Hmdb loader
Identification
HMDB Protein ID HMDBP12482
Secondary Accession Numbers None
Name Dihydroorotase
Synonyms
  1. DHOase
Gene Name PYRC
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
Pathways
  • Biosynthesis of cofactors
  • Pyrimidine metabolism
  • UMP biosynthesis via de novo pathway
Reactions Not Available
GO Classification
Biological Process
pyrimidine nucleobase biosynthetic process
'de novo' UMP biosynthetic process
Molecular Function
zinc ion binding
dihydroorotase activity
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 339
Molecular Weight 37914.66
Theoretical pI 6.916
Pfam Domain Function Not Available
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9ZLQ0
UniProtKB/Swiss-Prot Entry Name PYRC_HELPJ
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Alm RA, Ling LS, Moir DT, King BL, Brown ED, Doig PC, Smith DR, Noonan B, Guild BC, deJonge BL, Carmel G, Tummino PJ, Caruso A, Uria-Nickelsen M, Mills DM, Ives C, Gibson R, Merberg D, Mills SD, Jiang Q, Taylor DE, Vovis GF, Trust TJ: Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori. Nature. 1999 Jan 14;397(6715):176-80. doi: 10.1038/16495. [PubMed:9923682 ]