Hmdb loader
Identification
HMDB Protein ID HMDBP09198
Secondary Accession Numbers
  • 14972
Name RNA pseudouridylate synthase domain-containing protein 1
Synonyms
  1. Ribosomal large subunit pseudouridine synthase C-like protein
Gene Name RPUSD1
Protein Type Enzyme
Biological Properties
General Function Involved in RNA binding
Specific Function Not Available
Pathways Not Available
Reactions Not Available
GO Classification
Function
binding
catalytic activity
nucleic acid binding
isomerase activity
pseudouridine synthase activity
intramolecular transferase activity
rna binding
Process
rna metabolic process
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
rna modification
pseudouridine synthesis
Cellular Location
  1. Cytoplasmic
Gene Properties
Chromosome Location Chromosome:1
Locus 16p13.3
SNPs RPUSD1
Gene Sequence
>939 bp
ATGGAGCCAGGCAGCGTGGAGAACCTGTCCATCGTGTACCGGAGCCGCGACTTCCTGGTG
GTCAACAAGCACTGGGACGTTCGCATTGACAGCAAGGCGTGGCGGGAGACTCTGACCCTG
CAGAAGCAGCTGCGGTACCGCTTTCCCGAGCTGGCCGACCCTGACACCTGCTACGGGTTC
AGGTTCTGCCACCAGCTGGATTTCTCCACCAGCGGGGCGCTGTGCGTGGCCCTAAACAAG
GCAGCCGCCGGCAGCGCGTACAGGTGCTTCAAGGAGCGGCGCGTGACCAAGGCTTACCTG
GCATTGCTGCGGGGGCACATCCAGGAGAGCCGGGTAACCATCAGCCATGCCATTGGCAGG
AACAGCACGGAGGGCCGGGCCCACACCATGTGCATCGAGGGCTCGCAGGGTTGTGAGAAC
CCAAAGCCAAGCCTCACAGATCTCGTGGTTCTGGAACACGGGCTGTACGCAGGCGATCCT
GTCTCCAAAGTGCTGCTGAAGCCGCTCACGGGCCGGACACACCAGCTGCGCGTGCACTGC
AGTGCCCTGGGCCACCCCGTGGTGGGCGACCTGACCTACGGAGAAGTCTCGGGCCGGGAG
GACCGGCCGTTCAGAATGATGCTGCACGCTTTCTACCTGCGCATCCCCACGGACACCGAG
TGTGTGGAGGTCTGCACGCCTGACCCCTTCCTGCCCTCCCTGGATGCCTGCTGGAGCCCC
CACACACTGCTGCAGTCGCTGGACCAGCTCGTGCAGGCCTTACGGGCCACCCCCGACCCT
GACCCCGAGGATAGGGGCCCCAGGCCAGGCAGCCCCTCCGCACTCCTGCCTGGGCCCGGC
CGGCCTCCTCCACCCCCAACCAAGCCCCCTGAGACTGAGGCACAGCGGGGCCCCTGCCTG
CAGTGGCTGTCGGAGTGGACGCTGGAACCGGACAGCTGA
Protein Properties
Number of Residues 312
Molecular Weight 34755.2
Theoretical pI 7.06
Pfam Domain Function
Signals
  • None
Transmembrane Regions
  • None
Protein Sequence
>RNA pseudouridylate synthase domain-containing protein 1
MEPGSVENLSIVYRSRDFLVVNKHWDVRIDSKAWRETLTLQKQLRYRFPELADPDTCYGF
RFCHQLDFSTSGALCVALNKAAAGSAYRCFKERRVTKAYLALLRGHIQESRVTISHAIGR
NSTEGRAHTMCIEGSQGCENPKPSLTDLVVLEHGLYAGDPVSKVLLKPLTGRTHQLRVHC
SALGHPVVGDLTYGEVSGREDRPFRMMLHAFYLRIPTDTECVEVCTPDPFLPSLDACWSP
HTLLQSLDQLVQALRATPDPDPEDRGPRPGSPSALLPGPGRPPPPPTKPPETEAQRGPCL
QWLSEWTLEPDS
GenBank ID Protein 17158025
UniProtKB/Swiss-Prot ID Q9UJJ7
UniProtKB/Swiss-Prot Entry Name RUSD1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_058192.2
GeneCard ID RPUSD1
GenAtlas ID RPUSD1
HGNC ID HGNC:14173
References
General References
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  2. Martin J, Han C, Gordon LA, Terry A, Prabhakar S, She X, Xie G, Hellsten U, Chan YM, Altherr M, Couronne O, Aerts A, Bajorek E, Black S, Blumer H, Branscomb E, Brown NC, Bruno WJ, Buckingham JM, Callen DF, Campbell CS, Campbell ML, Campbell EW, Caoile C, Challacombe JF, Chasteen LA, Chertkov O, Chi HC, Christensen M, Clark LM, Cohn JD, Denys M, Detter JC, Dickson M, Dimitrijevic-Bussod M, Escobar J, Fawcett JJ, Flowers D, Fotopulos D, Glavina T, Gomez M, Gonzales E, Goodstein D, Goodwin LA, Grady DL, Grigoriev I, Groza M, Hammon N, Hawkins T, Haydu L, Hildebrand CE, Huang W, Israni S, Jett J, Jewett PB, Kadner K, Kimball H, Kobayashi A, Krawczyk MC, Leyba T, Longmire JL, Lopez F, Lou Y, Lowry S, Ludeman T, Manohar CF, Mark GA, McMurray KL, Meincke LJ, Morgan J, Moyzis RK, Mundt MO, Munk AC, Nandkeshwar RD, Pitluck S, Pollard M, Predki P, Parson-Quintana B, Ramirez L, Rash S, Retterer J, Ricke DO, Robinson DL, Rodriguez A, Salamov A, Saunders EH, Scott D, Shough T, Stallings RL, Stalvey M, Sutherland RD, Tapia R, Tesmer JG, Thayer N, Thompson LS, Tice H, Torney DC, Tran-Gyamfi M, Tsai M, Ulanovsky LE, Ustaszewska A, Vo N, White PS, Williams AL, Wills PL, Wu JR, Wu K, Yang J, Dejong P, Bruce D, Doggett NA, Deaven L, Schmutz J, Grimwood J, Richardson P, Rokhsar DS, Eichler EE, Gilna P, Lucas SM, Myers RM, Rubin EM, Pennacchio LA: The sequence and analysis of duplication-rich human chromosome 16. Nature. 2004 Dec 23;432(7020):988-94. [PubMed:15616553 ]
  3. Daniels RJ, Peden JF, Lloyd C, Horsley SW, Clark K, Tufarelli C, Kearney L, Buckle VJ, Doggett NA, Flint J, Higgs DR: Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. Hum Mol Genet. 2001 Feb 15;10(4):339-52. [PubMed:11157797 ]