| Identification |
|---|
| HMDB Protein ID
| HMDBP11900 |
| Secondary Accession Numbers
| None |
| Name
| DNA primase large subunit |
| Synonyms
|
- DNA primase 58 kDa subunit
- p58
|
| Gene Name
| PRIM2 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
|
| Pathways
|
- DNA replication
- Purine metabolism
- Pyrimidine metabolism
|
| Reactions
|
| Deoxyadenosine triphosphate + DNA → Pyrophosphate + DNA |
details
|
| dGTP + DNA → Pyrophosphate + DNA |
details
|
| dCTP + DNA → Pyrophosphate + DNA |
details
|
| Thymidine 5'-triphosphate + DNA → Pyrophosphate + DNA |
details
|
|
| GO Classification
|
| Biological Process |
| telomere maintenance via recombination |
| telomere maintenance via semi-conservative replication |
| S phase of mitotic cell cycle |
| G1/S transition of mitotic cell cycle |
| DNA strand elongation involved in DNA replication |
| DNA replication initiation |
| M/G1 transition of mitotic cell cycle |
| Cellular Component |
| replisome |
| nucleoplasm |
| Molecular Function |
| metal ion binding |
| DNA primase activity |
| 4 iron, 4 sulfur cluster binding |
| DNA binding |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P49643 |
| UniProtKB/Swiss-Prot Entry Name
| Not Available |
| PDB IDs
|
|
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:9370 |
| References |
|---|
| General References
| Not Available |
