Hmdb loader

Showing Protein Visinin-like protein 1 (HMDBP08101)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP08101
Secondary Accession Numbers
  • 13812
Name Visinin-like protein 1
Synonyms
  1. HLP3
  2. Hippocalcin-like protein 3
  3. VILIP
  4. VLP-1
Gene Name VSNL1
Protein Type Unknown
Biological Properties
General Function Involved in calcium ion binding
Specific Function Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner
Pathways Not Available
Reactions Not Available
GO Classification
Function
ion binding
cation binding
metal ion binding
binding
calcium ion binding
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:2
Locus 2p24.3
SNPs VSNL1
Gene Sequence 
>576 bp
ATGGGGAAGCAGAATAGCAAACTGGCCCCTGAAGTGATGGAGGACCTGGTGAAGAGCACA
GAGTTTAATGAGCATGAACTCAAGCAGTGGTACAAAGGATTTCTCAAGGACTGTCCAAGT
GGGAGGCTAAATCTCGAGGAATTTCAGCAGCTCTATGTGAAGTTCTTTCCTTATGGAGAC
GCCTCCAAGTTTGCCCAGCATGCCTTCCGAACCTTCGACAAGAATGGGGACGGCACCATT
GACTTCCGAGAGTTCATCTGCGCTCTGTCCATCACCTCCAGGGGCAGCTTTGAGCAGAAG
CTGAACTGGGCCTTCAATATGTATGACCTGGATGGTGATGGCAAGATCACCCGAGTGGAG
ATGCTGGAGATCATCGAGGCTATCTACAAAATGGTAGGCACTGTGATCATGATGAAAAAG
AATGAGGATGGCCTGACGCCTGAGCAGCGAGTAGACAAGATTTTCAGCAAGAAGGATAAG
AACAAAGATGACCAGATTACACTGGATGAATTCAAAGAAGCTGCAAAGAGCGACCCTTCC
ATTGTATTACTTCTGCAGTGCGACATCCAGAAATGA
Protein Properties
Number of Residues 191
Molecular Weight 22142.2
Theoretical pI 4.76
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence 
>Visinin-like protein 1
MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD
ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE
MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS
IVLLLQCDIQK
GenBank ID Protein 6440479
UniProtKB/Swiss-Prot ID P62760
UniProtKB/Swiss-Prot Entry Name VISL1_HUMAN
PDB IDs Not Available
GenBank Gene ID AB001104
GeneCard ID VSNL1
GenAtlas ID VSNL1
HGNC ID HGNC:12722
References
General References
  1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
  2. Kobayashi M, Sakai E, Furuta Y, Takamatsu K: Isolation of two human cDNAs, HLP3 and HLP4, homologous to the neuron-specific calcium-binding protein genes. DNA Seq. 1998;9(3):171-6. [PubMed:10520747 ]
  3. Polymeropoulos MH, Ide S, Soares MB, Lennon GG: Sequence characterization and genetic mapping of the human VSNL1 gene, a homologue of the rat visinin-like peptide RNVP1. Genomics. 1995 Sep 1;29(1):273-5. [PubMed:8530085 ]
  4. Lee JM, Blennow K, Andreasen N, Laterza O, Modur V, Olander J, Gao F, Ohlendorf M, Ladenson JH: The brain injury biomarker VLP-1 is increased in the cerebrospinal fluid of Alzheimer disease patients. Clin Chem. 2008 Oct;54(10):1617-23. doi: 10.1373/clinchem.2008.104497. Epub 2008 Aug 14. [PubMed:18703769 ]