HMDBP01551 | Cytochrome P450 2F1 | P24903 | CYP2F1 | 19q13.2 | Unknown | Not Available |
HMDBP01552 | Cytochrome P450 4X1 | Q8N118 | CYP4X1 | 1 | Unknown | Not Available |
HMDBP01553 | Cytochrome P450 2B6 | P20813 | CYP2B6 | 19q13.2 | Unknown | Not Available |
HMDBP01554 | Cytochrome P450 3A5 | P20815 | CYP3A5 | 7q21.1 | Unknown | Not Available |
HMDBP01556 | Cytochrome P450 2A13 | Q16696 | CYP2A13 | 19q13.2 | Unknown | Not Available |
HMDBP01557 | Cytochrome P450 3A7 | P24462 | CYP3A7 | 7q21-q22.1 | Unknown | - Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. doi: 10.1093/nar/gkp970. Epub 2009 Nov 24. [PubMed:19934256 ]
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HMDBP01558 | Cytochrome P450 4B1 | P13584 | CYP4B1 | 1p34-p12 | Unknown | Not Available |
HMDBP01559 | Cytochrome P450 4Z1 | Q86W10 | CYP4Z1 | 1p33 | Unknown | Not Available |
HMDBP01560 | Cytochrome P450 1A2 | P05177 | CYP1A2 | 15q24.1 | Unknown | Not Available |
HMDBP01561 | Cytochrome P450 19A1 | P11511 | CYP19A1 | 15q21.1 | Unknown | Not Available |
HMDBP01562 | Cytochrome P450 2C8 | P10632 | CYP2C8 | 10q23.33 | Unknown | Not Available |
HMDBP01563 | Cytochrome P450 2S1 | Q96SQ9 | CYP2S1 | 19q13.1 | Unknown | Not Available |
HMDBP01565 | Cytochrome P450 2J2 | P51589 | CYP2J2 | 1p31.3-p31.2 | Unknown | Not Available |
HMDBP01566 | Cytochrome P450 2A7 | P20853 | CYP2A7 | 19q13.2 | Unknown | Not Available |
HMDBP01567 | Cytochrome P450 2A6 | P11509 | CYP2A6 | 19q13.2 | Unknown | Not Available |
HMDBP02444 | Delta-type opioid receptor | P41143 | OPRD1 | 1p36.1-p34.3 | Unknown | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
- Ortiz MI, Castro-Olguin J, Pena-Samaniego N, Castaneda-Hernandez G: Probable activation of the opioid receptor-nitric oxide-cyclic GMP-K+ channels pathway by codeine. Pharmacol Biochem Behav. 2005 Dec;82(4):695-703. Epub 2006 Jan 4. [PubMed:16386786 ]
- Mignat C, Wille U, Ziegler A: Affinity profiles of morphine, codeine, dihydrocodeine and their glucuronides at opioid receptor subtypes. Life Sci. 1995;56(10):793-9. [PubMed:7885194 ]
- Loghin F, Popa DS, Socaciu C: Influence of glutethimide on rat brain mononucleotides by sub-chronic codeine treatment. J Cell Mol Med. 2001 Oct-Dec;5(4):409-16. [PubMed:12067475 ]
- Advenier C, Girard V, Naline E, Vilain P, Emonds-Alt X: Antitussive effect of SR 48968, a non-peptide tachykinin NK2 receptor antagonist. Eur J Pharmacol. 1993 Nov 30;250(1):169-71. [PubMed:8119316 ]
- Karlsson JA, Lanner AS, Persson CG: Airway opioid receptors mediate inhibition of cough and reflex bronchoconstriction in guinea pigs. J Pharmacol Exp Ther. 1990 Feb;252(2):863-8. [PubMed:2156065 ]
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HMDBP02643 | Mu-type opioid receptor | P35372 | OPRM1 | 6q24-q25 | Unknown | - Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. [PubMed:11752352 ]
- Grond S, Sablotzki A: Clinical pharmacology of tramadol. Clin Pharmacokinet. 2004;43(13):879-923. [PubMed:15509185 ]
- Takahama K, Shirasaki T: Central and peripheral mechanisms of narcotic antitussives: codeine-sensitive and -resistant coughs. Cough. 2007 Jul 9;3:8. [PubMed:17620111 ]
- Freissmuth M, Beindl W, Kratzel M: Binding and structure-activity-relation of benzo[f]isoquinoline- and norcodeinone-derivatives at mu-opioid receptors in the rat cerebral cortex. Br J Pharmacol. 1993 Dec;110(4):1429-36. [PubMed:8306082 ]
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HMDBP07348 | UDP-glucuronosyltransferase 2A3 | Q6UWM9 | UGT2A3 | 4q13.2 | Enzyme | Not Available |
HMDBP07417 | Cytochrome P450, family 1, subfamily A, polypeptide 1 | A0N0X8 | CYP1A1 | 15q24.1 | Enzyme | Not Available |
HMDBP07856 | Kappa-type opioid receptor | P41145 | OPRK1 | 8q11.2 | Unknown | - Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
- Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
- Takahama K, Shirasaki T: Central and peripheral mechanisms of narcotic antitussives: codeine-sensitive and -resistant coughs. Cough. 2007 Jul 9;3:8. [PubMed:17620111 ]
- Mignat C, Wille U, Ziegler A: Affinity profiles of morphine, codeine, dihydrocodeine and their glucuronides at opioid receptor subtypes. Life Sci. 1995;56(10):793-9. [PubMed:7885194 ]
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HMDBP09238 | HCG2039726, isoform CRA_f | Q5DT02 | UGT1A10 | 2q37 | Enzyme | Not Available |
HMDBP09239 | HCG2039726, isoform CRA_e | Q5DSZ6 | UGT1A8 | 2q37 | Enzyme | Not Available |
HMDBP09240 | UDP glycosyltransferase 1 family polypeptide A7 | Q5DSZ7 | UGT1A7 | 2q37 | Enzyme | Not Available |
HMDBP09335 | Cytochrome P450 2D6 | Q6NWU0 | CYP2D6 | 22q13.1 | Enzyme | Not Available |