| Identification |
|---|
| HMDB Protein ID
| HMDBP09180 |
| Secondary Accession Numbers
| |
| Name
| Ferrochelatase |
| Synonyms
|
Not Available
|
| Gene Name
| DKFZp686P18130 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ferrochelatase activity |
| Specific Function
| Catalyzes the ferrous insertion into protoporphyrin IX |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
| Function |
| catalytic activity |
| lyase activity |
| ferrochelatase activity |
| Process |
| metabolic process |
| nitrogen compound metabolic process |
| tetrapyrrole metabolic process |
| porphyrin metabolic process |
| heme biosynthetic process |
| porphyrin biosynthetic process |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| DKFZp686P18130 |
| Gene Sequence
|
>1251 bp
ATGGCTGCGGCCCTGCGCGCCGCGGGCGTCCTGCTCCGCGATCCGCTGGCATCCAGCAGC
TGGAGGGTCTGTCAGCCATGGAGGTGGAAGTCAGGTGCAGCTGCAGCGGCCGTCACCACA
GAAACAGCCCAGCATGCCCAGGGTGCAAAACCTCAAGTTCAACCGCAGAAGAGGAAGCCG
AAAACTGGAATATTAATGCTAAACATGGGAGGCCCTGAAACTCTTGGAGATGTTCACGAC
TTCCTTCTGAGACTCTTCTTGGACCGAGACCTCATGACACTTCCTATTCAGAATAAGCTG
GCACCATTCATCGCCAAACGCCGAACCCCCAAGATTCAAGAGCAGTACCGCAGGATTGGA
GGCGGATCCCCCATCAAGATATGGACTTCCAAGCAGGGAGAGGGCATGGTAAAGCTGCTG
GATGAATTGTCCCCCAACACAGCCCCTCACAAATACTATATTGGATTTCGGTACGTCCAT
CCTTTAACAGAAGAAGCAATTGAAGAGATGGAGAGAGATGGCCTAGAAAGGGCTATTGCT
TTCACACAGTATCCACAGTACAGCTGCTCCACCACAGGCAGCAGCTTAAATGCCATTTAC
AGATACTATAATCAAGTGGGACGGAAGCCCACGATGAAGTGGAGCACTATTGACAGGTGG
CCCACACATCACCTCCTCATCCAGTGCTTTGCAGATCATATTCTAAAGGAACTGGACCAT
TTTCCACTTGAGAAGAGAAGCGAGGTGGTCATTCTGTTTTCTGCTCACTCACTGCCGATG
TCTGTGGTCAACAGAGGCGACCCATATCCTCAGGAGGTAAGCGCCACTGTCCAAAAAGTC
ATGGAAAGGCTGGAGTACTGCAACCCCTACCGACTGGTGTGGCAATCCAAGGTTGGTCCG
ATGCCCTGGTTGGGTCCTCAAACAGACGAATCTATCAAAGGGCTTTGTGAGAGGGGGAGG
AAGAATATCCTCTTGGTTCCGATAGCATTTACCAGTGACCATATTGAAACGCTGTATGAG
CTGGACATCGAGTACTCTCAAGTTTTAGCCAAGGAGTGTGGAGTTGAAAACATCAGAAGA
GCTGAGTCTCTTAATGGAAATCCATTGTTCTCTAAGGCCCTGGCCGACTTGGTGCATTCA
CACATCCAGTCAAACGAGCTGTGTTCCAAGCAGCTGACCCTGAGCTGTCCGCTCTGTGTC
AATCCTGTCTGCAGGGAGACTAAATCCTTCTTCACCAGCCAGCAGCTGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 416 |
| Molecular Weight
| 47131.9 |
| Theoretical pI
| 8.78 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ferrochelatase
MAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQKRKP
KTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPKIQEQYRRIG
GGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLERAIA
FTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILKELDH
FPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQSKVGP
MPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVENIRR
AESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL
|
| External Links |
|---|
| GenBank ID Protein
| 33096717 |
| UniProtKB/Swiss-Prot ID
| Q7KZA3 |
| UniProtKB/Swiss-Prot Entry Name
| Q7KZA3_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| BX571744 |
| GeneCard ID
| DKFZp686P18130 |
| GenAtlas ID
| DKFZp686P18130 |
| HGNC ID
| HGNC:3647 |
| References |
|---|
| General References
| Not Available |
