Hmdb loader
Identification
HMDB Protein ID HMDBP10988
Secondary Accession Numbers
  • 17306
Name Annexin A9
Synonyms
  1. Annexin XXXI
  2. Annexin-31
  3. Annexin-9
  4. Pemphaxin
Gene Name ANXA9
Protein Type Unknown
Biological Properties
General Function Involved in calcium ion binding
Specific Function Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes
Pathways Not Available
Reactions Not Available
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
calcium-dependent phospholipid binding
calcium ion binding
lipid binding
phospholipid binding
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:1
Locus 1q21
SNPs ANXA9
Gene Sequence
>1038 bp
ATGTCTGTGACTGGCGGGAAGATGGCACCGTCCCTCACCCAGGAGATCCTCAGCCACCTG
GGCCTGGCCAGCAAGACTGCAGCGTGGGGGACCCTGGGCACCCTCAGGACCTTCTTGAAC
TTCAGCGTGGACAAGGATGCGCAGAGGCTACTGAGGGCCATTACTGGCCAAGGCGTGGAC
CGCAGTGCCATTGTGGACGTGCTGACCAACCGGAGCAGAGAGCAAAGGCAGCTCATCTCA
CGAAACTTCCAGGAGCGCACCCAACAGGACCTGATGAAGTCTCTACAGGCAGCACTTTCC
GGCAACCTGGAGAGGATTGTGATGGCTCTGCTGCAGCCCACAGCCCAGTTTGACGCCCAG
GAATTGAGGACAGCTCTGAAGGCCTCAGATTCTGCTGTGGACGTGGCCATTGAAATTCTT
GCCACTCGAACCCCACCCCAGCTGCAGGAGTGCTTGGCAGTCTACAAACACAATTTCCAG
GTGGAGGCTGTGGATGGCATCACATCTGAGACCAGTGGCATCTTGCAGGACCTGCTGTTG
GCCCTGGCCAAGGGGGGCCGTGACAGCTACTCTGGAATCATTGACTATAATCTGGCAGAA
CAAGATGTCCAGGCACTGCAGCGGGCAGAAGGACCTAGCAGAGAGGAAACATGGGTCCCA
GTCTTCACCCAGCGAAATCCTGAACACCTCATCCGAGTGTTTGATCAGTACCAGCGGAGC
ACTGGGCAAGAGCTGGAGGAGGCTGTCCAGAACCGTTTCCATGGAGATGCTCAGGTGGCT
CTGCTCGGCCTAGCTTCGGTGATCAAGAACACACCGCTGTACTTTGCTGACAAACTTCAT
CAAGCCCTCCAGGAAACTGAGCCCAATTACCAAGTCCTGATTCGCATCCTTATCTCTCGA
TGTGAGACTGACCTTCTGAGTATCAGAGCTGAGTTCAGGAAGAAATTTGGGAAGTCCCTC
TACTCTTCTCTCCAGGATGCAGTGAAAGGGGATTGCCAGTCAGCCCTCCTGGCCTTGTGC
AGGGCTGAAGACATGTGA
Protein Properties
Number of Residues 345
Molecular Weight 38363.2
Theoretical pI 5.48
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>Annexin A9
MSVTGGKMAPSLTQEILSHLGLASKTAAWGTLGTLRTFLNFSVDKDAQRLLRAITGQGVD
RSAIVDVLTNRSREQRQLISRNFQERTQQDLMKSLQAALSGNLERIVMALLQPTAQFDAQ
ELRTALKASDSAVDVAIEILATRTPPQLQECLAVYKHNFQVEAVDDITSETSGILQDLLL
ALAKGGRDSYSGIIDYNLAEQDVQALQRAEGPSREETWVPVFTQRNPEHLIRVFDQYQRS
TGQELEEAVQNRFHGDAQVALLGLASVIKNTPLYFADKLHQALQETEPNYQVLIRILISR
CETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCQSALLALCRAEDM
GenBank ID Protein 10436074
UniProtKB/Swiss-Prot ID O76027
UniProtKB/Swiss-Prot Entry Name ANXA9_HUMAN
PDB IDs Not Available
GenBank Gene ID AF230929
GeneCard ID ANXA9
GenAtlas ID ANXA9
HGNC ID HGNC:547
References
General References
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  3. Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villen J, Li J, Cohn MA, Cantley LC, Gygi SP: Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12130-5. Epub 2004 Aug 9. [PubMed:15302935 ]
  4. Morgan RO, Fernandez MP: Expression profile and structural divergence of novel human annexin 31. FEBS Lett. 1998 Sep 4;434(3):300-4. [PubMed:9742942 ]
  5. Nguyen VT, Ndoye A, Grando SA: Pemphigus vulgaris antibody identifies pemphaxin. A novel keratinocyte annexin-like molecule binding acetylcholine. J Biol Chem. 2000 Sep 22;275(38):29466-76. [PubMed:10899159 ]