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Showing Protein Retinol-binding protein 1 (HMDBP02108)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP02108
Secondary Accession Numbers
  • 7590
Name Retinol-binding protein 1
Synonyms
  1. CRBP
  2. CRBP-I
  3. Cellular retinol-binding protein
  4. Cellular retinol-binding protein I
Gene Name RBP1
Protein Type Enzyme
Biological Properties
General Function Involved in binding
Specific Function Intracellular transport of retinol
Pathways Not Available
Reactions Not Available
GO Classification
Function
binding
transporter activity
lipid binding
Process
establishment of localization
transport
Cellular Location
  1. Cytoplasm
Gene Properties
Chromosome Location Chromosome:3
Locus 3q23
SNPs RBP1
Gene Sequence 
>408 bp
ATGCCAGTCGACTTCACTGGGTACTGGAAGATGTTGGTCAACGAGAATTTCGAGGAGTAC
CTGCGCGCCCTCGACGTCAATGTGGCCTTGCGCAAAATCGCCAACTTGCTGAAGCCAGAC
AAAGAGATCGTGCAGGACGGTGACCATATGATCATCCGCACGCTGAGCACTTTTAGGAAC
TACATCATGGACTTCCAAGTTGGGAAGGAGTTTGAGGAGGATCTGACAGGCATAGATGAC
CGCAAGTGCATGACAACAGTGAGCTGGGACGGAGACAAGCTCCAGTGTGTGCAGAAGGGT
GAGAAGGAGGGGCGTGGCTGGACCCAGTGGATCGAGGGTGATGAGCTGCACCTAGAGATG
AGAGTGGAAGGTGTGGTCTGCAAGCAAGTATTCAAGAAGGTGCAGTGA
Protein Properties
Number of Residues 135
Molecular Weight 15850.1
Theoretical pI 4.74
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence 
>Retinol-binding protein 1
MPVDFTGYWKMLVNENFEEYLRALDVNVALRKIANLLKPDKEIVQDGDHMIIRTLSTFRN
YIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLQCVQKGEKEGRGWTQWIEGDELHLEM
RVEGVVCKQVFKKVQ
GenBank ID Protein 190948
UniProtKB/Swiss-Prot ID P09455
UniProtKB/Swiss-Prot Entry Name RET1_HUMAN
PDB IDs
GenBank Gene ID M11433
GeneCard ID RBP1
GenAtlas ID RBP1
HGNC ID HGNC:9919
References
General References
  1. Gerhard DS, Wagner L, Feingold EA, Shenmen CM, Grouse LH, Schuler G, Klein SL, Old S, Rasooly R, Good P, Guyer M, Peck AM, Derge JG, Lipman D, Collins FS, Jang W, Sherry S, Feolo M, Misquitta L, Lee E, Rotmistrovsky K, Greenhut SF, Schaefer CF, Buetow K, Bonner TI, Haussler D, Kent J, Kiekhaus M, Furey T, Brent M, Prange C, Schreiber K, Shapiro N, Bhat NK, Hopkins RF, Hsie F, Driscoll T, Soares MB, Casavant TL, Scheetz TE, Brown-stein MJ, Usdin TB, Toshiyuki S, Carninci P, Piao Y, Dudekula DB, Ko MS, Kawakami K, Suzuki Y, Sugano S, Gruber CE, Smith MR, Simmons B, Moore T, Waterman R, Johnson SL, Ruan Y, Wei CL, Mathavan S, Gunaratne PH, Wu J, Garcia AM, Hulyk SW, Fuh E, Yuan Y, Sneed A, Kowis C, Hodgson A, Muzny DM, McPherson J, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madari A, Young AC, Wetherby KD, Granite SJ, Kwong PN, Brinkley CP, Pearson RL, Bouffard GG, Blakesly RW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Griffith M, Griffith OL, Krzywinski MI, Liao N, Morin R, Palmquist D, Petrescu AS, Skalska U, Smailus DE, Stott JM, Schnerch A, Schein JE, Jones SJ, Holt RA, Baross A, Marra MA, Clifton S, Makowski KA, Bosak S, Malek J: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 2004 Oct;14(10B):2121-7. [PubMed:15489334 ]
  2. Colantuoni V, Cortese R, Nilsson M, Lundvall J, Bavik CO, Eriksson U, Peterson PA, Sundelin J: Cloning and sequencing of a full length cDNA corresponding to human cellular retinol-binding protein. Biochem Biophys Res Commun. 1985 Jul 16;130(1):431-9. [PubMed:2992469 ]
  3. Nilsson MH, Spurr NK, Lundvall J, Rask L, Peterson PA: Human cellular retinol-binding protein gene organization and chromosomal location. Eur J Biochem. 1988 Apr 5;173(1):35-44. [PubMed:3356192 ]
  4. Wei LN, Mertz JR, Goodman DS, Nguyen-Huu MC: Cellular retinoic acid- and cellular retinol-binding proteins: complementary deoxyribonucleic acid cloning, chromosomal assignment, and tissue specific expression. Mol Endocrinol. 1987 Aug;1(8):526-34. [PubMed:2856408 ]
  5. Folli C, Calderone V, Ottonello S, Bolchi A, Zanotti G, Stoppini M, Berni R: Identification, retinoid binding, and x-ray analysis of a human retinol-binding protein. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3710-5. [PubMed:11274389 ]