Identification |
HMDB Protein ID
| HMDBP07389 |
Secondary Accession Numbers
| |
Name
| MHC class I antigen |
Synonyms
|
Not Available
|
Gene Name
| HLA-B |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in immune response |
Specific Function
| Not Available |
Pathways
|
Not Available
|
Reactions
| Not Available |
GO Classification
|
Component |
mhc protein complex |
mhc class i protein complex |
membrane |
cell part |
macromolecular complex |
protein complex |
Process |
antigen processing and presentation |
immune system process |
immune response |
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:6 |
Locus
| 6p21.3 |
SNPs
| HLA-B |
Gene Sequence
|
>546 bp
GGTCTCACACCCTCCAGAGGATGTACGGCTGCGACGTGGGGCCGGACGGGCGCCTCCTCC
GCGGGCATGACCAGTCCGCCTACGACGGCAAGGATTACATCGCCCTGAACGAGGACCTGA
GCTCCTGGACCGCGGCGGACACGGCGGCTCAGATCACCCAGCGCAAGTGGGAGGCGGCCC
GTGAGGCGGAGCAGTGGAGAGCCTACCTGGAGGGCCTGTGCGTGGAGTGGCTCCGCAGAT
ACCTGGAGAACGGGAAGGAGACGCTGCAGCGGTCTCACACCCTCCAGAGGATGTACGGCT
GCGACGTGGGGCCGGACGGGCGCCTCCTCCGCGGGCATGACCAGTCCGCCTACGACGGCA
AGGATTACATCGCCCTGAACGAGGACCTGAGCTCCTGGACCGCGGCGGACACGGCGGCTC
AGATCACCCAGCGCAAGTGGGAGGCGGCCCGTGAGGCGGAGCAGTGGAGAGCCTACCTGG
AGGGCCTGTGCGTGGAGTGGCTCCGCAGATACCTGGAGAACGGGAAGGAGACGCTGCAGC
GCGCGG
|
Protein Properties |
Number of Residues
| 181 |
Molecular Weight
| 21058.9 |
Theoretical pI
| 5.13 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>MHC class I antigen
SHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPREEPRAPWIEQEGPEYWD
RNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQRMYGCDVGPDGRLLRGHDQSAYDGK
DYIALNEDLSSWTAADTAAQITQRKWEAAREAEQWRAYLEGLCVEWLRRYLENGKETLQR
A
|
External Links |
GenBank ID Protein
| 1526966 |
UniProtKB/Swiss-Prot ID
| Q95372 |
UniProtKB/Swiss-Prot Entry Name
| Q95372_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| U67749 |
GeneCard ID
| HLA-B |
GenAtlas ID
| HLA-B |
HGNC ID
| HGNC:4932 |
References |
General References
| - Hurley CK, Steiner N, Kosman C, Mitton W, Koester R, Bei M, Bush J, McCormack J, Hahn A, Henson V, Hoyer R, Wade JA, Hartzman RJ, Ng J: Novel HLA-A and HLA-B alleles. Tissue Antigens. 1998 Jul;52(1):84-7. [PubMed:9714480 ]
|