| Identification |
|---|
| HMDB Protein ID
| HMDBP07851 |
| Secondary Accession Numbers
| |
| Name
| Pentraxin-4 |
| Synonyms
|
Not Available
|
| Gene Name
| PTX4 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Involved in metal ion binding |
| Specific Function
| Not Available |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Secreted (Potential)
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 16p13.3 |
| SNPs
| PTX4 |
| Gene Sequence
|
>1422 bp
ATGGGGAGTGGAAACTGGGAGGTCACAGGTCCACCTTGTGGCAGTCGGTGTGAACGGCCT
CCCGGACTCCCACGCGGGGTCCACGGACAGTTCCGGAGTGCTGTGGGCCTGTCGGGCCTG
CGCTGGTTCCGGAGATTCCAGGAGGTGACCTGGACACACCTGCAGAACATCGCCAGCAAC
TACAACGTGTCCTACAACGTTGACGTCCGGTTCCGGAGCCTGGCGGAAGAGAGCCAGGCT
GTGGCTCAGGCAGTCAACCGGTCACAGGCCTCGGTGCAGGGGGAGCTGGCGCAGCTCAAG
GCCTGGGTGAGGAAGCTGCAGCGCCGAGGCCGGAAAGTAGACACGCGGCTGCGGGCCTTG
GACCTCACCCTGGGCGAGAGGAGCCAGCAGCGGGCCCGGGAAAGGAAGGCACACAAGGCC
CAGAGGGACGCCCTGCAGGACTCACTGGCACGCCTGGAGGGCCTCGTCCACAGCCAGGGC
GCCAGGCTGGCTGCTCTGGAGGGGCGGCTGCCCGTGGCCCACCCTGGCACTGCAGCCCTC
GGGCCGGCCCTGGTCCCAACCCCAACCCAGCCTGAGGAGCTGGGCCCGACCTCCCTGAAG
CTTCAGAGGGACAGGCAGGAGCTCCGAGCTGCCTCTGAGCACAGGGGCCCCCCACAGGAC
TCCTCGGCCCCTCTCCAAGGGAGGCGGGAGCCTCCAGCCTCAGGCAGCCATCGGGTACTC
AGTGGGACTGCCCCAAAAGACCCTCGGCAGCAGGCATGGTCCCCCCAGGTGCCAGGAGAG
ATTTGCGGCGTGGGCCCCACCCTCGTTTTCCCAAACGCCTCCACCAGGAACGTGGTCTTC
CTCAGCCCTGGTTTCGTCACTGCCCTGCGAGCCCTGTCCTTCTGCAGCTGGGTCCGCACG
GCCTCCGGCCGCCTGGGCACCCTCCTGTCCTACGCCACCGAGGACAATGACAACAAGCTG
GTGCTGCACGGCCGAGACTCCCTGCTGCCCGGATCCATCCACTTCGTGATCGGGGACCCG
GCCTTCAGGGAGCTGCCCTTGCAGCTGCTGCTGGACGGCCAGTGGCACCACATCTGTGTC
ATCTGGACGTCCACCCAGGGCAGGTACTGGCTCCACGTGGATCGCAGGCTGGTGGCCACC
GGCTCCCGCTTCAGGGAGGGCTATGAGATCCCCCCCGGAGGGTCCCTCGTGCTGGGCCAG
GAACAAGACAGCGTGGGGGGCGGATTCGACAGCTCCGAGGCCTTCGTGGGGAGCATGTCT
GGCTTGGCTATCTGGGATCGGGCGCTGGTTCCCGGGGAAGTTGCAAACCTTGCCATCGGG
AAAGAGTTCCCGACAGGTGCCATCCTGACGCTGGCCAATGCTGCACTAGCAGGCGGATTT
GTGCAGGGGGCCAACTGCACCTGCCTGGAACGCTGTCCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 478 |
| Molecular Weight
| 52339.0 |
| Theoretical pI
| 9.99 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Pentraxin-4
MGCSWRKTLSFFLVFVPIYLHGASSQEAAPVGPRKPFFERLRRLEEQFRRFQEVTWTHLQ
NIASNYNVSYNVDVRFRSLAEESQAVAQAVNRSQASVQGELAQLKAWVRKLQRRGRKVDT
RLRALDLTLGERSQQRARERKAHKAQRDALQDSLARLEGLVHSQGARLAALEGRLPVAHP
GTAALGPALVPTPTQPEELGPTSLKLQRDRQELRAASEHRGPPQDSSAPLQGRREPPASG
SHRVLSGTAPKDPRQQAWSPQVPGEICGVGPTLVFPNASTRNVVFLSPGFVTALRALSFC
SWVRTASGRLGTLLSYATEDNDNKLVLHGRDSLLPGSIHFVIGDPAFRELPLQLLLDGQW
HHICVIWTSTQGRYWLHVDRRLVATGSRFREGYEIPPGGSLVLGQEQDSVGGGFDSSEAF
VGSMSGLAIWDRALVPGEVANLAIGKEFPTGAILTLANAALAGGFVQGANCTCLERCP
|
| External Links |
|---|
| GenBank ID Protein
| 61966763 |
| UniProtKB/Swiss-Prot ID
| Q96A99 |
| UniProtKB/Swiss-Prot Entry Name
| PTX4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| PTX4 |
| GenAtlas ID
| PTX4 |
| HGNC ID
| HGNC:14171 |
| References |
|---|
| General References
| - Daniels RJ, Peden JF, Lloyd C, Horsley SW, Clark K, Tufarelli C, Kearney L, Buckle VJ, Doggett NA, Flint J, Higgs DR: Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. Hum Mol Genet. 2001 Feb 15;10(4):339-52. [PubMed:11157797 ]
- Martinez de la Torre Y, Fabbri M, Jaillon S, Bastone A, Nebuloni M, Vecchi A, Mantovani A, Garlanda C: Evolution of the pentraxin family: the new entry PTX4. J Immunol. 2010 May 1;184(9):5055-64. doi: 10.4049/jimmunol.0901672. Epub 2010 Mar 31. [PubMed:20357257 ]
|
