Showing Protein Calpain-12 (HMDBP07541)
Identification | ||||||||||||||||||||||
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HMDB Protein ID | HMDBP07541 | |||||||||||||||||||||
Secondary Accession Numbers |
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Name | Calpain-12 | |||||||||||||||||||||
Synonyms |
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Gene Name | CAPN12 | |||||||||||||||||||||
Protein Type | Unknown | |||||||||||||||||||||
Biological Properties | ||||||||||||||||||||||
General Function | Involved in calcium-dependent cysteine-type endopeptidase activity | |||||||||||||||||||||
Specific Function | Calcium-regulated non-lysosomal thiol-protease | |||||||||||||||||||||
Pathways | Not Available | |||||||||||||||||||||
Reactions | Not Available | |||||||||||||||||||||
GO Classification |
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Cellular Location |
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Gene Properties | ||||||||||||||||||||||
Chromosome Location | Chromosome:1 | |||||||||||||||||||||
Locus | 19q13.2 | |||||||||||||||||||||
SNPs | CAPN12 | |||||||||||||||||||||
Gene Sequence |
>2160 bp ATGGCATCCAGCAGTGGGAGGGTCACCATCCAGCTCGTGGATGAGGAGGCTGGGGTCGGA GCCGGGCGCCTGCAGCTTTTTCGGGGCCAGAGCTATGAGGCAATTCGGGCAGCCTGCCTG GATTCGGGGATCCTGTTCCGCGACCCTTACTTCCCTGCTGGCCCTGATGCCCTTGGCTAT GACCAGCTGGGGCCGGACTCGGAGAAGGCCAAAGGCGTGAAATGGATGAGGCCCCATGAG TTCTGTGCTGAGCCGAAGTTCATCTGTGAAGACATGAGCCGCACAGACGTGTGTCAGGGG AGCCTGGGTAACTGCTGGTTCCTTGCAGCCGCCGCCTCCCTTACTCTGTATCCCCGGCTC CTGCGCCGGGTGGTCCCTCCTGGACAGGATTTCCAGCATGGCTACGCAGGCGTCTTCCAC TTCCAGCTCTGGCAGTTTGGCCGCTGGATGGACGTCGTGGTGGATGACAGGCTGCCCGTG CGTGAGGGGAAGCTGATGTTCGTGCGCTCGGAACAGCGGAATGAGTTCTGGGCCCCACTC CTGGAGAAGGCCTACGCCAAGCTCCACGGCTCCTATGAGGTGATGCGGGGCGGCCACATG AATGAGGCTTTTGTGGATTTCACAGGCGGCGTGGGCGAGGTGCTCTATCTGAGACAAAAC AGCATGGGGCTGTTCTCTGCCCTGCGCCATGCCCTGGCCAAGGAGTCCCTCGTGGGCGCC ACTGCCCTGAGTGATCGGGGTGAGTACCGCACAGAAGAGGGCCTGGTAAAGGGACACGCG TATTCCATCACGGGCACACACAAGGTGTTCCTGGGCTTCACCAAGGTGCGGCTGCTGCGG CTGCGGAACCCATGGGGCTGCGTGGAGTGGACGGGGGCCTGGAGCGACAGCTGCCCACGC TGGGACACACTCCCCACCGAGTGCCGCGATGCCCTGCTGGTGAAAAAGGAGGATGGCGAG TTCTGGATGGAGCTGCGGGACTTCCTCCTCCATTTCGACACCGTGCAGATCTGCTCGCTG AGCCCGGAGGTGCTGGGCCCCAGCCCGGAGGGGGGCGGCTGGCACGTCCACACCTTCCAA GGCCGCTGGGTGCGTGGCTTCAACTCCGGCGGGAGCCAGCCTAATGCTGAAACCTTCTGG ACCAATCCTCAGTTCCGTTTAACGCTGCTGGAGCCTGATGAGGAGGATGACGAGGATGAG GAAGGGCCCTGGGGGGGCTGGGGGGCTGCAGGGGCACGGGGCCCAGCGCGGGGGGGCCGC ACGCCCAAGTGCACGGTCCTTCTGTCCCTCATCCAGCGCAACCGGCGGCGCCTGAGAGCC AAGGGCCTCACTTACCTCACCGTTGGCTTCCACGTGTTCCAGATTCCAGAGGAGCTGCTG GGCCTCTGGGATTCCCCGCGCAGCCATGCGCTCCTGCCCCGGCTGCTGCGCGCCGACCGC TCGCCCCTCAGCGCCCGCCGCGACGTGACCCGCCGCTGCTGCCTGCGTCCAGGCCACTAC CTGGTGGTGCCGAGCACCGCCCACGCCGGCGACGAGGCTGACTTCACTCTGCGTGTCTTC TCCGAGCGCCGCCACACGGCCGTGGAGATCGACGACGTGATCAGCGCAGACCTGCAGTCT CTCCAGGGCCCCTACCTGCCCCTGGAGCTGGGGTTGGAGCAGCTGTTTCAGGAGCTGGCT GGAGAGGAGGAAGAACTCAATGCCTCTCAGCTCCAGGCCTTACTAAGCATTGCCCTGGAG CCTGCCAGGGCCCATACCTCCACCCCCAGAGAGATCGGGCTCAGGACCTGTGAGCAGCTG CTGCAGTGTTTCGGGCATGGGCAAAGCCTGGCCTTACACCACTTCCAGCAGCTCTGGGGC TACCTCCTGGAGTGGCAGGCCATATTCAACAAGTTCGATGAGGACACCTCTGGAACCATG AACTCCTACGAGCTGAGGCTGGCACTGAATGCAGCAGGCTTCCACCTGAACAACCAGCTG ACCCAGACCCTCACCAGCCGCTACCGGGATAGCCGTCTGCGTGTGGACTTCGAGCGGTTC GTGTCCTGTGTGGCCCACCTCACCTGCATCTTCTGCCACTGCAGCCAGCACCTGGATGGG GGTGAGGGGGTCATCTGCCTGACCCACAGACAGTGGATGGAGGTGGCCACCTTCTCCTAG |
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Protein Properties | ||||||||||||||||||||||
Number of Residues | 719 | |||||||||||||||||||||
Molecular Weight | 81036.2 | |||||||||||||||||||||
Theoretical pI | 6.34 | |||||||||||||||||||||
Pfam Domain Function | ||||||||||||||||||||||
Signals |
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Transmembrane Regions |
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Protein Sequence |
>Calpain-12 MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGY DQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRL LRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPL LEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGA TALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPR WDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQ GRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGR TPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADR SPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQS LQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQL LQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQL TQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS |
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External Links | ||||||||||||||||||||||
GenBank ID Protein | 34534289 | |||||||||||||||||||||
UniProtKB/Swiss-Prot ID | Q6ZSI9 | |||||||||||||||||||||
UniProtKB/Swiss-Prot Entry Name | CAN12_HUMAN | |||||||||||||||||||||
PDB IDs | Not Available | |||||||||||||||||||||
GenBank Gene ID | AK127398 | |||||||||||||||||||||
GeneCard ID | CAPN12 | |||||||||||||||||||||
GenAtlas ID | CAPN12 | |||||||||||||||||||||
HGNC ID | HGNC:13249 | |||||||||||||||||||||
References | ||||||||||||||||||||||
General References |
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