| Identification |
|---|
| HMDB Protein ID
| HMDBP13462 |
| Secondary Accession Numbers
| None |
| Name
| Phosphoribosylformylglycinamidine cyclo-ligase |
| Synonyms
|
- AIR synthase
- AIRS
- Phosphoribosyl-aminoimidazole synthetase
|
| Gene Name
| PURM |
| Protein Type
| Unknown |
| Biological Properties |
|---|
| General Function
| Not Available |
| Specific Function
| Not Available |
| Pathways
|
- Biosynthesis of secondary metabolites
- IMP biosynthesis via de novo pathway
- Purine metabolism
|
| Reactions
| Not Available |
| GO Classification
|
| Biological Process |
| 'de novo' IMP biosynthetic process |
| Cellular Component |
| cytoplasm |
| Molecular Function |
| ATP binding |
| phosphoribosylformylglycinamidine cyclo-ligase activity |
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
Not Available
|
| Protein Properties |
|---|
| Number of Residues
| 340 |
| Molecular Weight
| 36563.725 |
| Theoretical pI
| 4.863 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
Not Available
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q1JE80 |
| UniProtKB/Swiss-Prot Entry Name
| PUR5_STRPB |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| Not Available |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| - Beres SB, Richter EW, Nagiec MJ, Sumby P, Porcella SF, DeLeo FR, Musser JM: Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus. Proc Natl Acad Sci U S A. 2006 May 2;103(18):7059-64. doi: 10.1073/pnas.0510279103. Epub 2006 Apr 24. [PubMed:16636287 ]
|
