Human Metabolome Database: Showing Protein Guanine nucleotide exchange factor for Rab-3A (HMDBP11494)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 metabolites

Identification
HMDB Protein ID	HMDBP11494
Secondary Accession Numbers	17846
Name	Guanine nucleotide exchange factor for Rab-3A
Synonyms	Rab-3A-interacting-like protein 1 Rab3A-interacting-like protein 1 Rabin3-like 1
Gene Name	RAB3IL1
Protein Type	Unknown
Biological Properties
General Function	Involved in guanyl-nucleotide exchange factor activity
Specific Function	Guanine nucleotide exchange factor (GEF) for Rab3A, a GTPase that regulates synaptic vesicle exocytosis
Pathways	Not Available
Reactions	Not Available
GO Classification	Not Available
Cellular Location	Not Available
Gene Properties
Chromosome Location	Chromosome:1
Locus	11q12.2
SNPs	RAB3IL1
Gene Sequence	>1149 bp ATGTGGAGCGGCCCACCCCAGCCAGACCAGGGCCTCCCGCCGCCCCTTGCAGCTGTCCCG GTCCCCTGGAAGAGCACGGACCCCTGCCAAGGCCACAGGGAGTCCCCAGGAGCCCTGGTG GAGACCTCTGCAGGGGAGGAGGCCCAAGGCCAGGAGGGCCCCGCAGCCGCCCAGCTGGAC GTGTTGCGCCTGCGCAGCTCTTCCATGGAGATCCGAGAGAAGGGCTCCGAGTTCCTGAAG GAGGAGCTGCACAGAGCGCAGAAGGAGCTGAAGCTAAAGGACGAGGAATGTGAGCGGCTG TCCAAGGTGCGGGAGCAGCTAGAACAGGAGCTGGAAGAGCTGACGGCCAGCCTGTTTGAG GAAGCTCACAAGATGGTTCGAGAAGCCAACATGAAGCAGGCGGCATCAGAAAAGCAGCTG AAGGAGGCTCGGGGCAAGATCGACATGCTGCAGGCAGAGGTGACAGCCTTGAAGACACTG GTCATCACGTCCACACCAGCCTCTCCCAACCGCGAGCTTCACCCCCAGCTGCTGAGCCCC ACCAAGGCCGGGCCCCGAAAGGGCCACTCTCGCCACAAGAGCACCAGCAGCACCCTCTGC CCCGCCGTGTGTCCCGCTGCGGGACACACCCTCACCCCAGACAGAGAGGGCAAGGAGGTG GACACAATCCTGTTTGCAGAGTTCCAGGCCTGGAGGGAATCCCCCACCCTGGACAAGACC TGCCCCTTCCTGGAAAGGGTGTACCGAGAGGACGTGGGCCCCTGCCTGGACTTCACAATG CAGGAGCTCTCGGTGCTGGTACGGGCCGCCGTGGAGGACAACACGCTCACCATTGAGCCG GTGGCTTCGCAGACGCTGCCCACAGTGAAGGTGGCCGAGGTTGACTGTAGCAGCACCAAC ACATGTGCCCTGAGCGGGCTGACCCGCACCTGCCGCCACCGAATCCGGCTCGGGGACTCC AAAAGCCATTACTACATCTCGCCATCTTCCCGGGCCAGGATCACCGCAGTGTGCAACTTC TTCACCTACATCCGCTACATCCAGCAAGGCCTGGTGCGGCAGGACGCAGAGCCCATGTTC TGGGAGATCATGAGGTTGCGGAAGGAGATGTCACTGGCCAAGCTCGGCTTCTTCCCCCAG GAGGCTTAG
Protein Properties
Number of Residues	382
Molecular Weight	42636.2
Theoretical pI	6.43
Pfam Domain Function	Sec2p (PF06428 )
Signals	None
Transmembrane Regions	None
Protein Sequence	>Guanine nucleotide exchange factor for Rab-3A MWSGPPQPDQGLPPPLAAVPVPWKSTDPCQGHRESPGALVETSAGEEAQGQEGPAAAQLD VLRLRSSSMEIREKGSEFLKEELHRAQKELKLKDEECERLSKVREQLEQELEELTASLFE EAHKMVREANMKQAASEKQLKEARGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSP TKAGPRKGHSRHKSTSSTLCPAVCPAAGHTLTPDREGKEVDTILFAEFQAWRESPTLDKT CPFLERVYREDVGPCLDFTMQELSVLVRAAVEDNTLTIEPVASQTLPTVKVAEVDCSSTN TCALSGLTRTCRHRIRLGDSKSHYYISPSSRARITAVCNFFTYIRYIQQGLVRQDAEPMF WEIMRLRKEMSLAKLGFFPQEA
External Links
GenBank ID Protein	21361440
UniProtKB/Swiss-Prot ID	Q8TBN0
UniProtKB/Swiss-Prot Entry Name	R3GEF_HUMAN
PDB IDs	Not Available
GenBank Gene ID	NM_013401.2
GeneCard ID	RAB3IL1
GenAtlas ID	RAB3IL1
HGNC ID	HGNC:9780
References
General References	Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]