| Identification |
|---|
| HMDB Protein ID
| HMDBP12582 |
| Secondary Accession Numbers
| None |
| Name
| Ornithine carbamoyltransferase |
| Synonyms
|
- OTCase
|
| Gene Name
| ARGF |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. |
| Pathways
|
- Arginine biosynthesis
- Biosynthesis of amino acids
- Biosynthesis of secondary metabolites
- L-arginine biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| citrulline biosynthetic process |
| arginine biosynthetic process via ornithine |
| Cellular Component |
| cytoplasm |
| Molecular Function |
| ornithine carbamoyltransferase activity |
| amino acid binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 331 |
| Molecular Weight
| 36715.7 |
| Theoretical pI
| 6.247 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P0DH57 |
| UniProtKB/Swiss-Prot Entry Name
| OTC_NEIMB |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Zhou J, Spratt BG: Sequence diversity within the argF, fbp and recA genes of natural isolates of Neisseria meningitidis: interspecies recombination within the argF gene. Mol Microbiol. 1992 Aug;6(15):2135-46. doi: 10.1111/j.1365-2958.1992.tb01387.x. [PubMed:1406254 ]
- Smith NH, Holmes EC, Donovan GM, Carpenter GA, Spratt BG: Networks and groups within the genus Neisseria: analysis of argF, recA, rho, and 16S rRNA sequences from human Neisseria species. Mol Biol Evol. 1999 Jun;16(6):773-83. doi: 10.1093/oxfordjournals.molbev.a026162. [PubMed:10368955 ]
- Tettelin H, Saunders NJ, Heidelberg J, Jeffries AC, Nelson KE, Eisen JA, Ketchum KA, Hood DW, Peden JF, Dodson RJ, Nelson WC, Gwinn ML, DeBoy R, Peterson JD, Hickey EK, Haft DH, Salzberg SL, White O, Fleischmann RD, Dougherty BA, Mason T, Ciecko A, Parksey DS, Blair E, Cittone H, Clark EB, Cotton MD, Utterback TR, Khouri H, Qin H, Vamathevan J, Gill J, Scarlato V, Masignani V, Pizza M, Grandi G, Sun L, Smith HO, Fraser CM, Moxon ER, Rappuoli R, Venter JC: Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science. 2000 Mar 10;287(5459):1809-15. doi: 10.1126/science.287.5459.1809. [PubMed:10710307 ]
|
