Identification |
HMDB Protein ID
| HMDBP14019 |
Secondary Accession Numbers
| None |
Name
| Carnosine N-methyltransferase 2 |
Synonyms
|
- Histamine N-methyltransferase-like
- HNMT-like
|
Gene Name
| (REFSEQ) CARNOSINE N-METHYLTRANSFERASE 2 |
Protein Type
| Unknown |
Biological Properties |
General Function
| Not Available |
Specific Function
| N-methyltransferase that mediates the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine. Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles. |
Pathways
|
|
Reactions
| Not Available |
GO Classification
|
Biological Process |
carnosine metabolic process |
methylation |
Molecular Function |
N-methyltransferase activity |
carnosine N-methyltransferase activity |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 322 |
Molecular Weight
| 36375.155 |
Theoretical pI
| 6.04 |
Pfam Domain Function
|
Not Available |
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
Not Available
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| U3NEE3 |
UniProtKB/Swiss-Prot Entry Name
| HNMTL_CHICK |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| - Drozak J, Chrobok L, Poleszak O, Jagielski AK, Derlacz R: Molecular identification of carnosine N-methyltransferase as chicken histamine N-methyltransferase-like protein (hnmt-like). PLoS One. 2013 May 21;8(5):e64805. doi: 10.1371/journal.pone.0064805. Print 2013. [PubMed:23705015 ]
- Authors unspecified: Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution. Nature. 2004 Dec 9;432(7018):695-716. doi: 10.1038/nature03154. [PubMed:15592404 ]
|