| Identification |
|---|
| HMDB Protein ID
| HMDBP11635 |
| Secondary Accession Numbers
| None |
| Name
| Chitinase-3-like protein 1 |
| Synonyms
|
- 39 kDa synovial protein
- Cartilage glycoprotein 39
- YKL-40
- CGP-39
- GP-39
- hCGP-39
|
| Gene Name
| CHI3L1 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Carbohydrate-binding lectin with a preference for chitin. May play a role in defense against pathogens, or in tissue remodeling. May play an important role in the capacity of cells to respond to and cope with changes in their environment.
|
| Pathways
|
- Amino sugar and nucleotide sugar metabolism
|
| Reactions
|
| Chitin + Water → N-Acetyl-D-glucosamine + Chitin |
details
|
| Chitin + Water → N-Acetyl-D-glucosaminide + Chitin |
details
|
|
| GO Classification
|
| Biological Process |
| response to interleukin-1 |
| response to interleukin-6 |
| response to mechanical stimulus |
| inflammatory response |
| cellular response to tumor necrosis factor |
| activation of NF-kappaB-inducing kinase activity |
| cellular response to interleukin-1 |
| chitin catabolic process |
| interleukin-8 secretion |
| positive regulation of angiogenesis |
| positive regulation of ERK1 and ERK2 cascade |
| positive regulation of peptidyl-threonine phosphorylation |
| positive regulation of protein kinase B signaling cascade |
| cartilage development |
| lung development |
| carbohydrate metabolic process |
| Cellular Component |
| endoplasmic reticulum |
| proteinaceous extracellular matrix |
| extracellular space |
| Molecular Function |
| cation binding |
| chitin binding |
| extracellular matrix structural constituent |
| hydrolase activity, hydrolyzing O-glycosyl compounds |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| Not Available |
| Molecular Weight
| Not Available |
| Theoretical pI
| Not Available |
| Pfam Domain Function
|
Not Available |
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P36222 |
| UniProtKB/Swiss-Prot Entry Name
| Not Available |
| PDB IDs
|
|
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:1932 |
| References |
|---|
| General References
| Not Available |
