit          3D
Mannose 6-phosphate
 29 29  0  0  0  0  0  0  0  0999 V2000
    4.0933    1.9361    2.0961 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5449    1.0710    0.9859 P   0  0  0  0  0  5  0  0  0  0  0  0
    4.0994    1.7226   -0.4713 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1152   -0.5125    1.1478 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8474    1.1203    0.9329 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3998   -0.1809    0.8659 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0060   -0.3473    0.4086 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.9363   -0.1578    1.4328 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2215   -0.3534    0.9760 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.0080    0.7849    1.0013 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3083   -0.9441   -0.3999 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.6619   -0.9349   -0.7723 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5494   -0.1679   -1.4390 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.3437    0.6926   -2.1700 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4176    0.5554   -0.7170 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.6103    0.8998   -1.5707 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2914    0.9613   -1.0706 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.0933   -0.4439    1.2699 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4965   -0.6166    1.8887 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0893   -0.7598    0.2249 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1252   -1.4146    0.0918 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6990   -1.0899    1.6707 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8016    0.7172    1.5736 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0212   -2.0137   -0.3553 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2043   -0.3960   -0.1467 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0774   -0.9085   -2.1323 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5312    0.2896   -3.0651 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8653    1.5016   -0.3281 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0972    0.1290   -1.9285 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0
  2  3  1  0
  2  4  1  0
  2  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
  9 11  1  0
 11 12  1  0
 11 13  1  0
 13 14  1  0
 13 15  1  0
 15 16  1  0
 15  7  1  0
  3 17  1  0
  4 18  1  0
  6 19  1  0
  6 20  1  0
  7 21  1  6
  9 22  1  1
 10 23  1  0
 11 24  1  1
 12 25  1  0
 13 26  1  6
 14 27  1  0
 15 28  1  1
 16 29  1  0
M  END

HEADER    PROTEIN                                 04-SEP-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   04-SEP-20         0                                  
HETATM    1  P   UNK     0      -3.712   0.575   0.000  0.00  0.00           P+0
HETATM    2  O   UNK     0      -2.164   0.568   0.000  0.00  0.00           O+0
HETATM    3  O   UNK     0      -5.259   0.575   0.000  0.00  0.00           O+0
HETATM    4  O   UNK     0      -3.712   2.115   0.000  0.00  0.00           O+0
HETATM    5  O   UNK     0      -3.726  -0.972   0.000  0.00  0.00           O+0
HETATM    6  C   UNK     0      -0.979   1.561   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0       0.341   0.795   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0       0.341  -0.745   0.000  0.00  0.00           C+0
HETATM    9  O   UNK     0       1.682   1.561   0.000  0.00  0.00           O+0
HETATM   10  C   UNK     0       1.682  -1.526   0.000  0.00  0.00           C+0
HETATM   11  O   UNK     0      -0.979  -1.526   0.000  0.00  0.00           O+0
HETATM   12  C   UNK     0       3.030   0.795   0.000  0.00  0.00           C+0
HETATM   13  C   UNK     0       3.030  -0.745   0.000  0.00  0.00           C+0
HETATM   14  O   UNK     0       1.682  -3.066   0.000  0.00  0.00           O+0
HETATM   15  O   UNK     0       4.364   1.561   0.000  0.00  0.00           O+0
HETATM   16  O   UNK     0       4.364  -1.526   0.000  0.00  0.00           O+0
CONECT    1    2    3    4    5                                             
CONECT    2    1    6                                                       
CONECT    3    1                                                            
CONECT    4    1                                                            
CONECT    5    1                                                            
CONECT    6    2    7                                                       
CONECT    7    6    8    9                                                  
CONECT    8    7   10   11                                                  
CONECT    9    7   12                                                       
CONECT   10    8   13   14                                                  
CONECT   11    8                                                            
CONECT   12    9   15   13                                                  
CONECT   13   10   16   12                                                  
CONECT   14   10                                                            
CONECT   15   12                                                            
CONECT   16   13                                                            
MASTER        0    0    0    0    0    0    0    0   16    0   32    0
END

COMPND    HMDB0001078
HETATM    1  O1  UNL     1       4.093   1.936   2.096  1.00  0.00           O  
HETATM    2  P1  UNL     1       3.545   1.071   0.986  1.00  0.00           P  
HETATM    3  O2  UNL     1       4.099   1.723  -0.471  1.00  0.00           O  
HETATM    4  O3  UNL     1       4.115  -0.513   1.148  1.00  0.00           O  
HETATM    5  O4  UNL     1       1.847   1.120   0.933  1.00  0.00           O  
HETATM    6  C1  UNL     1       1.400  -0.181   0.866  1.00  0.00           C  
HETATM    7  C2  UNL     1      -0.006  -0.347   0.409  1.00  0.00           C  
HETATM    8  O5  UNL     1      -0.936  -0.158   1.433  1.00  0.00           O  
HETATM    9  C3  UNL     1      -2.222  -0.353   0.976  1.00  0.00           C  
HETATM   10  O6  UNL     1      -3.008   0.785   1.001  1.00  0.00           O  
HETATM   11  C4  UNL     1      -2.308  -0.944  -0.400  1.00  0.00           C  
HETATM   12  O7  UNL     1      -3.662  -0.935  -0.772  1.00  0.00           O  
HETATM   13  C5  UNL     1      -1.549  -0.168  -1.439  1.00  0.00           C  
HETATM   14  O8  UNL     1      -2.344   0.693  -2.170  1.00  0.00           O  
HETATM   15  C6  UNL     1      -0.418   0.555  -0.717  1.00  0.00           C  
HETATM   16  O9  UNL     1       0.610   0.900  -1.571  1.00  0.00           O  
HETATM   17  H1  UNL     1       4.291   0.961  -1.071  1.00  0.00           H  
HETATM   18  H2  UNL     1       5.093  -0.444   1.270  1.00  0.00           H  
HETATM   19  H3  UNL     1       1.496  -0.617   1.889  1.00  0.00           H  
HETATM   20  H4  UNL     1       2.089  -0.760   0.225  1.00  0.00           H  
HETATM   21  H5  UNL     1      -0.125  -1.415   0.092  1.00  0.00           H  
HETATM   22  H6  UNL     1      -2.699  -1.090   1.671  1.00  0.00           H  
HETATM   23  H7  UNL     1      -3.802   0.717   1.574  1.00  0.00           H  
HETATM   24  H8  UNL     1      -2.021  -2.014  -0.355  1.00  0.00           H  
HETATM   25  H9  UNL     1      -4.204  -0.396  -0.147  1.00  0.00           H  
HETATM   26  H10 UNL     1      -1.077  -0.908  -2.132  1.00  0.00           H  
HETATM   27  H11 UNL     1      -2.531   0.290  -3.065  1.00  0.00           H  
HETATM   28  H12 UNL     1      -0.865   1.502  -0.328  1.00  0.00           H  
HETATM   29  H13 UNL     1       1.097   0.129  -1.928  1.00  0.00           H  
CONECT    1    2    2
CONECT    2    3    4    5
CONECT    3   17
CONECT    4   18
CONECT    5    6
CONECT    6    7   19   20
CONECT    7    8   15   21
CONECT    8    9
CONECT    9   10   11   22
CONECT   10   23
CONECT   11   12   13   24
CONECT   12   25
CONECT   13   14   15   26
CONECT   14   27
CONECT   15   16   28
CONECT   16   29
END

HMDB0001078
     RDKit          3D
Mannose 6-phosphate
 29 29  0  0  0  0  0  0  0  0999 V2000
    4.0933    1.9361    2.0961 O   0  0  0  0  0  0  0  0  0  0  0  0
    3.5449    1.0710    0.9859 P   0  0  0  0  0  5  0  0  0  0  0  0
    4.0994    1.7226   -0.4713 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.1152   -0.5125    1.1478 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.8474    1.1203    0.9329 O   0  0  0  0  0  0  0  0  0  0  0  0
    1.3998   -0.1809    0.8659 C   0  0  0  0  0  0  0  0  0  0  0  0
   -0.0060   -0.3473    0.4086 C   0  0  1  0  0  0  0  0  0  0  0  0
   -0.9363   -0.1578    1.4328 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.2215   -0.3534    0.9760 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.0080    0.7849    1.0013 O   0  0  0  0  0  0  0  0  0  0  0  0
   -2.3083   -0.9441   -0.3999 C   0  0  1  0  0  0  0  0  0  0  0  0
   -3.6619   -0.9349   -0.7723 O   0  0  0  0  0  0  0  0  0  0  0  0
   -1.5494   -0.1679   -1.4390 C   0  0  1  0  0  0  0  0  0  0  0  0
   -2.3437    0.6926   -2.1700 O   0  0  0  0  0  0  0  0  0  0  0  0
   -0.4176    0.5554   -0.7170 C   0  0  2  0  0  0  0  0  0  0  0  0
    0.6103    0.8998   -1.5707 O   0  0  0  0  0  0  0  0  0  0  0  0
    4.2914    0.9613   -1.0706 H   0  0  0  0  0  0  0  0  0  0  0  0
    5.0933   -0.4439    1.2699 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.4965   -0.6166    1.8887 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.0893   -0.7598    0.2249 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.1252   -1.4146    0.0918 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.6990   -1.0899    1.6707 H   0  0  0  0  0  0  0  0  0  0  0  0
   -3.8016    0.7172    1.5736 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.0212   -2.0137   -0.3553 H   0  0  0  0  0  0  0  0  0  0  0  0
   -4.2043   -0.3960   -0.1467 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.0774   -0.9085   -2.1323 H   0  0  0  0  0  0  0  0  0  0  0  0
   -2.5312    0.2896   -3.0651 H   0  0  0  0  0  0  0  0  0  0  0  0
   -0.8653    1.5016   -0.3281 H   0  0  0  0  0  0  0  0  0  0  0  0
    1.0972    0.1290   -1.9285 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0
  2  3  1  0
  2  4  1  0
  2  5  1  0
  5  6  1  0
  6  7  1  0
  7  8  1  0
  8  9  1  0
  9 10  1  0
  9 11  1  0
 11 12  1  0
 11 13  1  0
 13 14  1  0
 13 15  1  0
 15 16  1  0
 15  7  1  0
  3 17  1  0
  4 18  1  0
  6 19  1  0
  6 20  1  0
  7 21  1  6
  9 22  1  1
 10 23  1  0
 11 24  1  1
 12 25  1  0
 13 26  1  6
 14 27  1  0
 15 28  1  1
 16 29  1  0
M  END

View in JSmol View Stereo Labels

Synonyms

Value	Source
Mannose 6-phosphoric acid	Generator
alpha-D-Mannose-6-p	HMDB
alpha-D-Mannose-6-phosphate	HMDB
alpha-delta-Mannose-6-p	HMDB
alpha-delta-Mannose-6-phosphate	HMDB
D-Mannose 6-phosphate	HMDB
delta-Mannose 6-phosphate	HMDB
Man-6-p	HMDB
Mannose-6-phosphate	HMDB
Mannose-6-phosphate dilithium salt	HMDB
Mannose-6-phosphate disodium salt	HMDB
Mannose-6-phosphate sodium salt, (D)-isomer	HMDB

Chemical Formula

C₆H₁₃O₉P

Average Molecular Weight

260.1358

Monoisotopic Molecular Weight

260.029718526

IUPAC Name

{[(2R,3S,4S,5S,6R)-3,4,5,6-tetrahydroxyoxan-2-yl]methoxy}phosphonic acid

Traditional Name

mannose 6 phosphate

CAS Registry Number

3672-15-9

SMILES

O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O

InChI Identifier

InChI=1S/C6H13O9P/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8/h2-10H,1H2,(H2,11,12,13)/t2-,3-,4+,5+,6-/m1/s1

InChI Key

NBSCHQHZLSJFNQ-RWOPYEJCSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as hexose phosphates. These are carbohydrate derivatives containing a hexose substituted by one or more phosphate groups.

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Carbohydrates and carbohydrate conjugates

Direct Parent

Hexose phosphates

Alternative Parents

Substituents

Hexose phosphate
Monosaccharide phosphate
Monoalkyl phosphate
Organic phosphoric acid derivative
Alkyl phosphate
Oxane
Phosphoric acid ester
Hemiacetal
Secondary alcohol
Oxacycle
Organoheterocyclic compound
Polyol
Hydrocarbon derivative
Alcohol
Organic oxide
Aliphatic heteromonocyclic compound

Molecular Framework

Aliphatic heteromonocyclic compounds

External Descriptors

D-mannopyranose 6-phosphate (CHEBI:49728 )

Ontology

Physiological effect

Not Available

Disposition

Biological location

Testicle (HMDB: HMDB0001078)

Cell

Fibroblast

Fibroblast (HMDB: HMDB0001078)

Fibroblasts (HMDB: HMDB0001078)

Organ

Excreta

Biofluid or Excreta

Feces (PMID: 25037050)

Cellular substructure

Cytoplasm (HMDB: HMDB0001078)

Source

Endogenous

Endogenous (HMDB: HMDB0001078)

Greylag goose (FooDB: FOOD00368)
Guinea hen (FooDB: FOOD00373)
Ostrich (FooDB: FOOD00422)
Velvet duck (FooDB: FOOD00427)
Pheasant (FooDB: FOOD00430)
Squab (FooDB: FOOD00481)
Turkey (FooDB: FOOD00494)
Quail (FooDB: FOOD00541)
Anatidae (FooDB: FOOD00576)
Rock ptarmigan (FooDB: FOOD00597)
Columbidae (Dove, Pigeon) (FooDB: FOOD00610)
Chicken (FooDB: FOOD00329)
Mallard duck (FooDB: FOOD00353)
Emu (FooDB: FOOD00360)

Equine

Horse (FooDB: FOOD00378)

Lagomorph

Ovis

Sheep (Mutton, Lamb) (FooDB: FOOD00473)

Bovine

Venison

Deer (FooDB: FOOD00524)
Mule deer (FooDB: FOOD00348)
Elk (FooDB: FOOD00359)

Caprae

Domestic goat (FooDB: FOOD00529)

Swine

Domestic pig (FooDB: FOOD00536)
Wild boar (FooDB: FOOD00307)

Herb and spice mixture

Curry powder (FooDB: FOOD00678)

Vegetable

Cabbage

Onion-family vegetable

Root vegetable

Shoot vegetable

Leaf vegetable

Common beet (FooDB: FOOD00025)
Endive (FooDB: FOOD00048)
Rocket salad (ssp.) (FooDB: FOOD00077)
Swamp cabbage (FooDB: FOOD00091)
Lettuce (FooDB: FOOD00095)
Garden cress (FooDB: FOOD00099)
Spinach (FooDB: FOOD00178)
Swiss chard (FooDB: FOOD00237)
Chicory leaves (FooDB: FOOD00250)
Garland chrysanthemum (FooDB: FOOD00333)
Corn salad (FooDB: FOOD00340)
Jute (FooDB: FOOD00389)
Lambsquarters (FooDB: FOOD00394)
Malabar spinach (FooDB: FOOD00404)
New Zealand spinach (FooDB: FOOD00415)
Yautia (FooDB: FOOD00510)
Ostrich fern (FooDB: FOOD00556)
Romaine lettuce (FooDB: FOOD00888)
Iceberg lettuce (FooDB: FOOD00973)
Pea shoots (FooDB: FOOD00975)
Yau choy (FooDB: FOOD00976)
Water spinach (FooDB: FOOD00977)

Fruit vegetable

Pepper (FooDB: FOOD00040)
Olive (FooDB: FOOD00121)
Avocado (FooDB: FOOD00130)
Garden tomato (FooDB: FOOD00171)
Cherry tomato (FooDB: FOOD00172)
Garden tomato (var.) (FooDB: FOOD00173)
Eggplant (FooDB: FOOD00174)
Pepper (C. baccatum) (FooDB: FOOD00231)
Pepper (C. chinense) (FooDB: FOOD00232)
Pepper (Capsicum) (FooDB: FOOD00233)
Groundcherry (FooDB: FOOD00371)
Pepper (C. frutescens) (FooDB: FOOD00428)
Mexican groundcherry (FooDB: FOOD00491)
Pepper (C. pubescens) (FooDB: FOOD00849)
Green bell pepper (FooDB: FOOD00877)
Yellow bell pepper (FooDB: FOOD00878)
Orange bell pepper (FooDB: FOOD00879)
Red bell pepper (FooDB: FOOD00880)
Italian sweet red pepper (FooDB: FOOD00881)
Jalapeno pepper (FooDB: FOOD00955)
Cubanelle pepper (FooDB: FOOD00971)

Tuber

Stalk vegetable

Other vegetable

Giant butterbur (FooDB: FOOD00314)
Carob (FooDB: FOOD00321)
Chinese water chestnut (FooDB: FOOD00332)
Horseradish tree (FooDB: FOOD00379)
Sacred lotus (FooDB: FOOD00402)
Nopal (FooDB: FOOD00416)
Okra (FooDB: FOOD00420)
Sesbania flower (FooDB: FOOD00469)
Agave (FooDB: FOOD00563)
Narrowleaf cattail (FooDB: FOOD00564)
Heart of palm (FooDB: FOOD00718)
Tree fern (FooDB: FOOD00797)

Mushroom

Castanospermum australe (FooDB: FOOD00893)
Gentiana lutea (FooDB: FOOD00894)
Juniperus communis (FooDB: FOOD00895)
Albizia gummifera (FooDB: FOOD00896)

Fruit

Tropical fruit

Citrus

Lime (FooDB: FOOD00053)
Lemon (FooDB: FOOD00054)
Pummelo (FooDB: FOOD00055)
Mandarin orange (Clementine, Tangerine) (FooDB: FOOD00056)
Sweet orange (FooDB: FOOD00057)
Grapefruit/Pummelo hybrid (FooDB: FOOD00255)
Grapefruit (FooDB: FOOD00256)
Persian lime (FooDB: FOOD00543)
Sour orange (FooDB: FOOD00918)
Mikan (FooDB: FOOD00932)
Clementine (FooDB: FOOD00959)

Pome

Berry

Black crowberry (FooDB: FOOD00075)
Strawberry (FooDB: FOOD00083)
Black huckleberry (FooDB: FOOD00084)
Sea-buckthornberry (FooDB: FOOD00087)
Mulberry (FooDB: FOOD00116)
Black mulberry (FooDB: FOOD00117)
Black chokeberry (FooDB: FOOD00136)
Blackcurrant (FooDB: FOOD00155)
Redcurrant (FooDB: FOOD00156)
Gooseberry (FooDB: FOOD00157)
Cloudberry (FooDB: FOOD00161)
Red raspberry (FooDB: FOOD00162)
Black raspberry (FooDB: FOOD00163)
Black elderberry (FooDB: FOOD00166)
Rowanberry (FooDB: FOOD00176)
Vaccinium (Blueberry, Cranberry, Huckleberry) (FooDB: FOOD00188)
Lowbush blueberry (FooDB: FOOD00189)
Sparkleberry (FooDB: FOOD00190)
Highbush blueberry (FooDB: FOOD00191)
American cranberry (FooDB: FOOD00192)
Bilberry (FooDB: FOOD00193)
Lingonberry (FooDB: FOOD00194)
Muscadine grape (FooDB: FOOD00203)
Common grape (FooDB: FOOD00204)
Arctic blackberry (FooDB: FOOD00207)
Bayberry (FooDB: FOOD00209)
Elliott's blueberry (FooDB: FOOD00210)
Canada blueberry (FooDB: FOOD00211)
Bog bilberry (FooDB: FOOD00212)
Buffalo currant (FooDB: FOOD00213)
European cranberry (FooDB: FOOD00217)
Deerberry (FooDB: FOOD00218)
Cascade huckleberry (FooDB: FOOD00220)
Oval-leaf huckleberry (FooDB: FOOD00221)
Evergreen huckleberry (FooDB: FOOD00222)
Red huckleberry (FooDB: FOOD00223)
Summer grape (FooDB: FOOD00227)
Fox grape (FooDB: FOOD00228)
Half-highbush blueberry (FooDB: FOOD00248)
Jostaberry (FooDB: FOOD00257)
Sweet rowanberry (FooDB: FOOD00265)
Skunk currant (FooDB: FOOD00267)
Squashberry (FooDB: FOOD00344)
Elderberry (FooDB: FOOD00358)
Grape (FooDB: FOOD00369)
Alaska blueberry (FooDB: FOOD00380)
Loganberry (FooDB: FOOD00400)
Ohelo berry (FooDB: FOOD00419)
Salmonberry (FooDB: FOOD00456)
Strawberry guava (FooDB: FOOD00482)
Boysenberry (FooDB: FOOD00542)
Chinese bayberry (FooDB: FOOD00852)
Saskatoon berry (FooDB: FOOD00884)
Nanking cherry (FooDB: FOOD00885)
Rabbiteye blueberry (FooDB: FOOD00898)
Blackberry (FooDB: FOOD00906)
Partridge berry (FooDB: FOOD00931)
Green grape (FooDB: FOOD00964)
Red grape (FooDB: FOOD00965)
Black plum (FooDB: FOOD00966)
Black raisin (FooDB: FOOD00968)
Chinese plum (FooDB: FOOD00978)
Green plum (FooDB: FOOD00979)
Wampee (FooDB: FOOD00980)
Goji (FooDB: FOOD00982)
Monk fruit (FooDB: FOOD00983)
Hawthorn (FooDB: FOOD00985)
Lantern fruit (FooDB: FOOD00986)
Cape gooseberry (FooDB: FOOD00988)

Other fruit

Fig (FooDB: FOOD00081)
Date (FooDB: FOOD00135)
Jujube (FooDB: FOOD00388)

Drupe

Prunus (Cherry, Plum) (FooDB: FOOD00143)
Apricot (FooDB: FOOD00144)
Sweet cherry (FooDB: FOOD00145)
Sour cherry (FooDB: FOOD00146)
European plum (FooDB: FOOD00147)
Peach (FooDB: FOOD00149)
Nectarine (FooDB: FOOD00229)
Peach (var.) (FooDB: FOOD00230)
Common chokecherry (FooDB: FOOD00562)

Nut

Cashew nut (FooDB: FOOD00011)
Peanut (FooDB: FOOD00016)
Brazil nut (FooDB: FOOD00024)
Pecan nut (FooDB: FOOD00044)
Chestnut (FooDB: FOOD00045)
Common hazelnut (FooDB: FOOD00062)
Black walnut (FooDB: FOOD00093)
Common walnut (FooDB: FOOD00094)
Pine nut (FooDB: FOOD00138)
Pistachio (FooDB: FOOD00140)
Almond (FooDB: FOOD00148)
Macadamia nut (M. tetraphylla) (FooDB: FOOD00225)
Japanese walnut (FooDB: FOOD00240)
Acorn (FooDB: FOOD00282)
Beech nut (FooDB: FOOD00299)
Butternut (FooDB: FOOD00316)
Chinese chestnut (FooDB: FOOD00331)
European chestnut (FooDB: FOOD00363)
Hazelnut (FooDB: FOOD00376)
Hickory nut (FooDB: FOOD00377)
Japanese chestnut (FooDB: FOOD00385)
Pili nut (FooDB: FOOD00432)
Colorado pinyon (FooDB: FOOD00433)
Macadamia nut (FooDB: FOOD00525)
Walnut (FooDB: FOOD00608)

Cereal and cereal product

Cereal

Cereal product

Pasta (FooDB: FOOD00273)
Bulgur (FooDB: FOOD00741)
Semolina (FooDB: FOOD00745)
Flour (FooDB: FOOD00799)

Dough

Sourdough (FooDB: FOOD00275)

Leavened bread

Flat bread

Other bread

Potato bread (FooDB: FOOD00811)

Sweet bread

Raisin bread (FooDB: FOOD00817)

Pulse

Pea

Lentil

Lentils (FooDB: FOOD00098)

Other pulse

Lupine (FooDB: FOOD00104)
White lupine (FooDB: FOOD00403)

Bean

Green lentil (FooDB: FOOD00970)

Gourd

Watermelon (FooDB: FOOD00052)
Muskmelon (FooDB: FOOD00064)
Cucumber (FooDB: FOOD00065)
Cucurbita (FooDB: FOOD00066)
Bitter gourd (FooDB: FOOD00115)
Winter squash (FooDB: FOOD00283)
Butternut squash (FooDB: FOOD00317)
Calabash (FooDB: FOOD00318)
Chayote (FooDB: FOOD00325)
Towel gourd (FooDB: FOOD00492)
Wax gourd (FooDB: FOOD00499)
Tinda (FooDB: FOOD00559)
Horned melon (FooDB: FOOD00761)
Sunburst squash (pattypan squash) (FooDB: FOOD00874)
Green zucchini (FooDB: FOOD00875)
Yellow zucchini (FooDB: FOOD00876)
Japanese pumpkin (FooDB: FOOD00886)
Acorn squash (FooDB: FOOD00972)
Cantaloupe melon (FooDB: FOOD00984)

Coffee and coffee product

Coffee

Arabica coffee (FooDB: FOOD00059)
Robusta coffee (FooDB: FOOD00060)

Soy

Soy bean (FooDB: FOOD00085)

Soy product

Soy sauce (FooDB: FOOD00694)
Miso (FooDB: FOOD00695)
Tofu (FooDB: FOOD00696)
Soy milk (FooDB: FOOD00736)
Soy cream (FooDB: FOOD00784)

Dish

Other dish

Taco shell (FooDB: FOOD00991)
Tostada shell (FooDB: FOOD00992)

Tea

Herbal tea

Hibiscus tea (FooDB: FOOD00723)
Greenthread tea (FooDB: FOOD00820)

Baking good

Wrapper

Wonton wrapper (FooDB: FOOD00818)

Process

Naturally occurring process

Biological process

Biochemical pathway

Metabolic pathway

Fructose and Mannose Degradation (HMDB: HMDB0001078)
2-O-alpha-Mannosyl-D-glycerate Degradation (PathBank: SMP0002108)
Mannose Metabolism (PathBank: SMP0002315)
Amino Sugar and Nucleotide Sugar Metabolism (PathBank: SMP0002331)

Fructose and Mannose Degradation (HMDB: HMDB0001078)

Disease pathway

Fructose Intolerance, Hereditary (PathBank: SMP0000725)
Fructosuria (PathBank: SMP0000561)

Role

Not Available

Physical Properties

State

Solid

Experimental Molecular Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	Not Available	Not Available
Water Solubility	Not Available	Not Available
LogP	Not Available	Not Available

Experimental Chromatographic Properties

Experimental Collision Cross Sections

Adduct Type	Data Source	CCS Value (Å²)	Reference
[M-H]-	Not Available	143.473	http://allccs.zhulab.cn/database/detail?ID=AllCCS00000385

Predicted Molecular Properties

Property	Value	Source
Water Solubility	31.4 g/L	ALOGPS
logP	-2.1	ALOGPS
logP	-3.1	ChemAxon
logS	-0.92	ALOGPS
pKa (Strongest Acidic)	1.22	ChemAxon
pKa (Strongest Basic)	-3.6	ChemAxon
Physiological Charge	-2	ChemAxon
Hydrogen Acceptor Count	8	ChemAxon
Hydrogen Donor Count	6	ChemAxon
Polar Surface Area	156.91 Å²	ChemAxon
Rotatable Bond Count	3	ChemAxon
Refractivity	46.8 m³·mol⁻¹	ChemAxon
Polarizability	20.99 Å³	ChemAxon
Number of Rings	1	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	No	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	No	ChemAxon
MDDR-like Rule	No	ChemAxon

Predicted Chromatographic Properties

Predicted Collision Cross Sections

Predictor	Adduct Type	CCS Value (Å²)	Reference
DarkChem	[M+H]+	153.676	31661259
DarkChem	[M-H]-	149.805	31661259
AllCCS	[M+H]+	156.316	32859911
AllCCS	[M-H]-	147.163	32859911
DeepCCS	[M+H]+	143.584	30932474
DeepCCS	[M-H]-	141.189	30932474
DeepCCS	[M-2H]-	175.77	30932474
DeepCCS	[M+Na]+	150.208	30932474
AllCCS	[M+H]+	156.3	32859911
AllCCS	[M+H-H2O]+	152.8	32859911
AllCCS	[M+NH4]+	159.6	32859911
AllCCS	[M+Na]+	160.5	32859911
AllCCS	[M-H]-	147.2	32859911
AllCCS	[M+Na-2H]-	147.5	32859911
AllCCS	[M+HCOO]-	147.9	32859911

Predicted Kovats Retention Indices

Underivatized

Metabolite	SMILES	Kovats RI Value	Column Type	Reference
Mannose 6-phosphate	O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O	3490.8	Standard polar	33892256
Mannose 6-phosphate	O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O	2068.8	Standard non polar	33892256
Mannose 6-phosphate	O[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]1O	2270.1	Semi standard non polar	33892256

Derivatized

Derivative Name / Structure	SMILES	Kovats RI Value	Column Type	Reference
Mannose 6-phosphate,1TMS,isomer #1	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@@H]1O	2119.1	Semi standard non polar	33892256
Mannose 6-phosphate,1TMS,isomer #2	C[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O)O[C@@H](O)[C@@H](O)[C@H]1O	2099.4	Semi standard non polar	33892256
Mannose 6-phosphate,1TMS,isomer #3	C[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O)O)[C@H]1O	2103.7	Semi standard non polar	33892256
Mannose 6-phosphate,1TMS,isomer #4	C[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O)[C@@H](COP(=O)(O)O)O[C@H]1O	2111.9	Semi standard non polar	33892256
Mannose 6-phosphate,1TMS,isomer #5	C[Si](C)(C)OP(=O)(O)OC[C@H]1O[C@@H](O)[C@@H](O)[C@@H](O)[C@@H]1O	2258.3	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #1	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H]1O	2073.3	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #10	C[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O)[C@@H](COP(=O)(O)O[Si](C)(C)C)O[C@H]1O	2221.4	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #11	C[Si](C)(C)OP(=O)(OC[C@H]1O[C@@H](O)[C@@H](O)[C@@H](O)[C@@H]1O)O[Si](C)(C)C	2262.3	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #2	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H]1O	2088.7	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #3	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@@H]1O[Si](C)(C)C	2065.5	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #4	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@H](O)[C@@H]1O	2208.5	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #5	C[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H](COP(=O)(O)O)O[C@H]1O	2082.7	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #6	C[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O)O)[C@H]1O[Si](C)(C)C	2066.5	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #7	C[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O[Si](C)(C)C)O[C@@H](O)[C@@H](O)[C@H]1O	2194.6	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #8	C[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H](COP(=O)(O)O)O[C@H]1O	2080.6	Semi standard non polar	33892256
Mannose 6-phosphate,2TMS,isomer #9	C[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@H]1O	2207.1	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #1	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O	2106.4	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #10	C[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@H]1O[Si](C)(C)C	2140.4	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #11	C[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@@H](O)[C@@H](O)[C@H]1O	2175.7	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #12	C[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H](COP(=O)(O)O[Si](C)(C)C)O[C@H]1O	2178.2	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #13	C[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@H]1O	2169.0	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #14	C[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O)[C@@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@H]1O	2199.4	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #2	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H]1O[Si](C)(C)C	2104.9	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #3	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H]1O	2139.8	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #4	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2110.2	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #5	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H]1O	2165.8	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #6	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@H](O)[C@@H]1O[Si](C)(C)C	2128.6	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #7	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O)[C@@H]1O	2161.1	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #8	C[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H](COP(=O)(O)O)O[C@H]1O	2125.4	Semi standard non polar	33892256
Mannose 6-phosphate,3TMS,isomer #9	C[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H](COP(=O)(O)O[Si](C)(C)C)O[C@H]1O	2193.8	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #1	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2129.8	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #10	C[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@H]1O[Si](C)(C)C	2199.4	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #11	C[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@H]1O	2243.0	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #2	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O	2204.3	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #3	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H]1O[Si](C)(C)C	2201.8	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #4	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H]1O	2193.7	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #5	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2205.6	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #6	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H]1O	2223.7	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #7	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O)[C@@H]1O[Si](C)(C)C	2182.9	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #8	C[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H](COP(=O)(O)O[Si](C)(C)C)O[C@H]1O	2217.3	Semi standard non polar	33892256
Mannose 6-phosphate,4TMS,isomer #9	C[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@H]1O	2260.4	Semi standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #1	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2216.9	Semi standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #1	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2232.2	Standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #1	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2598.4	Standard polar	33892256
Mannose 6-phosphate,5TMS,isomer #2	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O	2241.3	Semi standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #2	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O	2261.9	Standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #2	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O	2478.6	Standard polar	33892256
Mannose 6-phosphate,5TMS,isomer #3	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H]1O[Si](C)(C)C	2236.9	Semi standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #3	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H]1O[Si](C)(C)C	2263.5	Standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #3	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O)[C@@H]1O[Si](C)(C)C	2465.6	Standard polar	33892256
Mannose 6-phosphate,5TMS,isomer #4	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2240.2	Semi standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #4	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2262.3	Standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #4	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2508.1	Standard polar	33892256
Mannose 6-phosphate,5TMS,isomer #5	C[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@H]1O	2255.9	Semi standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #5	C[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@H]1O	2252.6	Standard non polar	33892256
Mannose 6-phosphate,5TMS,isomer #5	C[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)O[C@H]1O	2475.9	Standard polar	33892256
Mannose 6-phosphate,6TMS,isomer #1	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2260.7	Semi standard non polar	33892256
Mannose 6-phosphate,6TMS,isomer #1	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2286.5	Standard non polar	33892256
Mannose 6-phosphate,6TMS,isomer #1	C[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C)O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H]1O[Si](C)(C)C	2423.5	Standard polar	33892256
Mannose 6-phosphate,1TBDMS,isomer #1	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@@H]1O	2369.9	Semi standard non polar	33892256
Mannose 6-phosphate,1TBDMS,isomer #2	CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O)O[C@@H](O)[C@@H](O)[C@H]1O	2381.0	Semi standard non polar	33892256
Mannose 6-phosphate,1TBDMS,isomer #3	CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O)O)[C@H]1O	2384.4	Semi standard non polar	33892256
Mannose 6-phosphate,1TBDMS,isomer #4	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O)[C@@H](COP(=O)(O)O)O[C@H]1O	2398.5	Semi standard non polar	33892256
Mannose 6-phosphate,1TBDMS,isomer #5	CC(C)(C)[Si](C)(C)OP(=O)(O)OC[C@H]1O[C@@H](O)[C@@H](O)[C@@H](O)[C@@H]1O	2514.5	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #1	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H]1O	2510.5	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #10	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O)[C@@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)O[C@H]1O	2688.1	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #11	CC(C)(C)[Si](C)(C)OP(=O)(OC[C@H]1O[C@@H](O)[C@@H](O)[C@@H](O)[C@@H]1O)O[Si](C)(C)C(C)(C)C	2744.4	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #2	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O	2514.9	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #3	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C	2508.1	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #4	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O)[C@@H]1O	2637.7	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #5	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](COP(=O)(O)O)O[C@H]1O	2545.2	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #6	CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O)O)[C@H]1O[Si](C)(C)C(C)(C)C	2523.9	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #7	CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)O[C@@H](O)[C@@H](O)[C@H]1O	2666.7	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #8	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H](COP(=O)(O)O)O[C@H]1O	2531.9	Semi standard non polar	33892256
Mannose 6-phosphate,2TBDMS,isomer #9	CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@H]1O	2662.8	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #1	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O	2738.2	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #10	CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C	2809.1	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #11	CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@@H](O)[C@@H](O)[C@H]1O	2857.4	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #12	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)O[C@H]1O	2821.0	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #13	CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H]1O	2844.6	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #14	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O)[C@@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@H]1O	2872.3	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #2	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C	2734.5	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #3	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H]1O	2788.5	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #4	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C	2749.5	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #5	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O	2784.5	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #6	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C	2782.3	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #7	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O)[C@@H]1O	2827.3	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #8	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](COP(=O)(O)O)O[C@H]1O	2773.8	Semi standard non polar	33892256
Mannose 6-phosphate,3TBDMS,isomer #9	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)O[C@H]1O	2835.6	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #1	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C	2982.8	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #10	CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O)[C@H](O)O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@H]1O[Si](C)(C)C(C)(C)C	3022.7	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #11	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@H]1O	3041.3	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #2	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O	2994.1	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #3	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C	3001.9	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #4	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H]1O	3006.4	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #5	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C	3003.0	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #6	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O	3012.4	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #7	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C	3000.1	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #8	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)O[C@H]1O	3039.4	Semi standard non polar	33892256
Mannose 6-phosphate,4TBDMS,isomer #9	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@H]1O	3064.3	Semi standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #1	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C	3237.9	Semi standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #1	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C	3130.3	Standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #1	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C	3025.3	Standard polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #2	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O	3222.9	Semi standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #2	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O	3123.2	Standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #2	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O	2948.2	Standard polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #3	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C	3231.3	Semi standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #3	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C	3134.3	Standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #3	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O)[C@@H]1O[Si](C)(C)C(C)(C)C	2933.8	Standard polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #4	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C	3229.6	Semi standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #4	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C	3116.4	Standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #4	CC(C)(C)[Si](C)(C)O[C@@H]1O[C@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)[C@@H](O)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C	2968.2	Standard polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #5	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@H]1O	3259.2	Semi standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #5	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@H]1O	3134.6	Standard non polar	33892256
Mannose 6-phosphate,5TBDMS,isomer #5	CC(C)(C)[Si](C)(C)O[C@H]1[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](COP(=O)(O[Si](C)(C)C(C)(C)C)O[Si](C)(C)C(C)(C)C)O[C@H]1O	2945.0	Standard polar	33892256

Spectra

GC-MS Spectra

Spectrum Type	Description	Splash Key	Deposition Date	Source	View
Predicted GC-MS	Predicted GC-MS Spectrum - Mannose 6-phosphate GC-MS (Non-derivatized) - 70eV, Positive	splash10-0005-9740000000-a6e81224fb97751dc2e6	2016-09-22	Wishart Lab	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - Mannose 6-phosphate GC-MS (4 TMS) - 70eV, Positive	splash10-001i-2533590000-b6a62e882bfffed3184a	2017-10-06	Wishart Lab	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - Mannose 6-phosphate GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	Wishart Lab	View Spectrum
Predicted GC-MS	Predicted GC-MS Spectrum - Mannose 6-phosphate GC-MS (Non-derivatized) - 70eV, Positive	Not Available	2021-10-12	Wishart Lab	View Spectrum

MS/MS Spectra

Spectrum Type	Description	Splash Key	Deposition Date	Source	View
Experimental LC-MS/MS	LC-MS/MS Spectrum - Mannose 6-phosphate Quattro_QQQ 10V, Positive-QTOF (Annotated)	splash10-0007-3490000000-734a88a9b3fd55b3e43f	2012-07-24	HMDB team, MONA	View Spectrum
Experimental LC-MS/MS	LC-MS/MS Spectrum - Mannose 6-phosphate Quattro_QQQ 25V, Positive-QTOF (Annotated)	splash10-052b-9300000000-2c63b28f70b6b2eb75a1	2012-07-24	HMDB team, MONA	View Spectrum
Experimental LC-MS/MS	LC-MS/MS Spectrum - Mannose 6-phosphate Quattro_QQQ 40V, Positive-QTOF (Annotated)	splash10-00l2-9000000000-5406aea843f73d03563c	2012-07-24	HMDB team, MONA	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 10V, Positive-QTOF	splash10-03di-0490000000-94ea79ec673f4688b7a0	2016-09-12	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 20V, Positive-QTOF	splash10-03dm-5940000000-c649262446626dcb8d6e	2016-09-12	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 40V, Positive-QTOF	splash10-0uka-9800000000-aae2cb792906d2dec6cd	2016-09-12	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 10V, Negative-QTOF	splash10-0a6r-8290000000-8e20219f94b3fe964e38	2016-09-12	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 20V, Negative-QTOF	splash10-004i-9000000000-b19b64f5cb4124047baf	2016-09-12	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 40V, Negative-QTOF	splash10-004i-9000000000-ecb75a44e3d25affdf31	2016-09-12	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 10V, Negative-QTOF	splash10-0a6s-9060000000-b446300429049a22bea4	2021-09-25	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 20V, Negative-QTOF	splash10-004i-9000000000-d5aaca13a836cb9f1725	2021-09-25	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 40V, Negative-QTOF	splash10-004i-9000000000-a5e502a2627af2048a1f	2021-09-25	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 10V, Positive-QTOF	splash10-03dm-0970000000-40dbaf3d3c72cf65bf47	2021-09-25	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 20V, Positive-QTOF	splash10-01ot-7900000000-00bc03290b6c0bfb7f84	2021-09-25	Wishart Lab	View Spectrum
Predicted LC-MS/MS	Predicted LC-MS/MS Spectrum - Mannose 6-phosphate 40V, Positive-QTOF	splash10-000t-9000000000-7a6ff6606f1dbc2f0ae4	2021-09-25	Wishart Lab	View Spectrum

NMR Spectra

Spectrum Type	Description	Deposition Date	Source	View
Predicted 1D NMR	¹³C NMR Spectrum (1D, 100 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹H NMR Spectrum (1D, 100 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹³C NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹H NMR Spectrum (1D, 1000 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹³C NMR Spectrum (1D, 200 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹H NMR Spectrum (1D, 200 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹³C NMR Spectrum (1D, 300 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹H NMR Spectrum (1D, 300 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹³C NMR Spectrum (1D, 400 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹H NMR Spectrum (1D, 400 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹³C NMR Spectrum (1D, 500 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹³C NMR Spectrum (1D, 600 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹H NMR Spectrum (1D, 600 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹³C NMR Spectrum (1D, 700 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹H NMR Spectrum (1D, 700 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹³C NMR Spectrum (1D, 800 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹H NMR Spectrum (1D, 800 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹³C NMR Spectrum (1D, 900 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Predicted 1D NMR	¹H NMR Spectrum (1D, 900 MHz, H₂O, predicted)	2022-08-20	Wishart Lab	View Spectrum
Experimental 2D NMR	[¹H, ¹³C]-HSQC NMR Spectrum (2D, 600 MHz, H₂O, experimental)	2012-12-05	Wishart Lab	View Spectrum

Biological Properties

Cellular Locations

Cytoplasm (predicted from logP)

Biospecimen Locations

Feces

Tissue Locations

Fibroblasts
Intestine
Liver
Prostate
Spleen
Testis

Pathways

Name	SMPDB/PathBank	KEGG
Fructose and mannose metabolism	Not Available
Fructosuria		Not Available
Fructose intolerance, hereditary		Not Available

Normal Concentrations

Biospecimen	Status	Value	Age	Sex	Condition	Reference	Details
Feces	Detected but not Quantified	Not Quantified	Adult (>18 years old)	Both	Normal	25037050	details

Abnormal Concentrations

Biospecimen	Status	Value	Age	Sex	Condition	Reference	Details
Feces	Detected but not Quantified	Not Quantified	Adult (>18 years old)	Both	Colorectal cancer	25037050	details

Associated Disorders and Diseases

Disease References

Colorectal cancer
Goedert JJ, Sampson JN, Moore SC, Xiao Q, Xiong X, Hayes RB, Ahn J, Shi J, Sinha R: Fecal metabolomics: assay performance and association with colorectal cancer. Carcinogenesis. 2014 Sep;35(9):2089-96. doi: 10.1093/carcin/bgu131. Epub 2014 Jul 18. [PubMed:25037050 ]

Associated OMIM IDs

114500 (Colorectal cancer)

External Links

DrugBank ID

Not Available

Phenol Explorer Compound ID

Not Available

FooDB ID

FDB022411

KNApSAcK ID

Not Available

Chemspider ID

388338

KEGG Compound ID

C00275

BioCyc ID

Not Available

BiGG ID

Wikipedia Link

METLIN ID

PubChem Compound

PDB ID

Not Available

ChEBI ID

49728

Food Biomarker Ontology

Not Available

VMH ID

MAN6P

MarkerDB ID

Not Available

Good Scents ID

Not Available

References

Synthesis Reference

Pascual, C.; Herrera, L. Use of permeabilized yeast cells as a system of enzyme immobilization. Its use for the preparation of mannose 6-phosphate. Folia Microbiologica (Prague, Czech Republic) (1981), 26(2), 103-6.

Material Safety Data Sheet (MSDS)

Download (PDF)

General References

Tiede S, Muschol N, Reutter G, Cantz M, Ullrich K, Braulke T: Missense mutations in N-acetylglucosamine-1-phosphotransferase alpha/beta subunit gene in a patient with mucolipidosis III and a mild clinical phenotype. Am J Med Genet A. 2005 Sep 1;137A(3):235-40. [PubMed:16094673 ]
Sreekumar A, Poisson LM, Rajendiran TM, Khan AP, Cao Q, Yu J, Laxman B, Mehra R, Lonigro RJ, Li Y, Nyati MK, Ahsan A, Kalyana-Sundaram S, Han B, Cao X, Byun J, Omenn GS, Ghosh D, Pennathur S, Alexander DC, Berger A, Shuster JR, Wei JT, Varambally S, Beecher C, Chinnaiyan AM: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature. 2009 Feb 12;457(7231):910-4. doi: 10.1038/nature07762. [PubMed:19212411 ]
DeRossi C, Bode L, Eklund EA, Zhang F, Davis JA, Westphal V, Wang L, Borowsky AD, Freeze HH: Ablation of mouse phosphomannose isomerase (Mpi) causes mannose 6-phosphate accumulation, toxicity, and embryonic lethality. J Biol Chem. 2006 Mar 3;281(9):5916-27. Epub 2005 Dec 8. [PubMed:16339137 ]
Beljaars L, Molema G, Weert B, Bonnema H, Olinga P, Groothuis GM, Meijer DK, Poelstra K: Albumin modified with mannose 6-phosphate: A potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells. Hepatology. 1999 May;29(5):1486-93. [PubMed:10216133 ]
van der Ploeg AT, van der Kraaij AM, Willemsen R, Kroos MA, Loonen MC, Koster JF, Reuser AJ: Rat heart perfusion as model system for enzyme replacement therapy in glycogenosis type II. Pediatr Res. 1990 Oct;28(4):344-7. [PubMed:2235132 ]
Yatziv S, Barfi G, Newburg DS: Lysosomal hydrolases in blood-derived macrophages of patients with I-cell disease. J Lab Clin Med. 1986 Oct;108(4):365-8. [PubMed:3093618 ]
Puolakkainen M, Kuo CC, Campbell LA: Chlamydia pneumoniae uses the mannose 6-phosphate/insulin-like growth factor 2 receptor for infection of endothelial cells. Infect Immun. 2005 Aug;73(8):4620-5. [PubMed:16040974 ]
Holtta-Vuori M, Maatta J, Ullrich O, Kuismanen E, Ikonen E: Mobilization of late-endosomal cholesterol is inhibited by Rab guanine nucleotide dissociation inhibitor. Curr Biol. 2000 Jan 27;10(2):95-8. [PubMed:10662671 ]
Harper J, Burns JL, Foulstone EJ, Pignatelli M, Zaina S, Hassan AB: Soluble IGF2 receptor rescues Apc(Min/+) intestinal adenoma progression induced by Igf2 loss of imprinting. Cancer Res. 2006 Feb 15;66(4):1940-8. [PubMed:16488992 ]
Saris JJ, Derkx FH, De Bruin RJ, Dekkers DH, Lamers JM, Saxena PR, Schalekamp MA, Jan Danser AH: High-affinity prorenin binding to cardiac man-6-P/IGF-II receptors precedes proteolytic activation to renin. Am J Physiol Heart Circ Physiol. 2001 Apr;280(4):H1706-15. [PubMed:11247783 ]
Bird CH, Sun J, Ung K, Karambalis D, Whisstock JC, Trapani JA, Bird PI: Cationic sites on granzyme B contribute to cytotoxicity by promoting its uptake into target cells. Mol Cell Biol. 2005 Sep;25(17):7854-67. [PubMed:16107729 ]
Adrian JE, Poelstra K, Scherphof GL, Molema G, Meijer DK, Reker-Smit C, Morselt HW, Kamps JA: Interaction of targeted liposomes with primary cultured hepatic stellate cells: Involvement of multiple receptor systems. J Hepatol. 2006 Mar;44(3):560-7. Epub 2005 Oct 19. [PubMed:16368158 ]
Ullrich K, Basner R, Gieselmann V, Von Figura K: Recognition of human urine alpha-N-acetylglucosaminidase by rat hepatocytes. Involvement of receptors specific for galactose, mannose 6-phosphate and mannose. Biochem J. 1979 May 15;180(2):413-9. [PubMed:114170 ]
Davis JA, Wu XH, Wang L, DeRossi C, Westphal V, Wu R, Alton G, Srikrishna G, Freeze HH: Molecular cloning, gene organization, and expression of mouse Mpi encoding phosphomannose isomerase. Glycobiology. 2002 Jul;12(7):435-42. [PubMed:12122025 ]
Kaplan A, Fischer D, Achord D, Sly W: Phosphohexosyl recognition is a general characteristic of pinocytosis of lysosomal glycosidases by human fibroblasts. J Clin Invest. 1977 Nov;60(5):1088-93. [PubMed:908752 ]
Lobel P, Dahms NM, Breitmeyer J, Chirgwin JM, Kornfeld S: Cloning of the bovine 215-kDa cation-independent mannose 6-phosphate receptor. Proc Natl Acad Sci U S A. 1987 Apr;84(8):2233-7. [PubMed:2951738 ]
Maguchi S, Taniguchi N, Makita A: Elevated activity and increased mannose-6-phosphate in the carbohydrate moiety of cathepsin D from human hepatoma. Cancer Res. 1988 Jan 15;48(2):362-7. [PubMed:2825973 ]
Sleat DE, Wang Y, Sohar I, Lackland H, Li Y, Li H, Zheng H, Lobel P: Identification and validation of mannose 6-phosphate glycoproteins in human plasma reveal a wide range of lysosomal and non-lysosomal proteins. Mol Cell Proteomics. 2006 Oct;5(10):1942-56. Epub 2006 May 17. [PubMed:16709564 ]
Sleat DE, Sohar I, Lackland H, Majercak J, Lobel P: Rat brain contains high levels of mannose-6-phosphorylated glycoproteins including lysosomal enzymes and palmitoyl-protein thioesterase, an enzyme implicated in infantile neuronal lipofuscinosis. J Biol Chem. 1996 Aug 9;271(32):19191-8. [PubMed:8702598 ]

Only showing the first 10 proteins. There are 16 proteins in total.

Show all enzymes and transporters

Enzymes

Enzyme Details

1. Glucokinase

General function:: Involved in ATP binding
Specific function:: Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the synthesis of glycogen. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.
Gene Name:: GCK
Uniprot ID:: P35557
Molecular weight:: 52191.07

Enzyme Details

2. Hexokinase-3

General function:: Involved in ATP binding
Specific function:: Not Available
Gene Name:: HK3
Uniprot ID:: P52790
Molecular weight:: 99024.56

Reactions

Adenosine triphosphate + D-Mannose → ADP + Mannose 6-phosphate	details

Enzyme Details

3. Hexokinase-2

General function:: Involved in ATP binding
Specific function:: Not Available
Gene Name:: HK2
Uniprot ID:: P52789
Molecular weight:: 102379.06

Reactions

Adenosine triphosphate + D-Mannose → ADP + Mannose 6-phosphate	details

Enzyme Details

4. Hexokinase-1

General function:: Involved in ATP binding
Specific function:: Not Available
Gene Name:: HK1
Uniprot ID:: P19367
Molecular weight:: 102485.1

Reactions

Adenosine triphosphate + D-Mannose → ADP + Mannose 6-phosphate	details

Enzyme Details

5. Mannose-6-phosphate isomerase

General function:: Involved in mannose-6-phosphate isomerase activity
Specific function:: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Gene Name:: MPI
Uniprot ID:: P34949
Molecular weight:: 46655.44

Reactions

Mannose 6-phosphate → Fructose 6-phosphate	details
Mannose 6-phosphate → Beta-D-Fructose 6-phosphate	details

Enzyme Details

6. Phosphomannomutase 2

General function:: Involved in catalytic activity
Specific function:: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions (By similarity).
Gene Name:: PMM2
Uniprot ID:: O15305
Molecular weight:: 28081.925

Reactions

D-Mannose 1-phosphate → Mannose 6-phosphate	details
Mannose 6-phosphate → D-Mannose 1-phosphate	details

Enzyme Details

7. Phosphomannomutase 1

General function:: Involved in metal ion binding
Specific function:: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. In addition, may be responsible for the degradation of glucose-1,6-bisphosphate in ischemic brain.
Gene Name:: PMM1
Uniprot ID:: Q92871
Molecular weight:: 29746.545

Reactions

D-Mannose 1-phosphate → Mannose 6-phosphate	details
Mannose 6-phosphate → D-Mannose 1-phosphate	details

Enzyme Details

8. Perilipin-3

General function:: Involved in protein binding
Specific function:: Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network
Gene Name:: PLIN3
Uniprot ID:: O60664
Molecular weight:: 47046.6

Enzyme Details

9. Cation-dependent mannose-6-phosphate receptor

General function:: Involved in protein binding
Specific function:: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex
Gene Name:: M6PR
Uniprot ID:: P20645
Molecular weight:: 30993.1

Enzyme Details

10. Cation-independent mannose-6-phosphate receptor

General function:: Involved in transporter activity
Specific function:: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4
Gene Name:: IGF2R
Uniprot ID:: P11717
Molecular weight:: 274273.3

Only showing the first 10 proteins. There are 16 proteins in total.

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Showing metabocard for Mannose 6-phosphate (HMDB0001078)

MOL for HMDB0001078 (Mannose 6-phosphate)

3D MOL for HMDB0001078 (Mannose 6-phosphate)

3D SDF for HMDB0001078 (Mannose 6-phosphate)

3D-SDF for HMDB0001078 (Mannose 6-phosphate)

PDB for HMDB0001078 (Mannose 6-phosphate)

3D PDB for HMDB0001078 (Mannose 6-phosphate)

SMILES for HMDB0001078 (Mannose 6-phosphate)

INCHI for HMDB0001078 (Mannose 6-phosphate)

Structure for HMDB0001078 (Mannose 6-phosphate)

3D Structure for HMDB0001078 (Mannose 6-phosphate)

Experimental Collision Cross Sections

Predicted Collision Cross Sections

Predicted Kovats Retention Indices

Underivatized

Derivatized

GC-MS Spectra

MS/MS Spectra

NMR Spectra

Enzymes

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