Identification |
HMDB Protein ID
| HMDBP09143 |
Secondary Accession Numbers
| |
Name
| Arylamine N-acetyltransferase 2 |
Synonyms
|
Not Available
|
Gene Name
| NAT2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in acetyltransferase activity |
Specific Function
| Not Available |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Function |
catalytic activity |
transferase activity |
transferase activity, transferring acyl groups |
transferase activity, transferring acyl groups other than amino-acyl groups |
acyltransferase activity |
acetyltransferase activity |
Process |
metabolic process |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:8 |
Locus
| 8p22 |
SNPs
| NAT2 |
Gene Sequence
|
>873 bp
ATGGACATTGAAGCATATTTTGAAAGAATTGGCTATAAGAACTCTAGGAACAAATTGGAC
TTGGAAACATTAACTGACATTCTTGAGCACCAGATCCGGGCTGTTCCCTTTGAGAACCTT
AACATGCATTGTGGGCAAGCCATGGAGTTGGGCTTAGAGGCTATTTTTGATCACATTGTA
AGAAGAAACCAGGGTGGGTGGTGTCTCCAGGTCAATCAACTTCTGTACTGGGCTCTGACC
ACAATCGGTTTTCAGACCACAATGTTAGGAGGGTATTTTTACATCCCTCCAGTTAACAAA
TACAGCACTGGCATGGTTCACCTTCTCCTGCAGGTGACCATTGACGGCAGGAATTACATT
GTCGATGCTGGGTCTGGAAGCTCCTCCCAGATGTGGCAGCCTCTAGAATTAATTTCTGGG
AAGGATCAGCCTCAGGTGCCTTGCATTTTCTGCTTGACAGAAGAGAGAGGAATCTGGTAC
CTGGACCAAATCAGGAGAGAGCAGTATATTACAAACAAAGAATTTCTTAATTCTCATCTC
CTGCCAAAGAAGAAACACCAAAAAATATACTTATTTACGCTTGAACCTCGAACAATTGAA
GATTTTGAGTCTATGAATACATACCTGCAGACGTCTCCAACATCTTCATTTATAACCACA
TCATTTTGTTCCTTGCAGACCCCAGAAGGGGTTTACTGTTTGGTGGGCTTCATCCTCACC
TATAGAAAATTCAATTATAAAGACAATACAGATCTGGTCGAGTTTAAAACTCTCACTGAG
GAAGAGGTTGAAGAAGTGCTGAAAAATATATTTAAGATTTCCTTGGGGAGAAATCTCGTG
CCCAAACCTGGTGATGGATCCCTTACTATTTAG
|
Protein Properties |
Number of Residues
| 290 |
Molecular Weight
| 33514.2 |
Theoretical pI
| 5.4 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Arylamine N-acetyltransferase 2
MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIV
RRNQGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYI
VDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHL
LPKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILT
YRKFNYKDNTDLVEFKTLTEEEVEEVLKNIFKISLGRNLVPKPGDGSLTI
|
External Links |
GenBank ID Protein
| 93212147 |
UniProtKB/Swiss-Prot ID
| A4Z7P9 |
UniProtKB/Swiss-Prot Entry Name
| A4Z7P9_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| DQ473050 |
GeneCard ID
| NAT2 |
GenAtlas ID
| NAT2 |
HGNC ID
| HGNC:7646 |
References |
General References
| - Sabbagh A, Langaney A, Darlu P, Gerard N, Krishnamoorthy R, Poloni ES: Worldwide distribution of NAT2 diversity: implications for NAT2 evolutionary history. BMC Genet. 2008 Feb 27;9:21. doi: 10.1186/1471-2156-9-21. [PubMed:18304320 ]
|