Showing Protein Lysosomal acid lipase/cholesteryl ester hydrolase (HMDBP00227)

• 5459

1. Acid cholesteryl ester hydrolase
2. Cholesteryl esterase
3. LAL
4. Lipase A
5. Sterol esterase

• 27-Hydroxylase Deficiency
• Alendronate Action Pathway
• Atorvastatin Action Pathway
• Cerebrotendinous Xanthomatosis (CTX)
• Cerivastatin Action Pathway
• CHILD Syndrome
• Cholesteryl ester storage disease
• Chondrodysplasia Punctata II, X Linked Dominant (CDPX2)
• Congenital Bile Acid Synthesis Defect Type II
• Congenital Bile Acid Synthesis Defect Type III
• Desmosterolosis
• Familial Hypercholanemia (FHCA)
• Fluvastatin Action Pathway
• Hyper-IgD syndrome
• Hypercholesterolemia
• Ibandronate Action Pathway
• Lovastatin Action Pathway
• Lysosomal Acid Lipase Deficiency (Wolman Disease)
• Lysosome
• Mevalonic aciduria
• Pamidronate Action Pathway
• Pravastatin Action Pathway
• Primary bile acid biosynthesis
• Risedronate Action Pathway
• Rosuvastatin Action Pathway
• Simvastatin Action Pathway
• Smith-Lemli-Opitz Syndrome (SLOS)
• Steroid biosynthesis
• Steroid Biosynthesis
• Wolman disease
• Zellweger Syndrome
• Zoledronate Action Pathway

1. Lysosome

>1200 bp
ATGAAAATGCGGTTCTTGGGGTTGGTGGTCTGTTTGGTTCTCTGGACCCTGCATTCTGAG
GGGTCTGGAGGGAAACTGACAGCTGTGGATCCTGAAACAAACATGAATGTGAGTGAAATT
ATCTCTTACTGGGGATTCCCTAGTGAGGAATACCTAGTTGAGACAGAAGATGGATATATT
CTGTGCCTTAACCGAATTCCTCATGGGAGGAAGAACCATTCTGACAAAGGTCCCAAACCA
GTTGTCTTCCTGCAACATGGCTTGCTGGCAGATTCTAGTAACTGGGTCACAAACCTTGCC
AACAGCAGCCTGGGCTTCATTCTTGCTGATGCTGGTTTTGACGTGTGGATGGGCAACAGC
AGAGGAAATACCTGGTCTCGGAAACATAAGACACTCTCAGTTTCTCAGGATGAATTCTGG
GCTTTCAGTTATGATGAGATGGCAAAATATGACCTACCAGCTTCCATTAACTTCATTCTG
AATAAAACTGGCCAAGAACAAGTGTATTATGTGGGTCATTCTCAAGGCACCACTATAGGT
TTTATAGCATTTTCACAGATCCCTGAGCTGGCTAAAAGGATTAAAATGTTTTTTGCCCTG
GGTCCTGTGGCTTCCGTCGCCTTCTGTACTAGCCCTATGGCCAAATTAGGACGATTACCA
GATCATCTCATTAAGGACTTATTTGGAGACAAAGAATTTCTTCCCCAGAGTGCGTTTTTG
AAGTGGCTGGGTACCCACGTTTGCACTCATGTCATACTGAAGGAGCTCTGTGGAAATCTC
TGTTTTCTTCTGTGTGGATTTAATGAGAGAAATTTAAATATGTCTAGAGTGGATGTATAT
ACAACACATTCTCCTGCTGGAACTTCTGTGCAAAACATGTTACACTGGAGCCAGGCTGTT
AAATTCCAAAAGTTTCAAGCCTTTGACTGGGGAAGCAGTGCCAAGAATTATTTTCATTAC
AACCAGAGTTATCCTCCCACATACAATGTGAAGGACATGCTTGTGCCGACTGCAGTCTGG
AGCGGGGGTCACGACTGGCTTGCAGATGTCTACGACGTCAATATCTTACTGACTCAGATC
ACCAACTTGGTGTTCCATGAGAGCATTCCGGAATGGGAGCATCTTGACTTCATTTGGGGC
CTGGATGCCCCTTGGAGGCTTTATAATAAAATTATTAATCTAATGAGGAGATATCAGTGA

• Abhydro_lipase (PF04083 )
• Abhydrolase_1 (PF00561 )

>Lysosomal acid lipase/cholesteryl ester hydrolase
MKMRFLGLVVCLVLWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYI
LCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNS
RGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIG
FIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLFGDKEFLPQSAFL
KWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAV
KFQKFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQI
TNLVFHESIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ

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