Hmdb loader

HMDB0015607 (Lucanthone) Protein Associations

Displaying all 2 metabolite protein links
HMDBP ID Name UniProt ID Gene Name Locus Type References
HMDBP10647DNA-(apurinic or apyrimidinic site) lyaseP27695 APEX114q11.2Enzyme
  1. Luo M, Kelley MR: Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone. Anticancer Res. 2004 Jul-Aug;24(4):2127-34. [PubMed:15330152 ]
HMDBP10697DNA topoisomerase 2-alphaP11388 TOP2A17q21-q22Enzyme
  1. Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
  2. Bases RE, Mendez F: Topoisomerase inhibition by lucanthone, an adjuvant in radiation therapy. Int J Radiat Oncol Biol Phys. 1997 Mar 15;37(5):1133-7. [PubMed:9169823 ]
  3. Dassonneville L, Bailly C: Stimulation of topoisomerase II-mediated DNA cleavage by an indazole analogue of lucanthone. Biochem Pharmacol. 1999 Oct 15;58(8):1307-12. [PubMed:10487533 ]
Displaying all 2 metabolite protein links