Showing Protein DNA replication licensing factor MCM4 (HMDBP11818)
| Identification | ||||||||||||||||
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| HMDB Protein ID | HMDBP11818 | |||||||||||||||
| Secondary Accession Numbers | None | |||||||||||||||
| Name | DNA replication licensing factor MCM4 | |||||||||||||||
| Synonyms |
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| Gene Name | MCM4 | |||||||||||||||
| Protein Type | Unknown | |||||||||||||||
| Biological Properties | ||||||||||||||||
| General Function | Not Available | |||||||||||||||
| Specific Function | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. | |||||||||||||||
| Pathways |
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| Reactions |
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| GO Classification |
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| Cellular Location | Not Available | |||||||||||||||
| Gene Properties | ||||||||||||||||
| Chromosome Location | 8 | |||||||||||||||
| Locus | 8q11.2 | |||||||||||||||
| SNPs | Not Available | |||||||||||||||
| Gene Sequence | Not Available | |||||||||||||||
| Protein Properties | ||||||||||||||||
| Number of Residues | Not Available | |||||||||||||||
| Molecular Weight | 96556.97 | |||||||||||||||
| Theoretical pI | 6.735 | |||||||||||||||
| Pfam Domain Function | Not Available | |||||||||||||||
| Signals | Not Available | |||||||||||||||
| Transmembrane Regions | Not Available | |||||||||||||||
| Protein Sequence |
>>gi|33469919|ref|NP_005905.2| DNA replication licensing factor MCM4 [Homo sapiens] MSSPASTPSRRGSRRGRATPAQTPRSEDARSSPSQRRRGEDSTSTGELQPMPTSPGVDLQ SPAAQDVLFS |
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| GenBank ID Protein | Not Available | |||||||||||||||
| UniProtKB/Swiss-Prot ID | P33991 | |||||||||||||||
| UniProtKB/Swiss-Prot Entry Name | Not Available | |||||||||||||||
| PDB IDs | Not Available | |||||||||||||||
| GenBank Gene ID | Not Available | |||||||||||||||
| GeneCard ID | Not Available | |||||||||||||||
| GenAtlas ID | Not Available | |||||||||||||||
| HGNC ID | HGNC:6947 | |||||||||||||||
| References | ||||||||||||||||
| General References | Not Available | |||||||||||||||