Hmdb loader

HMDBP00421 (Methionine synthase reductase) Metabolite Associations

Displaying all 11 metabolite protein links
HMDB ID Name CAS NumberStructureFormula Average Mass
Monoisotopic Mass 		References
HMDB0000217NADP53-59-8ThumbC21H28N7O17P3743.405
743.075452041		Not Available
HMDB0000221NADPH53-57-6ThumbC21H30N7O17P3745.4209
745.091102105		Not Available
HMDB0000607Cyanocobalamin68-19-9ThumbC63H89CoN14O14P1356.3731
1355.575230332
  1. O'Leary VB, Mills JL, Pangilinan F, Kirke PN, Cox C, Conley M, Weiler A, Peng K, Shane B, Scott JM, Parle-McDermott A, Molloy AM, Brody LC: Analysis of methionine synthase reductase polymorphisms for neural tube defects risk association. Mol Genet Metab. 2005 Jul;85(3):220-7. Epub 2005 Mar 17. [PubMed:15979034 ]
  2. Gueant-Rodriguez RM, Juilliere Y, Candito M, Adjalla CE, Gibelin P, Herbeth B, Van Obberghen E, Gueant JL: Association of MTRRA66G polymorphism (but not of MTHFR C677T and A1298C, MTRA2756G, TCN C776G) with homocysteine and coronary artery disease in the French population. Thromb Haemost. 2005 Sep;94(3):510-5. [PubMed:16268464 ]
  3. Miriuka SG, Langman LJ, Evrovski J, Miner SE, D'Mello N, Delgado DH, Wong BY, Ross HJ, Cole DE: Genetic polymorphisms predisposing to hyperhomocysteinemia in cardiac transplant patients. Transpl Int. 2005 Jan;18(1):29-35. [PubMed:15612980 ]
  4. Berkun Y, Abou Atta I, Rubinow A, Orbach H, Levartovsky D, Aamar S, Arbel O, Dresner-Pollak R, Friedman G, Ben-Yehuda A: 2756GG genotype of methionine synthase reductase gene is more prevalent in rheumatoid arthritis patients treated with methotrexate and is associated with methotrexate-induced nodulosis. J Rheumatol. 2007 Aug;34(8):1664-9. Epub 2007 Jul 1. [PubMed:17611986 ]
  5. van der Linden IJ, den Heijer M, Afman LA, Gellekink H, Vermeulen SH, Kluijtmans LA, Blom HJ: The methionine synthase reductase 66A>G polymorphism is a maternal risk factor for spina bifida. J Mol Med (Berl). 2006 Dec;84(12):1047-54. Epub 2006 Oct 6. [PubMed:17024475 ]
HMDB0000696Methionine63-68-3ThumbC5H11NO2S149.211
149.051049291
  1. Kim DJ, Park BL, Koh JM, Kim GS, Kim LH, Cheong HS, Shin HD, Hong JM, Kim TH, Shin HI, Park EK, Kim SY: Methionine synthase reductase polymorphisms are associated with serum osteocalcin levels in postmenopausal women. Exp Mol Med. 2006 Oct 31;38(5):519-24. [PubMed:17079868 ]
  2. Tvedegaard KC, Rudiger NS, Pedersen BN, Moller J: Detection of MTRR 66A-->G polymorphism using the real-time polymerase chain reaction machine LightCycler for determination of composition of allele after restriction cleavage. Scand J Clin Lab Invest. 2006;66(8):685-93. [PubMed:17101561 ]
  3. Elmore CL, Wu X, Leclerc D, Watson ED, Bottiglieri T, Krupenko NI, Krupenko SA, Cross JC, Rozen R, Gravel RA, Matthews RG: Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. Mol Genet Metab. 2007 May;91(1):85-97. Epub 2007 Mar 21. [PubMed:17369066 ]
HMDB0000939S-Adenosylhomocysteine979-92-0ThumbC14H20N6O5S384.411
384.12158847		Not Available
HMDB0001185S-Adenosylmethionine485-80-3ThumbC15H23N6O5S399.445
399.145063566		Not Available
HMDB0001248FAD146-14-5ThumbC27H33N9O15P2785.5497
785.157134455		Not Available
HMDB0001520Flavin mononucleotide146-17-8ThumbC17H21N4O9P456.3438
456.104614802		Not Available
HMDB0002308Hydroxocobalamin13422-51-0ThumbC62H89CoN13O15P1346.3551
1345.567070949
  1. Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. [PubMed:17139284 ]
  2. Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. [PubMed:17016423 ]
HMDB0003429Cob(I)alamin18534-66-2ThumbC62H89CoN13O14P1330.378
1329.572151		Not Available
HMDB0006316Cob(II)alamin14463-33-3ThumbC62H89CoN13O14P1330.377
1329.571053		Not Available
Displaying all 11 metabolite protein links