- Metabolite
- HMDB0000211 (myo-Inositol)
- Biospecimen
- Cerebrospinal Fluid (CSF)
- Status
- Detected and Quantified
- Data source
- Referenced
- Concentration
- 158.8 +/- 46.07 uM
- Age
- Adult (>18 years old)
- Sex
- Not Specified
- Condition
- Normal
References
- Huang W, Alexander GE, Daly EM, Shetty HU, Krasuski JS, Rapoport SI, Schapiro MB: High brain myo-inositol levels in the predementia phase of Alzheimer's disease in adults with Down's syndrome: a 1H MRS study. Am J Psychiatry. 1999 Dec;156(12):1879-86. [PubMed:10588400 ]
- De Stefano N, Mortilla M, Federico A: Proton magnetic resonance spectroscopy of the brain in dementia. Ital J Neurol Sci. 1999;20(5 Suppl):S258-64. [PubMed:10662965 ]
- Groenen PM, Peer PG, Wevers RA, Swinkels DW, Franke B, Mariman EC, Steegers-Theunissen RP: Maternal myo-inositol, glucose, and zinc status is associated with the risk of offspring with spina bifida. Am J Obstet Gynecol. 2003 Dec;189(6):1713-9. [PubMed:14710103 ]
- Groenen PM, Klootwijk R, Schijvenaars MM, Straatman H, Mariman EC, Franke B, Steegers-Theunissen RP: Spina bifida and genetic factors related to myo-inositol, glucose, and zinc. Mol Genet Metab. 2004 Jun;82(2):154-61. [PubMed:15172003 ]
- Dunne VG, Bhattachayya S, Besser M, Rae C, Griffin JL: Metabolites from cerebrospinal fluid in aneurysmal subarachnoid haemorrhage correlate with vasospasm and clinical outcome: a pattern-recognition 1H NMR study. NMR Biomed. 2005 Feb;18(1):24-33. [PubMed:15455468 ]
- A J, Trygg J, Gullberg J, Johansson AI, Jonsson P, Antti H, Marklund SL, Moritz T: Extraction and GC/MS analysis of the human blood plasma metabolome. Anal Chem. 2005 Dec 15;77(24):8086-94. [PubMed:16351159 ]
- Shoda J, Tanaka N, Osuga T, Matsuura K, Miyazaki H: Altered bile acid metabolism in liver disease: concurrent occurrence of C-1 and C-6 hydroxylated bile acid metabolites and their preferential excretion into urine. J Lipid Res. 1990 Feb;31(2):249-59. [PubMed:2324645 ]
- Kusmierz J, DeGeorge JJ, Sweeney D, May C, Rapoport SI: Quantitative analysis of polyols in human plasma and cerebrospinal fluid. J Chromatogr. 1989 Dec 29;497:39-48. [PubMed:2625478 ]
- Shoda J, Mahara R, Osuga T, Tohma M, Ohnishi S, Miyazaki H, Tanaka N, Matsuzaki Y: Similarity of unusual bile acids in human umbilical cord blood and amniotic fluid from newborns and in sera and urine from adult patients with cholestatic liver diseases. J Lipid Res. 1988 Jul;29(7):847-58. [PubMed:3411245 ]
- Shetty HU, Schapiro MB, Holloway HW, Rapoport SI: Polyol profiles in Down syndrome. myo-Inositol, specifically, is elevated in the cerebrospinal fluid. J Clin Invest. 1995 Feb;95(2):542-6. [PubMed:7860736 ]
- Shetty HU, Holloway HW, Schapiro MB: Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease. Clin Chem. 1996 Feb;42(2):298-302. [PubMed:8595727 ]
- Acevedo LD, Holloway HW, Rapoport SI, Shetty HU: Application of stable isotope tracer combined with mass spectrometric detection for studying myo-inositol uptake by cultured neurons from fetal mouse: effect of trisomy 16. J Mass Spectrom. 1997 Apr;32(4):395-400. [PubMed:9130398 ]
- Michaelis T, Videen JS, Linsey MS, Ross BD: Dialysis and transplantation affect cerebral abnormalities of end-stage renal disease. J Magn Reson Imaging. 1996 Mar-Apr;6(2):341-7. [PubMed:9132100 ]