Showing Protein Cytochrome c oxidase assembly protein COX15 homolog (HMDBP08634)

• 14350

• Acute Intermittent Porphyria
• Congenital Erythropoietic Porphyria (CEP) or Gunther Disease
• heme A biosynthesis
• Hereditary Coproporphyria (HCP)
• Oxidative phosphorylation
• Porphyria Variegata (PV)
• Porphyrin and chlorophyll metabolism
• Porphyrin Metabolism

1. Mitochondrion membrane
2. Multi-pass membrane protein

>1233 bp
ATGCAGCGATTGCTCTTTCCGCCGTTGAGGGCCTTGAAGGGGAGGCAGTATCTGCCGCTC
CTGGCTCCTAGGGCAGCGCCTAAAGCACAGTGTGATTGCATCAGGCGCCCTTTGAGGCCA
GGGCAATACAGCACCATCTCTGAAGTAGCTTTGCAATCTGGAAGGGGTACAGTGTCCCTT
CCCTCAAAGGCTGCTGAGCGGGTGGTGGGCCGATGGCTCCTGGTCTGCAGTGGAACAGTG
GCTGGAGCAGTTATTCTTGGTGGAGTAACTAGGTTGACAGAGTCTGGCCTCTCGATGGTA
GATTGGCATTTAATAAAGGAGATGAAGCCACCTACAAGCCAAGAGGAATGGGAAGCAGAA
TTCCAAAGATACCAGCAATTTCCAGAATTTAAAATCTTGAATCATGATATGACACTGACA
GAATTCAAGTTCATCTGGTACATGGAGTACTCACACCGAATGTGGGGTCGCCTTGTAGGC
CTTGTGTACATCCTGCCTGCTGCCTACTTTTGGAGAAAGGGCTGGCTCAGCCGTGGCATG
AAAGGACGTGTTCTTGCCCTCTGTGGCCTCGTCTGCTTCCAGGGTCTGTTGGGATGGTAT
ATGGTGAAAAGTGGACTAGAAGAAAAATCAGACTCCCATGACATCCCTCGGGTCAGTCAG
TACCGCCTTGCTGCCCACCTGGGATCAGCCCTGGTTCTTTATTGTGCCAGCTTGTGGACC
TCACTGTCACTGCTACTCCCTCCGCACAAGTTGCCTGAAACCCACCAACTCCTACAGTTG
AGACGATTTGCTCATGGAACAGCAGGTCTGGTGTTCCTTACGGCCCTCTCAGGGGCTTTT
GTGGCAGGGCTAGATGCTGGGCTTGTTTATAACTCCTTTCCCAAAATGGGAGAATCCTGG
ATCCCGGAGGACCTCTTTACCTTCTCCCCCATCCTGAGGAATGTTTTTGAGAATCCCACC
ATGGTGCAGTTTGATCACCGGATTCTGGGAATCACTTCAGTCACTGCCATTACAGTGCTC
TACTTCCTCTCTCGGAGAATTCCCCTTCCTAGAAGGACCAAGATGGCAGCAGTGACTCTG
CTGGCTTTGGCGTATACACAGGTGGGCTTGGGCATCAGCACGCTGCTGATGTATGTCCCA
ACTCCTCTGGCCGCCACTCACCAGTCAGGCTCCTTGGCTTTGCTCACTGGTGCTCTTTGG
CTGATGAATGAACTCCGAAGAGTCCCAAAATGA

• COX15-CtaA (PF02628 )

>Cytochrome c oxidase assembly protein COX15 homolog
MQRLLFPPLRALKGRQYLPLLAPRAAPRAQCDCIRRPLRPGQYSTISEVALQSGRGTVSL
PSKAAERVVGRWLLVCSGTVAGAVILGGVTRLTESGLSMVDWHLIKEMKPPTSQEEWEAE
FQRYQQFPEFKILNHDMTLTEFKFIWYMEYSHRMWGRLVGLVYILPAAYFWRKGWLSRGM
KGRVLALCGLVCFQGLLGWYMVKSGLEEKSDSHDIPRVSQYRLAAHLGSALVLYCASLWT
SLSLLLPPHKLPETHQLLQLRRFAHGTAGLVFLTALSGAFVAGLDAGLVYNSFPKMGESW
IPEDLFTFSPILRNVFENPTMVQFDHRILGITSVTAITVLYFLSRRIPLPRRTKMAAVTL
LALAYTQVGLGISTLLMYVPTPLAATHQSGSLALLTGALWLMNELRRVPK

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5. Petruzzella V, Tiranti V, Fernandez P, Ianna P, Carrozzo R, Zeviani M: Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain. Genomics. 1998 Dec 15;54(3):494-504. [PubMed:9878253 ]
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