Hmdb loader

Showing Protein Thiamine transporter THTR-1 (HMDBP10779)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP10779
Secondary Accession Numbers
  • 17048
Name Thiamine transporter THTR-1
Synonyms Not Available
Gene Name SLC19A2
Protein Type Unknown
Biological Properties
General Function Involved in folic acid binding
Specific Function Not Available
Pathways Not Available
Reactions Not Available
GO Classification
Component
membrane
cell part
Function
active transmembrane transporter activity
binding
transmembrane transporter activity
folic acid binding
carboxylic acid binding
amino acid binding
transporter activity
secondary active transmembrane transporter activity
reduced folate carrier activity
Process
establishment of localization
transport
Cellular Location Not Available
Gene Properties
Chromosome Location Chromosome:1
Locus 1q23.3
SNPs SLC19A2
Gene Sequence 
>204 bp
ATGGATGTGCCCGGCCCGGTGTCTCGGCGGGCGGCGGCGGCGGCGGCCACTGTGCTCCTG
CGGACCGCTCGGGTCCGTCGCGAATGCTGGTTCTTGCCGACCGCGCTGCTCTGCGCCTAC
GGCTTCTTCGCCAGCCTCAGGCCGTCCGAGCTCTTCCTGACCCCGTACCTGCTGGGGCCG
GACAAGAACCTGACCGAGAGGGAG
Protein Properties
Number of Residues 68
Molecular Weight 7567.7
Theoretical pI 9.39
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence 
>Thiamine transporter THTR-1
MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSELFLTPYLLGP
DKNLTERE
GenBank ID Protein 30962027
UniProtKB/Swiss-Prot ID Q7Z7J1
UniProtKB/Swiss-Prot Entry Name Q7Z7J1_HUMAN
PDB IDs Not Available
GenBank Gene ID AY288293
GeneCard ID SLC19A2
GenAtlas ID SLC19A2
HGNC ID HGNC:10938
References
General References
  1. Lagarde WH, Underwood LE, Moats-Staats BM, Calikoglu AS: Novel mutation in the SLC19A2 gene in an African-American female with thiamine-responsive megaloblastic anemia syndrome. Am J Med Genet A. 2004 Mar 15;125A(3):299-305. [PubMed:14994241 ]