Showing Protein Vitamin K epoxide reductase complex subunit 1 (HMDBP02242)

• 7727

1. Vitamin K1 2,3-epoxide reductase subunit 1

• Acenocoumarol Action Pathway
• Alteplase Action Pathway
• Aminocaproic Acid Action Pathway
• Anistreplase Action Pathway
• Aprotinin Action Pathway
• Ardeparin Action Pathway
• Argatroban Action Pathway
• Bivalirudin Action Pathway
• Coagulation
• Dicoumarol Action Pathway
• Dicumarol Action Pathway
• Enoxaparin Action Pathway
• Fondaparinux Action Pathway
• Heparin Action Pathway
• Lepirudin Action Pathway
• Phenindione Action Pathway
• Phenprocoumon Action Pathway
• Reteplase Action Pathway
• Streptokinase Action Pathway
• Tenecteplase Action Pathway
• Tranexamic Acid Action Pathway
• Ubiquinone and other terpenoid-quinone biosynthesis
• Urokinase Action Pathway
• Vitamin K Metabolism
• Warfarin Action Pathway
• Ximelagatran Action Pathway

1. Endoplasmic reticulum membrane
2. Multi-pass membrane protein

>492 bp
ATGGGCAGCACCTGGGGGAGCCCTGGCTGGGTGCGGCTCGCTCTTTGCCTGACGGGCTTA
GTGCTCTCGCTCTACGCGCTGCACGTGAAGGCGGCGCGCGCCCGGGACCGGGATTACCGC
GCGCTCTGCGACGTGGGCACCGCCATCAGCTGTTCGCGCGTCTTCTCCTCCAGGTGGGGC
AGGGGTTTCGGGCTGGTGGAGCATGTGCTGGGACAGGACAGCATCCTCAATCAATCCAAC
AGCATATTCGGTTGCATCTTCTACACACTACAGCTATTGTTAGGTTGCCTGCGGACACGC
TGGGCCTCTGTCCTGATGCTGCTGAGCTCCCTGGTGTCTCTCGCTGGTTCTGTCTACCTG
GCCTGGATCCTGTTCTTCGTGCTCTATGATTTCTGCATTGTTTGTATCACCACCTATGCT
ATCAACGTGAGCCTGATGTGGCTCAGTTTCCGGAAGGTCCAAGAACCCCAGGGCAAGGCT
AAGAGGCACTGA

• VKOR (PF07884 )

>Vitamin K epoxide reductase complex subunit 1
MGSTWGSPGWVRLALCLTGLVLSLYALHVKAARARDRDYRALCDVGTAISCSRVFSSRWG
RGFGLVEHVLGQDSILNQSNSIFGCIFYTLQLLLGCLRTRWASVLMLLSSLVSLAGSVYL
AWILFFVLYDFCIVCITTYAINVSLMWLSFRKVQEPQGKAKRH

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5. Li T, Chang CY, Jin DY, Lin PJ, Khvorova A, Stafford DW: Identification of the gene for vitamin K epoxide reductase. Nature. 2004 Feb 5;427(6974):541-4. [PubMed:14765195 ]
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7. Tie JK, Nicchitta C, von Heijne G, Stafford DW: Membrane topology mapping of vitamin K epoxide reductase by in vitro translation/cotranslocation. J Biol Chem. 2005 Apr 22;280(16):16410-6. Epub 2005 Feb 16. [PubMed:15716279 ]
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