Hmdb loader
Identification
HMDB Protein ID HMDBP08326
Secondary Accession Numbers
  • 14038
Name Cell cycle progression protein 1
Synonyms
  1. Cell cycle progression restoration protein 8
Gene Name CCPG1
Protein Type Unknown
Biological Properties
General Function Replication, recombination and repair
Specific Function Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42. May be involved in cell cycle regulation
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location
  1. Single-pass type II membrane protein
  2. Cytoplasmic granule membrane
Gene Properties
Chromosome Location Chromosome:1
Locus 15q21.1
SNPs CCPG1
Gene Sequence
>2274 bp
ATGTCTGAAAATTCCAGTGACAGTGATTCATCTTGTGGTTGGACTGTCATCAGTCATGAG
GGGTCAGATATAGAAATGTTGAATTCTGTGACCCCCACTGACAGCTGTGAGCCCGCCCCA
GAATGTTCATCTTTAGAGCAAGAGGAGCTTCAAGCATTGCAGATAGAGCAAGGAGAAAGC
AGCCAAAATGGCACAGTGCTTATGGAAGAAACTGCTTATCCAGCTTTGGAGGAAACCAGC
TCAACAATTGAGGCAGAGGAACAAAAGATACCCGAAGACAGTATCTATATTGGAACTGCC
AGTGATGATTCTGATATTGTTACCCTTGAGCCACCTAAGTTAGAAGAAATTGGAAATCAA
GAAGTTGTCATTGTTGAAGAAGCACAGAGTTCAGAAGACTTTAACATGGGCTCTTCCTCT
AGCAGCCAGTATACTTTCTGTCAGCCAGAAACTGTATTTTCATCTCAGCCTAGTGACGAT
GAATCAAGTAGTGATGAAACCAGTAATCAGCCCAGTCCTGCCTTTAGACGACGCCGTGCT
AGGAAGAAGACCGTTTCTGCTTCAGAATCTGAAGACCGGCTAGTTGCTGAACAAGAAACT
GAACCTTCTAAGGAGTTGAGTAAACGTCAGTTCAGTAGTGGTCTCAATAAGTGTGTTATA
CTTGCTTTGGTGATTGCAATCAGCATGGGATTTGGCCATTTCTATGGCACAATTCAGATT
CAGAAGCGTCAACAGTTAGTCAGAAAGATACATGAAGATGAATTGAATGATATGAAGGAT
TATCTTTCCCAGTGTCAACAGGAACAAGAATCTTTTATAGATTATAAGTCATTGAAAGAA
AATCTTGCAAGGTGTTGGACACTTACTGAAGCAGAGAAGATGTCCTTTGAAACTCAGAAA
ACGAACCTTGCTACAGAAAATCAGTATTTAAGAGTATCCTTGGAGAAGGAAGAAAAAGCC
TTATCCTCATTACAGGAAGAGTTAAACAAACTAAGAGAACAGATTAGAATATTGGAAGAT
AAAGGGACAAGTACTGAATTAGTTAAAGAAAATCAGAAACTTAAGCAGCATTTGGAAGAG
GAAAAGCAGAAAAAACACAGCTTTCTTAGTCAAAGGGAGACTCTGTTGACAGAAGCAAAG
ATGCTAAAGAGAGAACTGGAGAGAGAACGACTAGTAACTACGGCTTTAAGGGGGGAACTC
CAGCAGTTAAGTGGTAGTCAGTTACATGGCAAGTCAGATTCTCCCAATGTATATACTGAA
AAAAAGGAAATAGCAATCTTACGGGAAAGACTCACTGAGCTGGAACGGAAGCTAACCTTC
GAACAGCAGCGTTCTGATTTGTGGGAAAGATTGTATGTTGAGGCAAAAGATCAAAATGGA
AAACAAGGAACAGATGGAAAAAAGAAAGGGGGCAGAGGAAGCCACAGGGCTAAAAATAAG
TCAAAGGAAACATTTTTGGGTTCAGTTAAGGAAACATTTGATGCCATGAAGAATTCTACC
AAGGAGTTTGTAAGGCATCATAAAGAGAAAATTAAGCAGGCTAAAGAAGCTGTGAAGGAA
AATCTGAAAAAATTCTCAGATTCAGTTAAATCCACTTTCAGACACTTTAAAGATACCACC
AAGAATATCTTTGATGAAAAGGGTAATAAAAGATTTGGTGCTACAAAAGAAGCAGCTGAA
AAACCAAGAACAGTTTTTAGTGACTATTTACATCCACAGTATAAGGCACCTACAGAAAAC
CATCATAATAGAGGCCCTACTATGCAAAATGATGGAAGGAAAGAAAAGCCAGTTCACTTT
AAAGAATTCAGAAAAAATACAAATTCAAAGAAATGCAGTCCTGGGCATGATTGTAGAGAA
AATTCTCATTCTTTCAGAAAGGCTTGTTCTGGTGTATTTGATTGTGCTCAACAAGAGTCC
ATGAGCCTTTTTAACACAGTGGTGAATCCTATAAGGATGGATGAATTTAGACAGATAATT
CAAAGGTACATGTTAAAAGAACTGGATACTTTTTGTCACTGGAACGAACTTGATCAGTTC
ATCAATAAGTTTTTCCTAAACGGTGTCTTTATACATGATCAGAAGCTCTTCACTGACTTT
GTTAATGATGTTAAAGATTATCTTAGAAACATGAAGGAATATGAAGTAGATAATGATGGA
GTATTTGAGAAGTTGGATGAATATATATATAGACACTTCTTTGGTCACACTTTTTCCCCT
CCATATGGACCCAGGTCGGTTTACATAAAACCGTGTCATTACAGTAGTTTGTAA
Protein Properties
Number of Residues 757
Molecular Weight 87339.7
Theoretical pI 5.78
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 218-238
Protein Sequence
>Cell cycle progression protein 1
MSENSSDSDSSCGWTVISHEGSDIEMLNSVTPTDSCEPAPECSSLEQEELQALQIEQGES
SQNGTVLMEETAYPALEETSSTIEAEEQKIPEDSIYIGTASDDSDIVTLEPPKLEEIGNQ
EVVIVEEAQSSEDFNMGSSSSSQYTFCQPETVFSSQPSDDESSSDETSNQPSPAFRRRRA
RKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNKCVILALVIAISMGFGHFYGTIQI
QKRQQLVRKIHEDELNDMKDYLSQCQQEQESFIDYKSLKENLARCWTLTEAEKMSFETQK
TNLATENQYLRVSLEKEEKALSSLQEELNKLREQIRILEDKGTSTELVKENQKLKQHLEE
EKQKKHSFLSQRETLLTEAKMLKRELERERLVTTALRGELQQLSGSQLHGKSDSPNVYTE
KKEIAILRERLTELERKLTFEQQRSDLWERLYVEAKDQNGKQGTDGKKKGGRGSHRAKNK
SKETFLGSVKETFDAMKNSTKEFVRHHKEKIKQAKEAVKENLKKFSDSVKSTFRHFKDTT
KNIFDEKGNKRFGATKEAAEKPRTVFSDYLHPQYKAPTENHHNRGPTMQNDGRKEKPVHF
KEFRKNTNSKKCSPGHDCRENSHSFRKACSGVFDCAQQESMSLFNTVVNPIRMDEFRQII
QRYMLKELDTFCHWNELDQFINKFFLNGVFIHDQKLFTDFVNDVKDYLRNMKEYEVDNDG
VFEKLDEYIYRHFFGHTFSPPYGPRSVYIKPCHYSSL
GenBank ID Protein 75677585
UniProtKB/Swiss-Prot ID Q9ULG6
UniProtKB/Swiss-Prot Entry Name CCPG1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_004748.3
GeneCard ID CCPG1
GenAtlas ID CCPG1
HGNC ID HGNC:24227
References
General References
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