| Identification |
|---|
| HMDB Protein ID
| HMDBP11852 |
| Secondary Accession Numbers
| None |
| Name
| Nucleoside diphosphate kinase homolog 5 |
| Synonyms
|
- NDK-H 5
- NDP kinase homolog 5
- Inhibitor of p53-induced apoptosis-beta
- Testis-specific nm23 homolog
- nm23-H5
- IPIA-beta
|
| Gene Name
| NME5 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity).
|
| Pathways
|
- Purine metabolism
- Pyrimidine metabolism
|
| Reactions
|
| Adenosine triphosphate + ADP → ADP + Adenosine triphosphate |
details
|
| Adenosine triphosphate + Uridine 5'-diphosphate → ADP + Uridine triphosphate |
details
|
| Adenosine triphosphate + Guanosine diphosphate → ADP + Guanosine triphosphate |
details
|
| Adenosine triphosphate + CDP → ADP + Cytidine triphosphate |
details
|
| Adenosine triphosphate + IDP → ADP + Inosine triphosphate |
details
|
| Adenosine triphosphate + dADP → ADP + Deoxyadenosine triphosphate |
details
|
| Adenosine triphosphate + dGDP → ADP + dGTP |
details
|
| Adenosine triphosphate + dTDP → ADP + Thymidine 5'-triphosphate |
details
|
| Adenosine triphosphate + dCDP → ADP + dCTP |
details
|
| Adenosine triphosphate + dUDP → ADP + Deoxyuridine triphosphate |
details
|
| Adenosine triphosphate + dIDP → ADP + 2'-Deoxyinosine triphosphate |
details
|
|
| GO Classification
|
| Biological Process |
| multicellular organismal development |
| negative regulation of apoptotic process |
| spermatid development |
| CTP biosynthetic process |
| GTP biosynthetic process |
| UTP biosynthetic process |
| nucleoside metabolic process |
| Molecular Function |
| ATP binding |
| nucleoside diphosphate kinase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P56597 |
| UniProtKB/Swiss-Prot Entry Name
| Not Available |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:7853 |
| References |
|---|
| General References
| Not Available |
