| Identification |
|---|
| HMDB Protein ID
| HMDBP07743 |
| Secondary Accession Numbers
| |
| Name
| Integrin beta-1-binding protein 2 |
| Synonyms
|
- Melusin
|
| Gene Name
| ITGB1BP2 |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Involved in SH3 domain binding |
| Specific Function
| May play a role during maturation and/or organization of muscles cells |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| ITGB1BP2 |
| Gene Sequence
|
>1044 bp
ATGTCTCTACTCTGTCGTAACAAAGGCTGTGGGCAGCACTTTGACCCTAATACCAACCTT
CCTGATTCCTGTTGCCATCACCCTGGGGTCCCAATCTTCCATGATGCACTTAAGGGTTGG
TCCTGCTGCCGAAAGCGAACTGTAGATTTCTCTGAGTTCTTAAACATCAAGGGCTGTACT
ATGGGACCACACTGTGCTGAGAAGCTTCCTGAGGCCCCTCAACCTGAAGGCCCTGCTACA
AGCAGTTCACTTCAGGAGCAAAAACCTCTGAATGTGATTCCAAAGTCAGCAGAGACCTTG
CGCCGGGAGAGGCCCAAGTCAGAGTTGCCTCTGAAGCTGCTGCCGCTAAATATATCCCAA
GCCCTGGAAATGGCATTGGAACAGAAGGAATTAGACCAGGAACCTGGGGCAGGACTTGAC
AGTCTGATCCGGACTGGTTCCAGCTGCCAGAACCCAGGATGTGATGCTGTTTACCAAGGC
CCTGAGAGTGATGCTACTCCATGTACCTACCACCCAGGAGCACCCCGATTCCATGAGGGG
ATGAAGTCTTGGAGCTGTTGTGGCATCCAGACCCTGGATTTTGGGGCATTCTTGGCACAA
CCAGGGTGCAGAGTCGGTAGACATGACTGGGGGAAGCAGCTCCCAGCATCTTGCCGCCAT
GATTGGCACCAGACAGATTCCTTAGTAGTGGTGACTGTATATGGCCAGATTCCACTTCCT
GCGTTTAACTGGGTGAAGGCCAGTCAAACTGAGCTTCATGTCCACATTGTCTTTGATGGT
AACCGTGTGTTCCAAGCACAGATGAAGCTCTGGGGGGTCATAAACGTGGAGCAGAGCTCT
GTCTTCTTGATGCCATCTCGGGTTGAAATCTCCCTGGTCAAGGCTGACCCAGGATCCTGG
GCCCAGCTGGAGCACCCTGATGCACTAGCTAAGAAGGCTAGGGCAGGGGTTGTGTTAGAG
ATGGATGAGGAAGAATCTGACGATTCAGATGATGATCTGAGCTGGACAGAGGAGGAGGAA
GAGGAGGAAGCAATGGGGGAATAG
|
| Protein Properties |
|---|
| Number of Residues
| 347 |
| Molecular Weight
| 38381.9 |
| Theoretical pI
| 4.81 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Integrin beta-1-binding protein 2
MSLLCRNKGCGQHFDPNTNLPDSCCHHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCT
MGPHCAEKLPEAPQPEGPATSSSLQEQKPLNVIPKSAETLRRERPKSELPLKLLPLNISQ
ALEMALEQKELDQEPGAGLDSLIRTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEG
MKSWSCCGIQTLDFGAFLAQPGCRVGRHDWGKQLPASCRHDWHQTDSLVVVTVYGQIPLP
AFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVFLMPSRVEISLVKADPGSW
AQLEHPDALAKKARAGVVLEMDEEESDDSDDDLSWTEEEEEEEAMGE
|
| External Links |
|---|
| GenBank ID Protein
| 17224233 |
| UniProtKB/Swiss-Prot ID
| Q9UKP3 |
| UniProtKB/Swiss-Prot Entry Name
| ITBP2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF110225 |
| GeneCard ID
| ITGB1BP2 |
| GenAtlas ID
| ITGB1BP2 |
| HGNC ID
| HGNC:6154 |
| References |
|---|
| General References
| - Brancaccio M, Guazzone S, Menini N, Sibona E, Hirsch E, De Andrea M, Rocchi M, Altruda F, Tarone G, Silengo L: Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain. J Biol Chem. 1999 Oct 8;274(41):29282-8. [PubMed:10506186 ]
|
