Hmdb loader
Identification
HMDB Protein ID HMDBP14019
Secondary Accession Numbers None
Name Carnosine N-methyltransferase 2
Synonyms
  1. Histamine N-methyltransferase-like
  2. HNMT-like
Gene Name (REFSEQ) CARNOSINE N-METHYLTRANSFERASE 2
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function N-methyltransferase that mediates the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles.
Pathways
  • Histidine metabolism
Reactions Not Available
GO Classification
Biological Process
carnosine metabolic process
methylation
Molecular Function
N-methyltransferase activity
carnosine N-methyltransferase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 322
Molecular Weight 36375.155
Theoretical pI 6.04
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID U3NEE3
UniProtKB/Swiss-Prot Entry Name HNMTL_CHICK
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Drozak J, Chrobok L, Poleszak O, Jagielski AK, Derlacz R: Molecular identification of carnosine N-methyltransferase as chicken histamine N-methyltransferase-like protein (hnmt-like). PLoS One. 2013 May 21;8(5):e64805. doi: 10.1371/journal.pone.0064805. Print 2013. [PubMed:23705015 ]
  2. Authors unspecified: Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature. 2004 Dec 9;432(7018):695-716. doi: 10.1038/nature03154. [PubMed:15592404 ]